FB2025_01 , released February 20, 2025
Allele: Dmel\mTorunspecified
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General Information
Symbol
Dmel\mTorunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0120579
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    Heterozygosity for Tor sensitises larvae to rapamycin. Addition of 1μM rapamycin delays development by about 3 days in wild-type larvae and about 6 days in Tor heterozygotes.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Phenotype Manifest In
    Additional Comments
    Genetic Interactions
    Statement
    Reference

    One copy of Torunspecified suppresses the rescuing effect of AD57 on the lethality of flies expressing RetMEN2B.Scer\UAS under the control of Scer\GAL4ptc-559.1, resulting in an increased frequency of lethality than in the absence of the drug.

    One copy of Torunspecified further enhances the increased lethality seen when flies expressing RetMEN2B.Scer\UAS under the control of Scer\GAL4ptc-559.1 are fed AD58.

    AD58 enhances the wing phenotypes seen in flies expressing RetMEN2B.Scer\UAS under the control of Scer\GAL4C-765 in a Torunspecified/+ background.

    One copy of Torunspecified increases proliferation in the larval wing discs of flies expressing RetMEN2B.Scer\UAS under the control of Scer\GAL4ptc-559.1 that have been fed AD58.

    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (3)
    Reported As
    Symbol Synonym
    Torunspecified
    mTorunspecified
    Name Synonyms
    Secondary FlyBase IDs
      References (3)