Allele Avic\GFP^EGFP.Dpt

General Information
Symbol	Avic\GFP^EGFP.Dpt	Species	A. victoria
Name	Diptericin promoter construct of Leulier	FlyBase ID	FBal0121013
Feature type	allele	Associated gene	Avic\GFP

Allele class
Mutagen	in vitro construct - regulatory fusion
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class
Mutagen	in vitro construct - regulatory fusion (Leulier et al., 2000, Tzou et al., 2000)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype	Avic\GFP^EGFP.Mtk (Tzou et al., 2000)
Nature of the lesion	Statement Reference Construct: 2.2kb of Dpt upstream sequences drive Avic\GFP expression. (Leulier et al., 2000) Construct: The Mtk promoter sequences have been replaced by Dpt upstream sequences from -2266 to +42bp. (Tzou et al., 2000)
Carried in construct	P{Dpt-GFP.JM863} (Chiu et al., 2005, Foley and O'Farrell, 2003, Khush et al., 2002, Leulier et al., 2000, Tzou et al., 2000, Huh et al., 2007, Zaidman-Remy et al., 2006, McGettigan et al., 2005, Buchon et al., 2009, Stramer et al., 2008, Narbonne-Reveau et al., 2011, Galac and Lazzaro, 2011)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In

Detailed Description
	Statement Reference
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	Avic\GFP^Dpt.PL Avic\GFP^EGFP.Dpt
Name Synonym	Diptericin promoter construct of Leulier (Tzou et al., 2000, Leulier et al., 2000)
Secondary FlyBase IDs

References ( 12 )
Research paper	Galac and Lazzaro, 2011, Microbes Infect. 13(7): 673--683 Comparative pathology of bacteria in the genus Providencia to a natural host, Drosophila melanogaster. [FBrf0214338] Narbonne-Reveau et al., 2011, PLoS ONE 6(2): e17470 Lack of an antibacterial response defect in Drosophila toll-9 mutant. [FBrf0213211] Buchon et al., 2009, Cell Host Microbe 5(2): 200--211 Drosophila intestinal response to bacterial infection: activation of host defense and stem cell proliferation. [FBrf0206694] Stramer et al., 2008, EMBO Rep. 9(5): 465--471 Gene induction following wounding of wild-type versus macrophage-deficient Drosophila embryos. [FBrf0205363] Huh et al., 2007, J. Biol. Chem. 282(3): 2056--2068 The Drosophila inhibitor of apoptosis (IAP) DIAP2 is dispensable for cell survival, required for the innate immune response to gram-negative bacterial infection, and can be negatively regulated by the reaper/hid/grim family of IAP-binding apoptosis inducers. [FBrf0192423] Zaidman-Remy et al., 2006, Immunity 24(4): 463--473 The Drosophila amidase PGRP-LB modulates the immune response to bacterial infection. [FBrf0190838] Chiu et al., 2005, Dev. Biol. 288(1): 60--72 dUbc9 negatively regulates the Toll-NF-kappa B pathways in larval hematopoiesis and drosomycin activation in Drosophila. [FBrf0190102] McGettigan et al., 2005, Insect Biochem. Mol. Biol. 35(7): 741--754 Insect renal tubules constitute a cell-autonomous immune system that protects the organism against bacterial infection. [FBrf0187746] Foley and O'Farrell, 2003, Genes Dev. 17(1): 115--125 Nitric oxide contributes to induction of innate immune responses to gram-negative bacteria in Drosophila. [FBrf0155482] Khush et al., 2002, Curr. Biol. 12(20): 1728--1737 A ubiquitin-proteasome pathway represses the Drosophila immune deficiency signaling cascade. [FBrf0151852] Leulier et al., 2000, EMBO Rep. 1(4): 353--358 The Drosophila caspase Dredd is required to resist gram-negative bacterial infection. [FBrf0133276] Tzou et al., 2000, Immunity 13(5): 737--748 Tissue-specific inducible expression of antimicrobial peptide genes in Drosophila surface epithelia. [FBrf0132355]

Allele Avic\GFPEGFP.Dpt

Allele Avic\GFP^EGFP.Dpt