FB2022_02, released March 29, 2022

Allele: Dmel\mubEP3108

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General Information
Symbol
Dmel\mubEP3108
Species
D. melanogaster
Name
FlyBase ID
FBal0121676
Feature type
allele
Associated gene
Dmel\mub
Associated Insertion(s)
P{EP}mubEP3108
Carried in Construct
Key Links
Genomic Maps
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Gene Disruption Project members, 2001-, Levis, 2001.2.27, Lukacsovich et al., 2001)
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
transposable_element_insertion_site
3L:21,879,670..21,879,670 [-]
(Cao et al., 2008, Gene Disruption Project members, 2001-, Levis, 2001.2.27, Lukacsovich et al., 2001)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
       
      Progenitor genotype
      Cytology
      Nature of the lesion
      Statement
      Reference

      P{EP} insertion in a 5' exon.

      (Levis, 2001.2.27)
      Insertion components
      P{EP}mubEP3108
      Product class / Tool use(s)
      Regulatory region(s)
      UAS
      Encoded product / tool
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      exacerbates  Alzheimer's disease
      modeled by Hsap\APPAβ42.GMR.Tag:SS(rPENK)
      (Cao et al., 2008)
      ameliorates  Huntington's disease
      modeled by Hsap\HTTQ93.ex1.UAS
      (Cao et al., 2008)
      ameliorates  tauopathy
      modeled by Hsap\MAPTUAS.cWa
      (Cao et al., 2008)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression using Scer\GAL4ey.PU does not induce a rough eye phenotype.

      (Cao et al., 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      mub[+]/mubEP3108 is an enhancer of eye phenotype of Hsap\APPAβ42.GMR.Tag:SS(rPENK)

      (Cao et al., 2008)
      Suppressor of
      Statement
      Reference

      mubEP3108, Scer\GAL4GMR.PU is a suppressor of eye phenotype of Hsap\HTTQ93.ex1.UAS, Scer\GAL4GMR.PU

      (Cao et al., 2008)

      mubEP3108, Scer\GAL4ey.PU is a suppressor of eye phenotype of Hsap\MAPTUAS.cWa, Scer\GAL4ey.PU

      (Cao et al., 2008)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      EP(3)3108
      (Levis, 2001.2.27, Lukacsovich et al., 2001)
      mubEP3108
      Name Synonyms
      Secondary FlyBase IDs
        References (4)