FB2025_01 , released February 20, 2025
Allele: Dmel\inscEP2010
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General Information
Symbol
Dmel\inscEP2010
Species
D. melanogaster
Name
FlyBase ID
FBal0119238
Feature type
allele
Associated gene
Dmel\insc
Associated Insertion(s)
P{EP}inscEP2010
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Pena-Rangel et al., 2002, Gene Disruption Project members, 2001-, Abdelilah-Seyfried et al., 2000)
Progenitor genotype
Associated Insertion(s)
P{EP}inscEP2010
Cytology
Description

P{EP} insertion at -184bp relative to the start of the transcription unit.

(Abdelilah-Seyfried et al., 2000)
Allele components
Component
Use(s)
Inserted element
P{EP}
Regulatory region(s)
UAS
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of inscEP2010 under the control of Scer\GAL4sca-537.4 results in loss of several scutellar macrochaetae. Sensory organs with no socket and one shaft, one socket and two shafts and no socket, no shaft and one sheath cell are seen.

      (Abdelilah-Seyfried et al., 2000)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      Scer\GAL4sca-537.4/inscEP2010 is an enhancer of phenotype of N55e11

      (Abdelilah-Seyfried et al., 2000)

      Scer\GAL4sca-537.4/inscEP2010 is an enhancer of phenotype of HE21

      (Abdelilah-Seyfried et al., 2000)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      It is not clear whether the phenotype caused by overexpression from the P{EP}inscEP2010 insertion is entirely due to altered expression of insc; sktl is present in the first intron of insc and it is not clear whether misexpression of insc, sktl or both is driven by the P{EP}inscEP2010 insertion.

      (Abdelilah-Seyfried et al., 2000)

      Selected as: a P{EP} insertion line that modifies the pnrMD237/+ phenotype when expressed using Scer\GAL4pnr-MD237.

      (Pena-Rangel et al., 2002)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      EP(2)2010
      (Abdelilah-Seyfried et al., 2000)
      inscEP2010
      Name Synonyms
      Secondary FlyBase IDs
        References (3)