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General Information
Symbol
Dmel\Cdk2UAS.Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0119310
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-Cdk2-myc, UAS-Cdk2
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt sequences drive expression of Cdk2 tagged with six epitope copies of the Tag:MYC tag at the C terminus.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

When driven by Scer\GAL4hs.2sev, Scer\GAL4GMR.PF or Scer\GAL4ey.PH, no eye phenotype is seen.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
NOT Suppressor of
Phenotype Manifest In
NOT Suppressor of
Statement
Reference
Other
Statement
Reference

CycEUAS.cLa, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF, Cdk2UAS.Tag:MYC has eye disc & photoreceptor cell phenotype

Additional Comments
Genetic Interactions
Statement
Reference

Co-expression of Cdk2Scer\UAS.T:Hsap\MYC with CycEScer\UAS.cLa driven by Scer\GAL4GMR.PF blocks some photoreceptor differentiation in the third instar eye disc. The phenotype of these discs is largely unaffected by upd1Scer\UAS.cCa.

When a combination of CycDScer\UAS.cDa and cdc2cScer\UAS.T:Hsap\MYC are driven by either, Scer\GAL4hs.2sev, Scer\GAL4GMR.PF or Scer\GAL4ey.PH no eye phenotype is seen.

Xenogenetic Interactions
Statement
Reference

Expression of cdc2cScer\UAS.T:Hsap\MYC does not suppress the eye phenotypes seen when Mmus\Shisa5Scer\UAS.cGa is expressed under the control of Scer\GAL4ey.PH.

Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
Cdk2Scer\UAS.T:Hsap\MYC
Cdk2UAS.Tag:MYC
cdc2cScer\UAS.T:Hsap\MYC
Name Synonyms
Secondary FlyBase IDs
    References (10)