FlyBase Allele Report: Dmel\SNF4Aγ[EP3015b]

General Information

Symbol

Dmel\SNF4Aγ^EP3015b

Species

D. melanogaster

Name

FlyBase ID

FBal0119634

Feature type

allele

Associated gene

Dmel\SNF4Aγ

Associated Insertion(s)

P{EP}SNF4Aγ^EP3015b

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Gene Disruption Project members, 2001-, Abdelilah-Seyfried et al., 2000)

Progenitor genotype

Associated Insertion(s)

P{EP}SNF4Aγ^EP3015b

Cytology

Description

P{EP} insertion.

(Abdelilah-Seyfried et al., 2000)

Allele components

Component

Use(s)

Inserted element

P{EP}

misexpression element

Regulatory region(s)

UAS

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3R:21,204,759..21,204,759 [+]

(Di Cara et al., 2013, Cao et al., 2008, Lippai et al., 2008, Schulz et al., 2004, Gene Disruption Project members, 2001-, Abdelilah-Seyfried et al., 2000)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

exacerbates Alzheimer's disease

modeled by Hsap\APP^{Aβ42.GMR.Tag:SS(rPENK)}

(Cao et al., 2008)

exacerbates Huntington's disease

modeled by Hsap\HTT^Q93.ex1.UAS

(Cao et al., 2008)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal

(Lippai et al., 2008)

visible, with Scer\GAL4^sca-537.4

(Abdelilah-Seyfried et al., 2000)

Phenotype Manifest In

scutellar bristle | ectopic, with Scer\GAL4^sca-537.4

(Abdelilah-Seyfried et al., 2000)

tormogen cell, with Scer\GAL4^sca-537.4

(Abdelilah-Seyfried et al., 2000)

trichogen cell, with Scer\GAL4^sca-537.4

(Abdelilah-Seyfried et al., 2000)

Detailed Description

Statement

Reference

Expression using Scer\GAL4^ey.PU does not induce a rough eye phenotype.

(Cao et al., 2008)

Homozygotes die before the third larval instar stage.

(Lippai et al., 2008)

Expression of SNF4Aγ^EP3015b under the control of Scer\GAL4^sca-537.4 results in additional scutellar macrochaetae. Sensory organs with no socket, one shaft and one sheath cell, no socket, no shaft and one sheath cell and one socket and no shaft are seen. Short and thickened shaft morphology is seen.

(Abdelilah-Seyfried et al., 2000)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

Hsap\MAPT^UAS.cWa, SNF4Aγ^EP3015b, Scer\GAL4^ey.PU has lethal phenotype

(Cao et al., 2008)

Phenotype Manifest In

Enhancer of

Statement

Reference

SNF4Aγ^EP3015b is an enhancer of eye | temperature conditional phenotype of Invadolysin^UAS.N.Tag:HA, Scer\GAL4^GMR.PF

(Di Cara et al., 2013)

SNF4Aγ^EP3015b is an enhancer of ommatidium | temperature conditional phenotype of Invadolysin^UAS.N.Tag:HA, Scer\GAL4^GMR.PF

(Di Cara et al., 2013)

SNF4Aγ^EP3015b is an enhancer of interommatidial bristle | temperature conditional phenotype of Invadolysin^UAS.N.Tag:HA, Scer\GAL4^GMR.PF

(Di Cara et al., 2013)

SNF4Aγ^EP3015b, Scer\GAL4^GMR.PU is an enhancer of eye phenotype of Hsap\HTT^Q93.ex1.UAS, Scer\GAL4^GMR.PU

(Cao et al., 2008)

SNF4Aγ^EP3015b/Scer\GAL4^ey.PU is an enhancer of eye phenotype of Hsap\APP^{Aβ42.GMR.Tag:SS(rPENK)}

(Cao et al., 2008)

Additional Comments

Genetic Interactions

Statement

Reference

The rough eye phenotype seen upon expression of Invadolysin^{Scer\UAS.N.T:Ivir\HA1} at 29[o]C under the control of Scer\GAL4^GMR.PF, is enhanced by a heterozygous SNF4Aγ^EP3015b background.

(Di Cara et al., 2013)

Expression from the P{EP} elements in the "EP(3)3015" line (which contains P{EP}EP3015a^EP3015a and P{EP}SNF4Aγ^EP3015b) under the control of Scer\GAL4^ptc-559.1 (the animals are initially raised at 18^oC and then shifted to 29^oC after 10 days) results in a reduced number of early germ cells (stem cells, gonialblasts and spermatogonia) in the testis.

(Schulz et al., 2004)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Separable from: P{EP}EP3015a^EP3015a.

(Abdelilah-Seyfried et al., 2000)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

EP(3)3015b

(Abdelilah-Seyfried et al., 2001, Abdelilah-Seyfried et al., 2000)

EP3015b^EP3015b

SNF4Aγ^EP3015b

(Di Cara et al., 2013)

Name Synonyms

Secondary FlyBase IDs

References (7)

Report Sections

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