Hearts from flies expressing Scer\GAL4tin.CΔ4>phlAct.Scer\UAS show reduced end-diastolic dimensions relative to controls. The transgenic hearts display myofiber disarray and increased heart wall thickness compared with controls. The number of cardiomyocytes is similar in the hearts from the transgenic flies to that of wild-type. Compared with controls, the transgenic hearts show an increase in cardiomyocyte ploidy, suggesting abnormal endoreplication.
Expression of phlAct.Scer\UAS in the midgut, under the control of Scer\GAL4esg-NP7397 results in the generation of many new midgut cells, including enterocyte-like cells.
Expression of phlAct.Scer\UAS under the control of Scer\GAL4ey.PB can result in homeotic transformation of the eye to antenna. The ectopic antenna has all segments including the arista and is oriented similarly to the endogenous antenna.