Allele Dmel\Lar^unspecified

General Information
Symbol	Dmel\Lar^unspecified	Species	D. melanogaster
Name		FlyBase ID	FBal0118426
Feature type	allele	Associated gene	Dmel\Lar

Allele class
Mutagen
Recent Updates
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Cytology
Phenotypic Data
Phenotypic Class
	female sterile (Astigarraga et al., 2010) neuroanatomy defective (Astigarraga et al., 2010)
Phenotype Manifest In
	medulla (Astigarraga et al., 2010) photoreceptor cell R7 (Astigarraga et al., 2010)
Detailed Description
	Statement Reference The majority of R7 axons terminate prematurely in the same target layer in the medulla, M3, as R8 axons. (Astigarraga et al., 2010)
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
NOT suppressed by
Statement Reference Lar^unspecified has female sterile phenotype, non-suppressible by Liprin-γ^H1/Liprin-γ^S1 (Astigarraga et al., 2010) Lar^unspecified has neuroanatomy defective phenotype, non-suppressible by Liprin-γ^H1/Liprin-γ^S1 (Astigarraga et al., 2010)
Other
Statement Reference Lar^unspecified, Liprin-β^Δ51 has neuroanatomy defective phenotype (Astigarraga et al., 2010) Lar^unspecified, Liprin-β^Δ83 has neuroanatomy defective phenotype (Astigarraga et al., 2010)
Phenotype Manifest In
NOT suppressed by
Statement Reference Lar^unspecified has medulla phenotype, non-suppressible by Liprin-γ^H1/Liprin-γ^S1 (Astigarraga et al., 2010) Lar^unspecified has photoreceptor cell R7 phenotype, non-suppressible by Liprin-γ^H1/Liprin-γ^S1 (Astigarraga et al., 2010)
Other
Statement Reference Lar^unspecified, Liprin-β^Δ51 has medulla phenotype (Astigarraga et al., 2010) Lar^unspecified, Liprin-β^Δ51 has photoreceptor cell R7 phenotype (Astigarraga et al., 2010) Lar^unspecified, Liprin-β^Δ83 has medulla phenotype (Astigarraga et al., 2010) Lar^unspecified, Liprin-β^Δ83 has photoreceptor cell R7 phenotype (Astigarraga et al., 2010)
Additional Comments
Genetic Interactions
Statement Reference In Lar[unspecified], Liprin-β[Δ83] or Lar[unspecified], Liprin-β[Δ51] double mutants, many R7 axons terminate prematurely in the M3 layer of the medulla. However, a few R7 axons extend far beyond the boundary of the medulla. (Astigarraga et al., 2010)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Fails to complement	Lar²¹²⁷ (Maurel-Zaffran et al., 2001) Lar^C12 (Maurel-Zaffran et al., 2001) Lar^C105 (Maurel-Zaffran et al., 2001) Lar^C219 (Maurel-Zaffran et al., 2001) Lar^G50 (Maurel-Zaffran et al., 2001) Lar^K470 (Maurel-Zaffran et al., 2001)
Rescued by	Lar^unspecified is rescued by Scer\GAL4^elav-C155/Lar^Scer\UAS.cKa (Krueger et al., 1996)
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	Lar (Astigarraga et al., 2010) Lar^unspecified
Name Synonym
Secondary FlyBase IDs

References ( 3 )
Research paper	Astigarraga et al., 2010, J. Neurosci. 30(46): 15358--15368 Three Drosophila liprins interact to control synapse formation. [FBrf0212351] Maurel-Zaffran et al., 2001, Neuron 32(2): 225--235 Cell-autonomous and -nonautonomous functions of LAR in R7 photoreceptor axon targeting. [FBrf0139775] Krueger et al., 1996, Cell 84(4): 611--622 The transmembrane tyrosine phosphatase DLAR controls motor axon guidance in Drosophila. [FBrf0086508]

Allele Dmel\Larunspecified

Allele Dmel\Lar^unspecified