FlyBase Allele Report: Dmel\Hr4[EP1232]

General Information

Symbol

Dmel\Hr4^EP1232

Species

D. melanogaster

Name

FlyBase ID

FBal0119652

Feature type

allele

Associated gene

Dmel\Hr4

Associated Insertion(s)

P{EP}Hr4^EP1232

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Pena-Rangel et al., 2002, Tseng and Hariharan, 2002, Gene Disruption Project members, 2001-, Abdelilah-Seyfried et al., 2000)

Progenitor genotype

Associated Insertion(s)

P{EP}Hr4^EP1232

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{EP}

misexpression element

Regulatory region(s)

UAS

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

X:1,951,679..1,951,679 [+]

(Müller et al., 2005, Pena-Rangel et al., 2002, Tseng and Hariharan, 2002, Gene Disruption Project members, 2001-, Abdelilah-Seyfried et al., 2000)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

partially lethal - majority die, with Scer\GAL4^en-e16E

(Tseng and Hariharan, 2002)

visible, with Scer\GAL4^en-e16E

(Tseng and Hariharan, 2002)

visible, with Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

visible, with Scer\GAL4^GMR.PF

(Müller et al., 2005)

visible, with Scer\GAL4^hs.2sev

(Tseng and Hariharan, 2002)

visible, with Scer\GAL4^sca-537.4

(Abdelilah-Seyfried et al., 2000)

wild-type, with Scer\GAL4^ap-md544

(Pena-Rangel et al., 2002)

Phenotype Manifest In

dorsocentral bristle, with Scer\GAL4^sca-537.4

(Abdelilah-Seyfried et al., 2000)

eye, with Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

eye, with Scer\GAL4^GMR.PF

(Müller et al., 2005)

eye, with Scer\GAL4^hs.2sev

(Tseng and Hariharan, 2002)

ommatidium, with Scer\GAL4^hs.2sev

(Tseng and Hariharan, 2002)

scutellar bristle, with Scer\GAL4^sca-537.4

(Abdelilah-Seyfried et al., 2000)

tormogen cell, with Scer\GAL4^sca-537.4

(Abdelilah-Seyfried et al., 2000)

wing, with Scer\GAL4^en-e16E

(Tseng and Hariharan, 2002)

Detailed Description

Statement

Reference

Expression of CG3600^EP1232 under the control of Scer\GAL4^GMR.PF results in large, rough eyes.

(Müller et al., 2005)

Expression of CG3600^EP1232 under the control of Scer\GAL4^ey.PH results in eyes that are somewhat reduced in size. Flies expressing CG3600^EP1232 under the control of Scer\GAL4^hs.2sev have rough, slightly glassy eyes. Flies expressing CG3600^EP1232 under the control of Scer\GAL4^en-e16E have folds in the wing.

(Tseng and Hariharan, 2002)

Expression of CG3600^EP1232 under the control of Scer\GAL4^sca-537.4 results in the loss of external support cells of a few scutellar and dorsocentral macrochaetae without loss of the sheath cell. Sensory organs with no socket and one shaft are seen.

(Abdelilah-Seyfried et al., 2000)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

Hr4^EP1232, Scer\GAL4^sca-537.4 has visible phenotype, non-enhanceable by N[+]/N^55e11

(Abdelilah-Seyfried et al., 2000)

NOT suppressed by

Statement

Reference

Hr4^EP1232, Scer\GAL4^ey.PH has visible phenotype, non-suppressible by CycE^UAS.cLa, Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

Hr4^EP1232, Scer\GAL4^sca-537.4 has visible phenotype, non-suppressible by N[+]/N^55e11

(Abdelilah-Seyfried et al., 2000)

Enhancer of

Statement

Reference

Hr4^EP1232/Scer\GAL4^pnr-MD237 is an enhancer of visible phenotype of pnr^MD237

(Pena-Rangel et al., 2002)

Suppressor of

Statement

Reference

Hr4^EP1232, Scer\GAL4^GMR.PF is a suppressor of visible phenotype of H^UAS.cMa, Scer\GAL4^GMR.PF

(Müller et al., 2005)

Hr4^EP1232/Scer\GAL4^GMR.PF is a suppressor | partially of visible phenotype of p53^GMR.Ex

(Müller et al., 2005)

Hr4^EP1232/Scer\GAL4^GMR.PF is a suppressor of visible phenotype of hid^GMR.PG

(Müller et al., 2005)

Hr4^EP1232/Scer\GAL4^GMR.PF is a suppressor of visible phenotype of grim^GMR.PC

(Müller et al., 2005)

Hr4^EP1232/Scer\GAL4^GMR.PF is a suppressor of visible phenotype of rpr^GMR.PW

(Müller et al., 2005)

Phenotype Manifest In

NOT suppressed by

Statement

Reference

Hr4^EP1232, Scer\GAL4^ey.PH has eye phenotype, non-suppressible by CycE^UAS.cLa, Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

Enhancer of

Statement

Reference

Hr4^EP1232/Scer\GAL4^pnr-MD237 is an enhancer of chaeta phenotype of pnr^MD237

(Pena-Rangel et al., 2002)

NOT Enhancer of

Statement

Reference

Hr4^EP1232/Scer\GAL4^sca-537.4 is a non-enhancer of phenotype of N^55e11

(Abdelilah-Seyfried et al., 2000)

Suppressor of

Statement

Reference

Hr4^EP1232/Scer\GAL4^GMR.PF is a suppressor of eye phenotype of rpr^GMR.PW

(Müller et al., 2005)

Hr4^EP1232, Scer\GAL4^GMR.PF is a suppressor of eye phenotype of H^UAS.cMa, Scer\GAL4^GMR.PF

(Müller et al., 2005)

Hr4^EP1232/Scer\GAL4^GMR.PF is a suppressor | partially of eye phenotype of p53^GMR.Ex

(Müller et al., 2005)

Hr4^EP1232/Scer\GAL4^GMR.PF is a suppressor of eye phenotype of hid^GMR.PG

(Müller et al., 2005)

Hr4^EP1232/Scer\GAL4^GMR.PF is a suppressor of eye phenotype of grim^GMR.PC

(Müller et al., 2005)

Other

Statement

Reference

Hr4^EP1232, Scer\GAL4^pnr-MD237, pnr^MD237/pnr[+] has macrochaeta phenotype

(Pena-Rangel et al., 2002)

Hr4^EP1232, Scer\GAL4^pnr-MD237, pnr^MD237/pnr[+] has microchaeta phenotype

(Pena-Rangel et al., 2002)

Hr4^EP1232, Scer\GAL4^pnr-MD237, pnr^MD237 has macrochaeta phenotype

(Pena-Rangel et al., 2002)

Hr4^EP1232, Scer\GAL4^pnr-MD237, pnr^MD237 has microchaeta phenotype

(Pena-Rangel et al., 2002)

Additional Comments

Genetic Interactions

Statement

Reference

pnr^MD237/+ adults expressing CG3600^EP1232 under the control of Scer\GAL4^pnr-MD237 show loss of some macrochaetae and microchaetae.

(Pena-Rangel et al., 2002)

Co-expression of CycE^Scer\UAS.cLa does not suppress the small eye phenotype caused by expression of CG3600^EP1232 under the control of Scer\GAL4^ey.PH.

(Tseng and Hariharan, 2002)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Kyoto

122041

w¹¹¹⁸ P{EP}Hr4^EP1232

Notes on Origin

Discoverer

Selected as: a P{EP} insertion line that modifies the pnr^MD237/+ phenotype when expressed using Scer\GAL4^pnr-MD237.

(Pena-Rangel et al., 2002)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

CG3600^EP1232

EP1232^EP1232

(Abdelilah-Seyfried et al., 2000)

Hr4^EP1232

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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