FB2025_01 , released February 20, 2025
Allele: Dmel\MESK4EP1015
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General Information
Symbol
Dmel\MESK4EP1015
Species
D. melanogaster
Name
FlyBase ID
FBal0120758
Feature type
allele
Associated gene
Dmel\MESK4
Associated Insertion(s)
P{EP}MESK4EP1015
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Gene Disruption Project members, 2001-, Huang and Rubin, 2000)
Progenitor genotype
Associated Insertion(s)
P{EP}MESK4EP1015
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{EP}
Regulatory region(s)
UAS
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      Scer\GAL4hs.2sev/MESK4EP1015 is an enhancer of visible phenotype of Ras85DV12.sev

      (Huang and Rubin, 2000)
      Suppressor of
      Statement
      Reference

      Scer\GAL4hs.2sev/MESK4EP1015 is a suppressor of visible phenotype of ksr::torΔNksr.hs.sev

      (Huang and Rubin, 2000)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      Scer\GAL4hs.2sev/MESK4EP1015 is an enhancer of eye phenotype of Ras85DV12.sev

      (Huang and Rubin, 2000)
      Suppressor of
      Statement
      Reference

      Scer\GAL4hs.2sev/MESK4EP1015 is a suppressor of eye phenotype of ksr::torΔNksr.hs.sev

      (Huang and Rubin, 2000)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Strong suppressor of ksr::torΔNksr.hs.sev and moderate enhancer of Ras85DV12.sev, when expression is driven by Scer\GAL4hs.2sev.

      (Huang and Rubin, 2000)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      MESK41015
      MESK4EP1015
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0119464
      References (2)