P{EP} insertion at +222bp of the transcription unit (the CDS starts at +189bp).
Approximately 50% of homozygous stage 13-14 embryos have abnormally shaped and less elongated lateral epidermal cells than normal. 35% of homozygous embryos show intermittent loss of PTyr-enriched actin-nucleating centers that form between neighbouring dorsal-most epidermal cells. Some of the mutant embryos show widening of some of the dorsal-most epidermal cells and disruptions in the leading edge. The embryos show partial to near complete disruptions of the cell boundaries of the amnioserosa. Rab11EP3017/Df(3R)e-R1 embryos show similar defects in the dorsal-most epidermal cells, amnioserosa and the lateral epidermis, at a comparable penetrance.
Testes from Rab1193Bi/Rab11EP3017 larvae have spermatids composed of an abnormally large Nebenkern associated with multiple nuclei.
Homozygous clones in the eye lack all photoreceptor cells and lack interommatidial bristles.
Adult Rab11mo/Rab11EP3017 escapers have eye defects including fused ommatidia and missing bristles.
Few mutant photoreceptors are seen in mosaic eyes, probably reflecting a cell-essential role for Rab11. These mutant photoreceptors are reduced in size and a profusion of vesicles fills the photoreceptor cytoplasm. The normal multivesicular bodies (MVBs) are missing in these mutant cells, but infrequently, irregular vesicular organelles resembling defective MVBs are seen. The ER and Golgi have a normal appearance in these cells.
Egg chambers older than stage 4 are never detected in females containing homozygous germ-line clones.
Expression of Rab11EP3017 under the control of Scer\GAL4sca-537.4 results in the loss of scutellar and dorsocentral macrochaetae. Sensory organs with no socket, one shaft and one sheath cell are seen.
Rab11EP3017, Scer\GAL4sca-537.4 has visible phenotype, non-enhanceable by N[+]/N55e11
Rab11EP3017, Scer\GAL4sca-537.4 has visible phenotype, non-suppressible by N[+]/N55e11
Rab11EP3017/Scer\GAL4sca-537.4 is a non-enhancer of phenotype of N55e11
Order of alleles (based on transheterozygous sterile phenotype): Rab1193Bi < Rab11j2D1 < Rab11EP3017 = Rab11ETo11 = Rab11ETo3 < Df(3R)e-N19.