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General Information
Symbol
Dmel\Eip93FUAS.cLa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Lee
FlyBase ID
FBal0123173
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-E93
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference
Sequencing indicates that the initial AUG codon is mutated in this line.
UAS sequences drive expression of the Eip93F full length open reading frame.
Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
When embryos are heat shocked to induce Scer\GAL4hs.PB during embryogenesis widespread cell death occurs. When expression is driven by Scer\GAL4h-1J3, cell death occurs in stripes in the embryos, which subsequently die at the end of embryogenesis with head defects and fusion/deletion of alternate denticle belts.
When Eip93FScer\UAS.cLa is driven by Scer\GAL4vg.PM, all animals die at the start of pupal development. Large amounts of ectopic cell death is seen in the wing and hinge regions of the wing disc. Wing disc morphogenesis is defective, such that the wing does not elongate and appears to fold back on itself. Animals die soon after head eversion during metamorphosis and exhibit defects in the presumptive adult notum and wing.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
NOT suppressed by
Additional Comments
Genetic Interactions
Statement
Reference
Cell death phenotype is not suppressed by removal of rpr, W and grim (i.e. Df(3L)H99), though the remaining cell death does not show the nuclear hallmarks or programmed cell death.
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
Eip93FScer\UAS.cLa
Eip93FUAS.cLa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Lee
Secondary FlyBase IDs
    References (3)