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General Information
Symbol
Dmel\kaypan-Ala.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0125001
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-fospanAla
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference
UASt drives expression of a mutated kay cDNA (carries the amino acid replacements S388A, T449A, T460A, S495A, T542A, T562A, T584A, T89A and T93A).
Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
ameliorates  cancer
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
The expression of kaypan-Ala.Scer\UAS under the control of Scer\GAL4Bx-MS1096 does not result in any obvious size or viability defects in third instar larval wing discs, as compared to controls.
Half of wing discs with wounds in the posterior compartment show normal wound healing when kaypan-Ala.Scer\UAS is overexpressed under the control of Scer\GAL4en-e16E.
kaypan-Ala.Scer\UAS when driven by Scer\GAL469B, gives rise to a strong thoracic cleft at the dorsal midline. When kaypan-Ala.Scer\UAS is driven by Scer\GAL4en-e16E, loss of wing vein material is seen.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
NOT Suppressor of
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
The co-expression of kaypan-Ala.Scer\UAS suppresses the tumor phenotype and tissue disorganization resulting from the expression of dlg1HMS01954 under the control of Scer\GAL4Bx-MS1096.
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
kaypan-Ala.Scer\UAS
kaypan-Ala.UAS
Name Synonyms
Secondary FlyBase IDs
    References (4)