FB2025_02 , released April 17, 2025
Allele: Dmel\Su(H)ΔH.UAS
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General Information
Symbol
Dmel\Su(H)ΔH.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0120612
Feature type
allele
Associated gene
Dmel\Su(H)
Associated Insertion(s)
Carried in Construct
P{UAS-Su(H).ΔH}
Key Links
Transgenic product class
inframe_deletion
(Furriols and Bray, 2000)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Furriols and Bray, 2000)
Mutagen
in vitro construct
(Furriols and Bray, 2000)
Progenitor genotype
Carried in construct
P{UAS-Su(H).ΔH}
Cytology
Description

Amino acids 18 to 457 of Su(H) is expressed under the control of UASt sequences (the deletion removes the carboxy-terminal 137 amino acids which encompass the H-binding domain.

(Furriols and Bray, 2000)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Su(H)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      When Su(H)ΔH.Scer\UAS is driven by Scer\GAL4ptc-559.1, the loss of the anterior cross vein and nicks of the distal wing margin are occasionally seen.

      (Furriols and Bray, 2000)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      Scer\GAL4ptc-559.1, Su(H)ΔH.UAS has wing | distal phenotype, enhanceable by N55e11

      (Furriols and Bray, 2000)

      Scer\GAL4dpp.blk1, Su(H)ΔH.UAS has wing | distal phenotype, enhanceable by N55e11

      (Furriols and Bray, 2000)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The addition of N55e11 to Su(H)ΔH.Scer\UAS, Scer\GAL4dpp.blk1 or Su(H)ΔH.Scer\UAS, Scer\GAL4ptc-559.1 flies leads to a strong enhancement of the wing nicking phenotype.

      (Furriols and Bray, 2000)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Su(H)ΔH.Scer\UAS
      Su(H)ΔH.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (2)