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General Information
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| Symbol | Dmel\Cdc42L89.Scer\UAS | Species | D. melanogaster |
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| Name | | FlyBase ID | FBal0123294 |
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| Feature type | allele | Associated gene | Dmel\Cdc42 |
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| Allele class | |
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| Mutagen | in vitro construct - regulatory fusion |
Recent Updates
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| Description |
What does this section display?
This section contains items that were added to this record for each release.
It currently only tracks new links between this FlyBase report and other
FlyBase data classes (e.g. genes, references, stocks) or controlled
vocabulary terms (e.g. GO, anatomy terms).
What does this section not display?
This section does not currently display links that were removed or gene model changes.
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| FB2013_03 |
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| FB2013_02 |
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| All updates |
Click here to see a list of all updates to this record from FB2010_08 and on.
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Nature of the Allele
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| Allele class | |
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| Mutagen | |
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| Mutations Mapped to the Genome |
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| Associated Sequence Data |
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DDBJ
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EMBL
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GenBank |
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| UniProtKB/Swiss-Prot | |
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| UniProtKB/TrEMBL | |
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| Progenitor genotype | |
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| Nature of the lesion | Amino acid replacement: S89L. Construct: A dominant negative form of Cdc42 is expressed under the control of Scer\UAS regulatory sequences. |
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| Carried in construct | |
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| Cytology | |
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Phenotypic Data
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Phenotypic Class
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Phenotype Manifest In
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Detailed Description
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| Expression of Cdc42L89.Scer\UAS driven by Scer\GAL4ptc-559.1 results in loss or stunting of epidermal hairs. When Cdc42L89.Scer\UAS is driven by Scer\GAL4Bx-MS1096, occasional multiple (but still stunted) wing hairs are seen. A reduction in wing size, formation of ectopic vein tissue and wing margin phenotypes. A strong bristle loss phenotype is seen in the wing margin which precludes observation of the width of the margin stripe. Small outgrowths in the wing surface are also seen. |
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External Data
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| Linkouts | |
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Interactions
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Phenotypic Class
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Enhanced by |
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NOT Enhanced by |
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Suppressed by |
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NOT suppressed by |
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Phenotype Manifest In
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Additional Comments
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Genetic Interactions
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Xenogenetic Interactions
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Complementation & Rescue Data
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| Comments | |
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Stocks
( 2 ) |
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| Bloomington | |
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| Kyoto | |
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Notes on Origin
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Discoverer
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External Crossreferences & Linkouts
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| Other Crossreferences |
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| Linkouts |
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Synonyms & Secondary IDs
( 2 ) |
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| Reported As |
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| Symbol Synonym | |
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| Name Synonym | |
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| Secondary FlyBase IDs |
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References
( 3 ) |
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| Research paper | - Zhu et al., 2005, Genetics 170(2): 767--777
- A screen for genes that influence fibroblast growth factor signal transduction in Drosophila. [FBrf0187664]
- Baron et al., 2000, Mol. Gen. Genet. 264(1-2): 98--104
- Multiple roles of the Dcdc42 GTPase during wing development in Drosophila melanogaster. [FBrf0129723]
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| Personal communication to FlyBase | - Luo, 2001.5.2, Luo constructs and insertions.
- Luo constructs and insertions. [FBrf0136038]
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