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General Information
Symbol
Dmel\eyΔHD.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0125070
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference
UAS sequences drive expression of a mutated form of the E10 ey cDNA. This cDNA has had a BclI/VspI fragment deleted removing the HD domain.
Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
eyScer\UAS.ΔHD; Scer\GAL4dpp.blk1 adults flies have ectopic eyes on various appendages. Expressivity of this phenotype varies depending on the P{UAS-ey.ΔHD} insertion used, correlating with the level of expression from the insertion.
Expression of eyScer\UAS.ΔHD when driven by Scer\GAL4dpp.blk1 leads to ectopic eyes. The addition of ey2 or eyJ5.71 does not affect this phenotype.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Statement
Reference
NOT Suppressor of
Statement
Reference
Phenotype Manifest In
Suppressor of
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference
Animals co-expressing eyΔHD.Scer\UAS and AntpScer\UAS.cBa under the control of Scer\GAL4ey-OK107 show lethality such that few pupae are obtained. The few escapers show partial rescue of the eye loss caused by expression of AntpScer\UAS.cBa under the control of Scer\GAL4ey-OK107.
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Expression of eyΔHD.Scer\UAS under the control of Scer\GAL4ey-OK107 partially rescues the eye defects, but does not rescue the mushroom body or central complex defects, of eyEH/eyOK107-16 mutants. Expression of eyΔHD.Scer\UAS under the control of Scer\GAL4ey-OK107 rescues the mushroom body and central complex defects, and partially rescues the eye defects, of eyJD/eyOK107-16 mutants.
eyScer\UAS.ΔHD (driven by Scer\GAL4ey.PH) rescues ey2 at an even higher efficiency than wild-type ey.
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
eyScer\UAS.ΔHD
eyΔHD.Scer\UAS
eyΔHD.UAS
Name Synonyms
Secondary FlyBase IDs
    References (5)