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General Information
Symbol
Dmel\bab1Ar07
Species
D. melanogaster
Name
FlyBase ID
FBal0120548
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
babAR07
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Cytology
Nature of the lesion
Statement
Reference
Caused by aberration
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Other
Statement
Reference

bab1Ar07, bab2Ar07 has tarsal segment & joint phenotype

bab1Ar07, bab2Ar07 has antennal segment & joint phenotype

bab1Ar07, bab2Ar07 has adult cuticle & abdominal segment 7 phenotype

bab1Ar07, bab2Ar07 has abdominal tergite 7 & trichome | female phenotype

bab1Ar07, bab2Ar07 has abdominal sternite 7 & trichome | female phenotype

bab1Ar07, bab2Ar07 has abdominal sternite 6 & macrochaeta | female phenotype

bab1Ar07, bab2Ar07 has abdominal sternite 7 & macrochaeta | female phenotype

bab1Ar07, bab2Ar07/bab2[+] has adult cuticle & abdominal segment 5 | female phenotype

bab1Ar07, bab2Ar07 has adult cuticle & abdominal segment 6 | female phenotype

bab1Ar07/bab1[+], bab2Ar07 has adult cuticle & abdominal segment 5 | female phenotype

bab1Ar07, bab2Ar07 has adult cuticle & abdominal segment 2 phenotype

bab1Ar07, bab2Ar07 has adult cuticle & abdominal segment 3 phenotype

bab1Ar07, bab2Ar07 has adult cuticle & abdominal segment 4 phenotype

bab1Ar07, bab2Ar07 has adult cuticle & abdominal segment 5 phenotype

bab1Ar07, bab2Ar07 has adult cuticle & abdominal segment 6 phenotype

Additional Comments
Genetic Interactions
Statement
Reference

bab2E4/Df(3L)babAr07 flies have ectopic sex combs on tarsal segment 2 (7-8 bristles) and tarsal segment 3 (3-4 bristles) and show fusion of tarsal segments 4 and 5. Expression of bab1Scer\UAS.cGa under the control of Scer\GAL4bab1-Pgal4-2 partially rescues the mutant leg phenotypes of bab2E4/Df(3L)babAr07 flies; there is no sex comb on tarsal segment 3, tarsal segments 4 and 5 are separated by a well-defined joint but there is a small sex comb on tarsal segment 2 (1-2 bristles). Expression of bab24.Scer\UAS under the control of Scer\GAL4bab1-Pgal4-2 fully rescues the mutant leg phenotypes of bab2E4/Df(3L)babAr07 flies; tarsal segments 2 and 3 do not have any sex combs and tarsal segments 4 and 5 are always properly separated. bab2E4/Df(3L)babAr07 females have ovaries of reduced size which contain only a few follicles with abnormal orientation. They are subfertile and lay very few eggs. These defects are partially rescued by bab1Scer\UAS.cGa expressed under the control of Scer\GAL4bab1-Pgal4-2 and are fully rescued by bab24.Scer\UAS expressed under the control of Scer\GAL4bab1-Pgal4-2. bab2E4/Df(3L)babAr07 females show increased abdominal pigmentation; segments A5 and A6 are fully pigmented. This defect is not rescued by bab24.Scer\UAS expressed under the control of Scer\GAL4bab1-Pgal4-2.

Tarsal joints are fused or absent in Df(3L)babAr07/Df(3L)babAr07 animals and the a4/a5 and a5/arista joints are missing.

Homozygous Df(3L)babAr07 females have a very strong mutant ovary phenotype; the ovaries are very small and no developing follicles are seen. Df(3L)babAr07 homozygotes have a very strong mutant leg phenotype.

Df(3L)babAr07/+ females shows male-specific pigmentation of A5 and A6. Df(3L)babAr07/Df(3L)babAr07 males and females show ectopic pigmentation in A2-A7 tergites, A4-A7 sternites and occasionally in the A1 tergite. Df(3L)babAr07/Df(3L)babAr07 females expression of posterior morphological characters is increased: trichomes are absent from A7 tergite and sternite and the number of bristles on A6 and A7 sternites is reduced. A6 sternite bears some resemblance to the A6 sternite of males or the A7 sternite of females. The thorn bristles normally present in A8 are replaced by wavy bristles typical of the male A9 genital arch. The ectopic male pigmentation seen in Df(3L)babAr07/+ females is suppressed by Df(3R)Ubx-RS4-8/+.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (7)