The P{EP} insertion is 257bp upstream of the putative ATG start codon in the same orientation to the transcription unit.
Expression of Nup44AEP2417 under the control of Scer\GAL4Cha.7.4 results in a rough eye phenotype.
Expression of Nup44AEP2417 under the control of Scer\GAL4GMR.PF does not result in a rough eye phenotype.
Nup44AEP2417, Scer\GAL4GMR.PF is a non-enhancer of visible phenotype of Hsap\MAPTV337M.UAS, Scer\GAL4GMR.PF
Nup44AEP2417, Scer\GAL4GMR.PF is a non-suppressor of visible phenotype of Hsap\MAPTV337M.UAS, Scer\GAL4GMR.PF
Nup44AEP2417, Scer\GAL4GMR.PF is a non-enhancer of eye phenotype of Hsap\MAPTV337M.UAS, Scer\GAL4GMR.PF
Nup44A[+]/Nup44AEP2417 is a suppressor | partially of egg chamber phenotype of mio2/mio1
Nup44AEP2417, Scer\GAL4GMR.PU is a suppressor of retina phenotype of Hsap\ATXN182Q.UAS, Scer\GAL4GMR.PU
Nup44AEP2417, Scer\GAL4GMR.PF is a suppressor of eye phenotype of Hsap\ATXN182Q.UAS, Scer\GAL4GMR.PF
Nup44AEP2417, Scer\GAL4GMR.PF is a suppressor of retina phenotype of Hsap\ATXN182Q.UAS, Scer\GAL4GMR.PF
Nup44AEP2417, Scer\GAL4GMR.PU is a non-suppressor of retina phenotype of Hsap\HTT128Q.1-336.UAS, Scer\GAL4GMR.PU
Nup44AEP2417, Scer\GAL4GMR.PF is a non-suppressor of eye phenotype of Hsap\MAPTV337M.UAS, Scer\GAL4GMR.PF
Nup44AEP2417/+ partially suppresses the mio1/mio2 oogenesis phenotype. In contrast to mio1/mio2 single mutants, egg chambers from Nup44AEP2417/+, mio1/mio2 females frequently progress through vitellogenesis to produce mature eggs. Moreover, a small percentage of the eggs laid by Nup44AEP2417/+, mio1/mio2 females hatch and develop into viable adults.
Expression of Nup44AEP2417 does not suppress the retinal phenotype seen when Hsap\HTT128Q.1-336.Scer\UAS is expressed under the control of Scer\GAL4GMR.PU.
Expression of Nup44AEP2417 suppresses the retinal phenotype seen when Hsap\ATXN182Q.Scer\UAS is expressed under the control of Scer\GAL4GMR.PU.
The rough eye phenotype caused by expression of Hsap\MAPTV337M.Scer\UAS under the control of Scer\GAL4GMR.PF is not modified if the flies are also carrying Nup44AEP2417.