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General Information
Symbol
Dmel\Vha16-1EP2372
Species
D. melanogaster
Name
FlyBase ID
FBal0123258
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Insertion components
P{EP}Vha16-1EP2372
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Vha16-1EP2372/+ flies show starvation resistance (prolonged survival under food-deprived conditions) compared to wild type. Around 60% of Vha16-1EP2372/+ flies show diminished midgut acidity (compared to 19% in controls). Vha16-1EP2372/+ flies have further diminished midgut acidity when fed acetazolamide (similar to wild type). Vha16-1EP2372/+ flies have a shortened lifespan compared to wild type under normal conditions.

Mutant larvae expressing Vha16EP2372 under the control of Scer\GAL4elav-C155 have reduced or abnormal synapses.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Rescued by
Comments

Expression of Vha16-1Scer\UAS.cLa driven by Scer\GAL4NP3270 rescues midgut acidity levels in Vha16-1EP2372/+ flies.

Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
EP2372EP2372
Vha16-1EP2372
Vha16EP2372
Name Synonyms
Secondary FlyBase IDs
    References (3)