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General Information
Symbol
Dmel\wdbEP3559
Species
D. melanogaster
Name
FlyBase ID
FBal0119629
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

The orientation of the P{EP} element is the same as the direction of wdb transcription.

The P{EP} element is inserted within the 5' UTR.

Insertion components
P{EP}EP3559
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of wdbEP3559 in the eye under the control of Scer\GAL4GMR.PF results in very mild defects in ommatidial organisation.

Expression of wdbEP3559 under the control of Scer\GAL4GMR.PF results in a big eye phenotype.

Expression of wdbEP3559 under the control of Scer\GAL4tim.PE lengthens the period of locomotor activity rhythms; the period is about 0.7 hours longer than that of controls. The lengthening of the period is dose-dependent; the period is increased by 1.5-2 hours if the temperature is increased to 29oC or two copies of wdbEP3559 are present. 5% of the flies are arrhythmic after about 4 days in constant darkness conditions.

Expression of wdbEP3559 under the control of Scer\GAL4GMR.PF results in a very mild rough eye phenotype.

Expression of wdbEP3559 under the control of Scer\GAL4ap-md544 results in many cells forming multiple wing hairs; an average of 49+/-20 cells in the fifth wing cell have a multiple wing hair phenotype.

Mutant larvae expressing wdbEP3559 under the control of Scer\GAL4elav-C155 have reduced or abnormal synapses. Mutant larvae expressing wdbEP3559 under the control of Scer\GAL4elav-C155 have ISN neuron pathfinding defects.

Expression of wdbEP3559 under the control of Scer\GAL4sca-537.4 results in sensory organs with two sockets and two shafts, two sockets and one shaft, one socket and two shafts and dot-like socket morphology.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
NOT Enhanced by
Statement
Reference
NOT suppressed by
Statement
Reference

Scer\GAL4sca-537.4, wdbEP3559 has visible phenotype, non-suppressible by H[+]/HE21

Enhancer of
NOT Enhancer of
Suppressor of
NOT Suppressor of
Phenotype Manifest In
Suppressed by
Enhancer of
NOT Enhancer of
Suppressor of
NOT Suppressor of
Additional Comments
Genetic Interactions
Statement
Reference

Expression of wdbEP3559 in animals expressing foxoGS9928 under the control of Scer\GAL4GMR.PF enhances the eye phenotype.

Expression of one copy of wdbEP3559 under the control of Scer\GAL4tim.PE in a dcoL background lengthens the period of locomotor activity rhythms from 24.7 to 26 hours. Expression of one copy of wdbEP3559 under the control of Scer\GAL4tim.PE in a dcog background lengthens the period of locomotor activity rhythms from 27.6 to 30.3 hours.

Xenogenetic Interactions
Statement
Reference

The rough eye phenotype caused by expression of Hsap\MAPTV337M.Scer\UAS under the control of Scer\GAL4GMR.PF is enhanced by wdbEP3559.

Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer
Comments
Comments

Precise excision of the P{EP} element reverts the modifying effect of wdbEP3559 on the rough eye phenotype caused by expression of Hsap\MAPTV337M.Scer\UAS under the control of Scer\GAL4GMR.PF.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (10)