FB2025_02 , released April 17, 2025
Allele: Dmel\MESR3EP2221
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General Information
Symbol
Dmel\MESR3EP2221
Species
D. melanogaster
Name
FlyBase ID
FBal0119463
Feature type
allele
Associated gene
Dmel\MESR3
Associated Insertion(s)
P{EP}MESR3EP2221
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Gene Disruption Project members, 2001-, Huang and Rubin, 2000)
Progenitor genotype
Associated Insertion(s)
P{EP}MESR3EP2221
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{EP}
Regulatory region(s)
UAS
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
AF195497
AAG28469
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      MESR3EP2221/Scer\GAL4hs.2sev is an enhancer of visible phenotype of ksr::torΔNksr.hs.sev

      (Huang and Rubin, 2000)
      Suppressor of
      Statement
      Reference

      MESR3EP2221/Scer\GAL4hs.2sev is a suppressor of visible phenotype of Ras85DV12.sev

      (Huang and Rubin, 2000)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      MESR3EP2221/Scer\GAL4hs.2sev is an enhancer of eye phenotype of ksr::torΔNksr.hs.sev

      (Huang and Rubin, 2000)
      Suppressor of
      Statement
      Reference

      MESR3EP2221/Scer\GAL4hs.2sev is a suppressor of eye phenotype of Ras85DV12.sev

      (Huang and Rubin, 2000)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Moderate enhancer of ksr::torΔNksr.hs.sev and very strong suppressor of Ras85DV12.sev, when expression is driven by Scer\GAL4hs.2sev.

      (Huang and Rubin, 2000)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 2 )
      Crossreferences
      GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
      GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      MESR32221
      MESR3EP2221
      Name Synonyms
      Secondary FlyBase IDs
        References (2)