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General Information
Symbol
Dmel\kayN-Ala.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0125003
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference
UASt drives expression of a mutated kay cDNA (carries the amino acid replacements T89A and T93A).
Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
Only 35% of wing discs with wounds in the posterior compartment show normal wound healing when kayN-Ala.Scer\UAS (a mutant that cannot be phosphorylated by the JNK pathway) is overexpressed under the control of Scer\GAL4en-e16E.
kayN-Ala.Scer\UAS when driven by Scer\GAL469B, gives rise to a thoracic cleft at the dorsal midline. When kayN-Ala.Scer\UAS is driven by Scer\GAL4en-e16E, no effect is seen on wing vein development.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Clonal co-expression of kayN-Ala.Scer\UAS partially suppresses the lethality and developmental delay seen in larvae with scrib1 mutant eye-antennal disc clones expressing Ras85DV12.Scer\UAS under the control of Scer\GAL4Act.PU, and suppresses the invasive infiltration of the ventral nerve cord exhibited by cells of these clones, although the tumor mass is not significantly decreased. Clonal co-expression of kayN-Ala.Scer\UAS partially suppresses the defective photoreceptor differentiation seen in scrib1 mutant eye-antennal disc clones expressing Ras85DV12.Scer\UAS under the control of Scer\GAL4Act.PU.
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
kayN-Ala.Scer\UAS
kayN-Ala.UAS
Name Synonyms
Secondary FlyBase IDs
    References (3)