Allele Dmel\sra^EP3462

General Information
Symbol	Dmel\sra^EP3462	Species	D. melanogaster
Name		FlyBase ID	FBal0121655
Feature type	allele	Associated gene	Dmel\sra
Also Known As	EP(3)3462

Map ( GBrowse )	Untitled Document
Allele class
Mutagen	P-element activity
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class
Mutagen	P-element activity (Gene Disruption Project members, 2001-, Lukacsovich et al., 2001, Singh et al., 2001, Zhu et al., 2001)
Mutations Mapped to the Genome

Type Location Additional Notes References transposable element insertion site 3R:12,012,760..12,012,760 (Lukacsovich et al., 2001, Singh et al., 2001, Gene Disruption Project members, 2001-, Singh et al., 2005, Ejima et al., 2004, Zhu et al., 2001, Horner, 2006)
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference P{EP} insertion at position +104 (relative to the transcription start site), in the 5' UTR. Overexpression from the P{EP} element should drive expression of sequence from the sra antisense strand. (Ejima et al., 2004) P{EP} insertion in the 5' UTR, 55bp downstream of the putative transcription start site. (Zhu et al., 2001)
Caused by insertion	P{EP}sra^EP3462 (Lukacsovich et al., 2001, Singh et al., 2001, Gene Disruption Project members, 2001-, Singh et al., 2005, Ejima et al., 2004, Zhu et al., 2001, Horner, 2006)
Cytology
Phenotypic Data
Phenotypic Class
	fertile (Horner, 2006) viable (Horner, 2006)
Phenotype Manifest In

Detailed Description
	Statement Reference Expression of sra^EP3462 under the control of Scer\GAL4^unspecified does not stimulate ovulation in virgin females. (Ejima et al., 2004)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 1 )
Bloomington	17130 w¹¹¹⁸; P{EP}sra^EP3462 Bin1^EP3462
Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	EP(3)3462 (Zhu et al., 2001, Lukacsovich et al., 2001) nla^EP3462 sra^EP3462
Name Synonym
Secondary FlyBase IDs

References ( 8 )
Research paper	Singh et al., 2005, Dev. Biol. 278(1): 242--254 Sap18 is required for the maternal gene bicoid to direct anterior patterning in Drosophila melanogaster. [FBrf0183481] Ejima et al., 2004, Genetics 168(4): 2077--2087 Expression level of sarah, a homolog of DSCR1, is critical for ovulation and female courtship behavior in Drosophila melanogaster. [FBrf0182753] Lukacsovich et al., 2001, Genetics 157(2): 727--742 Dual-tagging Gene Trap of novel genes in Drosophila melanogaster. [FBrf0132344] Zhu et al., 2001, Dev. Genes Evol. 211(3): 109--117 Drosophila SAP18, a member of the Sin3/Rpd3 histone deacetylase complex, interacts with Bicoid and inhibits its activity. [FBrf0136855]
Supplementary material	Horner, 2006, Curr. Biol. 16(14): [FBrf0199124]
Personal communication to FlyBase	Gene Disruption Project members, 2001-, (Computer file) (Computer file) [FBrf0132177]
Abstract	Singh and Hanes, 2004, A. Dros. Res. Conf. 45: 336C Sin3-associated polypeptide p18 (Sap18), plays a role in Bicoid-dependent pattern formation in Drosophila. [FBrf0173483] Singh et al., 2001, A. Dros. Res. Conf. 42: 335B A screen for mutants of dSAP18, a co-repressor that interacts with Bicoid and inhibits its activity. [FBrf0133867]

Allele Dmel\sraEP3462

Allele Dmel\sra^EP3462