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General Information
Symbol
Dmel\PhmP(29)
Species
D. melanogaster
Name
FlyBase ID
FBal0120693
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Imprecise excision of the Phmk07623 insertion has produced a deletion that removes 1309 bp of Phm genomic sequence. About 0.4kb of the original P{lacW} insertion also remains.

Caused by aberration
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

With very few exceptions homozygotes fail to hatch, those that do are nearly immobile and die within a few hours. Although failing to hatch, most embryos complete the large part of embryogenesis prior to their death. Little evidence for tissue disorganisation or morphological abnormality is seen. The G2 progeny of PhmP(29) adults rescued by PhmA5.hs have apparently normal central nervous systems (CNSs) about 3/4 of these embryos complete embryogenesis and hatch, about 3/5 reach pupal stages and about 1/5 complete metamorphosis. Puparium formation is often aberrant: puparia typically display a slight curvature, a failure to shorten normally, and a failure to evert anterior spiracles properly. The gas bubble fails to move anteriorly, leaving pupae in anterior position with abnormal posterior gas spaces. The majority of these non eclosing puparia die after completing pupation and proper eversion of the head wing and legs, but reveal no further adult differentiation, dying between stages P4ii and P7. Many animals also reaching the same stage display aberrant disc eversion, retention of larval mouthparts and imprecise elimination of apolysed tracheal cuticle. Almost none of the prepupae that fail to eclose differentiate past stage P7. Daily heatshock inductions do not increase the survival of these G2 animals.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (2)