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General Information
Symbol
Dmel\dppUAS.E.EGFP
Species
D. melanogaster
Name
FlyBase ID
FBal0120516
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-GFP-Dpp, UAS-Dpp-GFP, GFP-dpp
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of a dpp cDNA which is tagged at codon 465 with EGFP.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of dppUAS.E.EGFP under the control of Scer\GAL4Mhc.PW leads to a decrease in the spontaneous locomotion and in the probability of proboscis extension reflex (PER) when compared to control adults. Its expression under the control of Scer\GAL4GS.Act88F in RU486 fed animals leads to a decrease in the spontaneous locomotion particularly in proximity to the food and an increase in the probability of PER when compared to control adults.

Overexpression of dppScer\UAS.E.T:Avic\GFP-EGFP in the wing disc, under the control of Scer\GAL4dpp.blk1 results in pupal lethality.

Eggshells generated from mothers that overexpress dppScer\UAS.E.T:Avic\GFP-EGFP under the control of Scer\GAL455B at 290C in anterior follicle cells show an expanded operculum.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

A Sec152 heterozygous background partially suppresses the pupal lethality caused by Scer\GAL4dpp.blk1-mediated overexpression of dppScer\UAS.E.T:Avic\GFP-EGFP.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

dppScer\UAS.E.T:Avic\GFP-EGFP expressed under the control of Scer\GAL4dpp.blk1 restores normal epidermal structures in dppd12/dppd14 flies. These flies fail to hatch from the pupal case.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
dppScer\UAS.E.T:Avic\GFP-EGFP
dppScer\UAS.E.T:Avic\GFP-F64L.S65T
dppUAS.E.EGFP
Name Synonyms
Secondary FlyBase IDs
    References (19)