FB2025_01 , released February 20, 2025
Allele: Scer\GAL4c105
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General Information
Symbol
Scer\GAL4c105
Species
S. cerevisiae
Name
FlyBase ID
FBal0126485
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
P{GawB}c105c105
Carried in Construct
Also Known As
c105, C105-GAL4
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{GawB}c105c105
    Cytology
    Description
    Allele components
    Component
    Use(s)
    Inserted element
    P{GawB}
    Encoded product / tool
    GAL4
    Mutations Mapped to the Genome
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        distribution deduced from reporter (Gal4 UAS)
        Stage
        Tissue/Position (including subcellular localization)
        Reference
        adult stage
        adult ellipsoid body ring neuron R1
        (Martín-Peña et al., 2014, Chen et al., 2012, Baker et al., 2007, Renn et al., 1999)
        large field neuron | subset
        (Renn et al., 1999)
        ellipsoid body | restricted

        Comment: inner part of ellipsoid body

        (Baker et al., 2007, Renn et al., 1999)
        adult protocerebrum | lateral
        (Baker et al., 2007)
        adult ellipsoid body ring neuron R1 | subset
        (Bridi et al., 2019)
        Additional Information
        Statement
        Reference

        ScerGAL4c105 drives expression in a total number of around 6 ring neurons R1 after eclosion and in about 8 neurons per hemisphere after 7 days. Labeled neurons co-express ScerGAL80ple.PK.

        (Martín-Peña et al., 2014)

        Expression of ScerGAL4c105 is seen in approximately 7 cells in each brain hemisphere that project to the bulb (or 'lateral triangle') of the central complex before bifurcating to project to the posterior ring of the ellipsoid body and to descend through the central brain.

        (Baker et al., 2007)

        Adult expression is observed in six-ten R1 ring neurons, with cell bodies lateral to the central complex, that arborize in the inner domain of the ellipsoid body and project to the lateral triangle.

        (Renn et al., 1999)
         
        Marker for
        adult ellipsoid body ring neuron
        (Renn et al., 1999)
        ellipsoid body
        (Renn et al., 1999)
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Inhibition (using shi1.UAS at 32[o]C) of Scer\GAL4c105 cells in adults does not affect startle-induced climbing behavior, compared to controls.

        Thermogenetic activation (using TrpA1UAS.(B).cKa at 32[o]C) of Scer\GAL4c105 cells in adults does not affect startle-induced climbing behavior, compared to controls.

        (Sun et al., 2018)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        Scer\GAL4c105
        Name Synonyms
        Secondary FlyBase IDs
          References (19)