Allele Scer\GAL4^GMR.PB

General Information
Symbol	Scer\GAL4^GMR.PB	Species	S. cerevisiae
Name	glass multimer reporter construct of Brogiolo	FlyBase ID	FBal0121984
Feature type	allele	Associated gene	Scer\GAL4

Allele class
Mutagen	FLPase
Recent Updates
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	FLPase (Brogiolo et al., 2001, Rintelen et al., 2001, Reiling and Hafen, 2004)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype	Scer\GAL4^Scer\FRT.GMR (Brogiolo et al., 2001, Rintelen et al., 2001, Reiling and Hafen, 2004)
Nature of the lesion	Statement Reference Construct: Scer\FRT has been excised, so that GMR sequences drive expression of Scer\GAL4. (Brogiolo et al., 2001)
Carried in construct	P{GMR-GAL4(FRT-)} (Rintelen et al., 2001, Brogiolo et al., 2001, Reiling and Hafen, 2004, Junger et al., 2003, Nairz et al., 2006, Schwinkendorf and Gallant, 2009, Honegger et al., 2008)
Cytology
Phenotypic Data
Phenotypic Class
	decreased cell number \| somatic clone, with B4^{Scer\UAS.T:Ivir\HA1} (Wittwer et al., 2005) decreased cell size \| cell non-autonomous \| somatic clone, with B4^{Scer\UAS.T:Ivir\HA1} (Wittwer et al., 2005) decreased cell size \| somatic clone, with chrb^Scer\UAS.cRa (Reiling and Hafen, 2004) decreased cell size \| somatic clone, with ImpL2^Scer\UAS.cHa (Honegger et al., 2008) decreased cell size \| somatic clone, with scyl^EP22.1 (Reiling and Hafen, 2004) visible, with Hsap\FOXO3^TM.Scer\UAS (Junger et al., 2003) visible, with InR^Scer\UAS.cHa (Brogiolo et al., 2001)
Phenotype Manifest In
	eye, with InR^Scer\UAS.cHa (Brogiolo et al., 2001) eye \| somatic clone, with Hsap\FOXO3^TM.Scer\UAS (Junger et al., 2003) eye photoreceptor cell \| cell non-autonomous \| somatic clone, with B4^{Scer\UAS.T:Ivir\HA1} (Wittwer et al., 2005) ommatidium, with dm^{MB2A.Scer\UAS.T:HA1} (Schwinkendorf and Gallant, 2009) ommatidium, with dm^{WT.Scer\UAS.T:Ivir\HA1} (Schwinkendorf and Gallant, 2009) ommatidium, with dm^{ΔMB2.Scer\UAS.T:HA1} (Schwinkendorf and Gallant, 2009) ommatidium, with dm^{ΔMB3.Scer\UAS.T:HA1} (Schwinkendorf and Gallant, 2009) ommatidium \| somatic clone, with mir-278^{KN447.Scer\UAS} (Nairz et al., 2006)
Detailed Description
	Statement Reference
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Statement Reference InR^Scer\UAS.cHa, Scer\GAL4^GMR.PB has visible phenotype, suppressible by Df(3L)AC1 (Brogiolo et al., 2001)
Phenotype Manifest In
Suppressed by
Statement Reference InR^Scer\UAS.cHa, Scer\GAL4^GMR.PB has eye phenotype, suppressible by Df(3L)AC1 (Brogiolo et al., 2001)
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	Scer\GAL4^GMR.PB
Name Synonym	glass multimer reporter construct of Brogiolo (Brogiolo et al., 2001)
Secondary FlyBase IDs

References ( 8 )
Research paper	Schwinkendorf and Gallant, 2009, Gene 436(1-2): 90--100 The conserved Myc box 2 and Myc box 3 regions are important, but not essential, for Myc function in vivo. [FBrf0207648] Honegger et al., 2008, J. Biol. 7(3): 10 Imp-L2, a putative homolog of vertebrate IGF-binding protein 7, counteracts insulin signaling in Drosophila and is essential for starvation resistance. [FBrf0204716] Nairz et al., 2006, Dev. Biol. 291(2): 314--324 Overgrowth caused by misexpression of a microRNA with dispensable wild-type function. [FBrf0190148] Wittwer et al., 2005, Dev. Cell 8(6): 817--827 Susi, a negative regulator of Drosophila PI3-kinase. [FBrf0187416] Reiling and Hafen, 2004, Genes Dev. 18(23): 2879--2892 The hypoxia-induced paralogs Scylla and Charybdis inhibit growth by down-regulating S6K activity upstream of TSC in Drosophila. [FBrf0180258] Junger et al., 2003, J. Biol. 2(3): 20 The Drosophila Forkhead transcription factor FOXO mediates the reduction in cell number associated with reduced insulin signaling. [FBrf0162177] Brogiolo et al., 2001, Curr. Biol. 11(4): 213--221 An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control. [FBrf0134520] Rintelen et al., 2001, Proc. Natl. Acad. Sci. U.S.A. 98(26): 15020--15025 PDK1 regulates growth through Akt and S6K in Drosophila. [FBrf0141724]

Allele Scer\GAL4GMR.PB

Allele Scer\GAL4^GMR.PB