FlyBase Allele Report: Dmel\Adf1[EP815]

General Information

Symbol

Dmel\Adf1^EP815

Species

D. melanogaster

Name

FlyBase ID

FBal0119718

Feature type

allele

Associated gene

Dmel\Adf1

Associated Insertion(s)

P{EP}Adf1^EP815

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Gene Disruption Project members, 2001-, Kraut et al., 2001, Kraut et al., 2001, Abdelilah-Seyfried et al., 2000)

Progenitor genotype

Associated Insertion(s)

P{EP}Adf1^EP815

Cytology

Description

The P{EP} element is inserted within the 5' UTR.

(Kraut et al., 2001)

P{EP} insertion at +8bp of the transcription unit.

(Abdelilah-Seyfried et al., 2000)

Allele components

Component

Use(s)

Inserted element

P{EP}

misexpression element

Regulatory region(s)

UAS

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2R:6,662,289..6,662,289 [+]

(Levine et al., 2007, Gene Disruption Project members, 2001-, Kraut et al., 2001, Kraut et al., 2001, Abdelilah-Seyfried et al., 2000)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy | larval stage, with Scer\GAL4^elav-C155

(Kraut et al., 2001)

visible, with Scer\GAL4^ptc-559.1

(Abdelilah-Seyfried et al., 2000)

Phenotype Manifest In

anterior fascicle & synapse, with Scer\GAL4^elav-C155

(Kraut et al., 2001)

dorsocentral bristle | ectopic, with Scer\GAL4^ptc-559.1

(Abdelilah-Seyfried et al., 2000)

larval intersegmental nerve, with Scer\GAL4^elav-C155

(Kraut et al., 2001)

scutellar bristle | ectopic, with Scer\GAL4^ptc-559.1

(Abdelilah-Seyfried et al., 2000)

Detailed Description

Statement

Reference

Mutant larvae expressing Adf1^EP815 under the control of Scer\GAL4^elav-C155 have ISN neuron pathfinding defects. Mutant larvae expressing Adf1^EP815 under the control of Scer\GAL4^elav-C155 have reduced or abnormal synapses.

(Kraut et al., 2001)

Expression of Adf1^EP815 under the control of Scer\GAL4^ptc-559.1 results in additional scutellar and dorsocentral macrochaetae.

(Abdelilah-Seyfried et al., 2000)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

Adf1^EP815, Scer\GAL4^sca-537.4 has visible phenotype, non-enhanceable by N[+]/N^55e11

(Abdelilah-Seyfried et al., 2000)

NOT suppressed by

Statement

Reference

Adf1^EP815, Scer\GAL4^sca-537.4 has visible phenotype, non-suppressible by N[+]/N^55e11

(Abdelilah-Seyfried et al., 2000)

Phenotype Manifest In

NOT Enhancer of

Statement

Reference

Scer\GAL4^sca-537.4/Adf1^EP815 is a non-enhancer of phenotype of N^55e11

(Abdelilah-Seyfried et al., 2000)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Adf1^EP0815

Adf1^EP815

EP(2)0815

(Abdelilah-Seyfried et al., 2000)

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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