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General Information
Symbol
Dmel\fafEP3520
Species
D. melanogaster
Name
FlyBase ID
FBal0125065
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
EP(3)3520
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Insertion components
P{EP}fafEP3520
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
Expression of fafEP3520 under the control of Scer\GAL4Ccap.PP results in subtle defects in small portions of the central nervous system arbor in larvae. Expression of fafEP3520 under the control of Scer\GAL4Ccap.PP results in the loss of adult-specific neurite projections.
When fafEP3520 is driven by Scer\GAL4elav-C155, a marked expansion in the size and complexity is seen in the synapses. There is an increase in both the number of synaptic boutons and in the synaptic span. There is also an increase in the number of synaptic branches. When the evoked excitatory junctional potentials (EJPs) of fafEP3520, Scer\GAL4elav-C155 embryos are examined, a marked reduction is seen in their amplitudes. A large decrease in quantal content is also seen, and the frequency of spontaneous mEJPs is also reduced.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Statement
Reference
Other
Phenotype Manifest In
Suppressor of
Statement
Reference
fafEP3520 is a suppressor of eye phenotype of Dcp-1UAS.cKa, Scer\GAL4GMR.PF
Additional Comments
Genetic Interactions
Statement
Reference
fafEP3520 enhances the rough eye phenotype seen when Dcp-1Scer\UAS.cKa (insertion line P{UAS-Dcp-1.K}19-2) is expressed under the control of Scer\GAL4GMR.PF.
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
fafEP3520
Name Synonyms
Secondary FlyBase IDs
    References (5)