FB2025_01 , released February 20, 2025
Allele: Dmel\groE47
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General Information
Symbol
Dmel\groE47
Species
D. melanogaster
Name
FlyBase ID
FBal0121749
Feature type
allele
Associated gene
Dmel\gro
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Stage 9 embryos derived from homozygous female germ-line clones show neuroblast hyperplasia and elevated mitotic activity in the developing neuroectoderm.

        (Orian et al., 2007)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Suppressed by
        Enhancer of
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        Sir205327a does not show a dominant synthetic lethal interaction with groE47.

        (Rosenberg and Parkhurst, 2002)

        The pair-rule phenotype of h26/h30 embryos is enhanced by one maternal copy of groE47. The enhancement of the pair-rule phenotype of h26/h30 embryos caused by one maternal copy of groE47 is reversed when one copy of CtBP03463 is also present maternally.

        (Phippen et al., 2000)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        groE47
        groe47
        (Domanitskaya and Schüpbach, 2012, Orian et al., 2007)
        Name Synonyms
        Secondary FlyBase IDs
          References (5)