FlyBase Allele Report: Hsap\MAPT[V337M.UAS]

General Information

Symbol

Hsap\MAPT^V337M.UAS

Species

H. sapiens

Name

FlyBase ID

FBal0126525

Feature type

allele

Associated gene

Hsap\MAPT

Associated Insertion(s)

Carried in Construct

P{UAS-Hsap\MAPT.V337M}

Also Known As

UAS-tau^V337M, Tau^V337M, UAS-V337M tau

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

in vitro construct - regulatory fusion

(Wittmann et al., 2001)

in vitro construct - coding region fusion

(Wittmann et al., 2001)

Mutations Mapped to the Genome

Type

Location

Additional Notes

References

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Progenitor genotype

Carried in construct

P{UAS-Hsap\MAPT.V337M}

Cytology

Nature of the lesion

Statement

Reference

UAS regulatory sequences drive expression of a mutant form of Hsap\MAPT (carries the amino acid replacement V337M).

(Wittmann et al., 2001)

Allele components

Product class / Tool use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Hsap\MAPT

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 1 )

Disease

Evidence

References

model of Alzheimer's disease

CEA

(Haddadi et al., 2016, Shulman et al., 2011)

model of tauopathy

CEA

(Aqsa and Sarkar, 2021, Nisha and Sarkar, 2021, Pragati et al., 2020, Hsieh et al., 2019, Mao et al., 2017, Bernstein et al., 2016, Shulman et al., 2014, Xiong et al., 2013, Kosmidis et al., 2010, Shulman and Feany, 2003, Wittmann et al., 2001)

model of neurodegenerative disease

CEA

(Khurana et al., 2006)

model of frontotemporal dementia

CEA

(Pragati et al., 2020)

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

model of tauopathy

is ameliorated by HDAC6^KO

(Xiong et al., 2013)

is exacerbated by wdb^EP3559

(Shulman and Feany, 2003)

is ameliorated by stg^UAS.cNa

(Shulman and Feany, 2003)

is exacerbated by cher^EP3715

(Shulman and Feany, 2003)

is exacerbated by Fem-1^EP2504

(Shulman and Feany, 2003)

is ameliorated by par-1^{N1S.UASp.mGFP6}

(Shulman and Feany, 2003)

is exacerbated by aop^EP2500

(Shulman and Feany, 2003)

is exacerbated by dally^EP581

(Shulman and Feany, 2003)

is ameliorated by Gbs-70E^EP3518

(Shulman and Feany, 2003)

is exacerbated by CG7231^EP2510

(Shulman and Feany, 2003)

is exacerbated by Tao^EP1455

(Shulman and Feany, 2003)

is ameliorated by stg^EP3432

(Shulman and Feany, 2003)

is exacerbated by Atx2^EP3145

(Shulman and Feany, 2003)

is ameliorated by stg^EP1213

(Shulman and Feany, 2003)

is ameliorated by stg^EP3426

(Shulman and Feany, 2003)

is ameliorated by Diap1^EP3308

(Shulman and Feany, 2003)

is ameliorated by wun^EP2208

(Shulman and Feany, 2003)

is exacerbated by EP639^EP2437

(Shulman and Feany, 2003)

is ameliorated by twe^EP613

(Shulman and Feany, 2003)

is exacerbated by cdi^EP3319

(Shulman and Feany, 2003)

is ameliorated by fry⁰²²⁴⁰

(Shulman and Feany, 2003)

is exacerbated by fry^EP326

(Shulman and Feany, 2003)

is exacerbated by Orct2^EP1072

(Shulman and Feany, 2003)

is ameliorated by CG3735^EP2311

(Shulman and Feany, 2003)

is exacerbated by garz^EP2028

(Shulman and Feany, 2003)

is exacerbated by Fmr1^EP3517

(Shulman and Feany, 2003)

is exacerbated by Diap1^j5C8

(Shulman and Feany, 2003)

is ameliorated by Orct2^EP3569

(Shulman and Feany, 2003)

is exacerbated by Diap1^SL

(Shulman and Feany, 2003)

is exacerbated by EP2190^EP2190

(Shulman and Feany, 2003)

is exacerbated by chb^EP3403

(Shulman and Feany, 2003)

is ameliorated by par-1^EP899

(Shulman and Feany, 2003)

is ameliorated by αTub84B^K40Q

(Mao et al., 2017)

is ameliorated by αTub84B^K40R

(Mao et al., 2017)

is ameliorated by Myc^JF01761

(Pragati et al., 2020)

is exacerbated by SmB^HM05097

(Hsieh et al., 2019, Shulman et al., 2014)

is exacerbated by SmB^KK102021

(Hsieh et al., 2019, Shulman et al., 2014)

is exacerbated by SmB^{MI07584-GFSTF.0}

(Hsieh et al., 2019)

is exacerbated by SmD2^GD7741

(Hsieh et al., 2019)

is exacerbated by SmD2^HMC03839

(Hsieh et al., 2019)

is exacerbated by SmE^GD13663

(Hsieh et al., 2019)

is exacerbated by SmE^HMS00074

(Hsieh et al., 2019)

is exacerbated by snRNP-U1-70K^GD13212

(Hsieh et al., 2019)

is exacerbated by snRNP-U1-70K^HMS00274

(Hsieh et al., 2019)

is exacerbated by snRNP-U1-C^GD11660

(Hsieh et al., 2019)

is exacerbated by snRNP-U1-C^HMS00137

(Hsieh et al., 2019)

is exacerbated by snf^J210

(Hsieh et al., 2019)

is exacerbated by Fit1^GD17050

(Shulman et al., 2014)

is ameliorated by Fit1^UAS.GFP

(Shulman et al., 2014)

is ameliorated by Fit2^EY08530

(Shulman et al., 2014)

is exacerbated by Lar^GD14391

(Shulman et al., 2014)

is exacerbated by Lar^HMS00822

(Shulman et al., 2014)

is ameliorated by SmB^UASp.Venus

(Shulman et al., 2014)

is exacerbated by bru1^GD8699

(Shulman et al., 2014)

is ameliorated by bru1^UASp.cSa

(Shulman et al., 2014)

is exacerbated by cindr^{dsRNA.PC.PD.UAS}

(Shulman et al., 2014)

is exacerbated by cindr^dsRNA.PC.UAS

(Shulman et al., 2014)

is exacerbated by cindr^dsRNA.UAS

(Shulman et al., 2014)

is exacerbated by dop^GD11940

(Shulman et al., 2014)

is exacerbated by dop^GL00220

(Shulman et al., 2014)

is exacerbated by dop^JF02778

(Shulman et al., 2014)

is ameliorated by oxt^G4946

(Shulman et al., 2014)

is exacerbated by oxt^dsRNA.UAS

(Shulman et al., 2014)

is ameliorated by scb^EY02806

(Shulman et al., 2014)

is ameliorated by scb^EY10270

(Shulman et al., 2014)

is exacerbated by scb^JF02696

(Shulman et al., 2014)

is exacerbated by scb^PB.UAS

(Shulman et al., 2014)

is exacerbated by Amph^A.UAS

(Bernstein et al., 2016)

is exacerbated by Hsap\CELF1^UAS.cdHa

(Bernstein et al., 2016)

is exacerbated by Rbp^MB02027

(Bernstein et al., 2016)

is ameliorated by Set^EY09821

(Bernstein et al., 2016)

is exacerbated by msn^HMJ02084

(Bernstein et al., 2016)

is exacerbated by bru1^BG01566

(Bernstein et al., 2016)

is exacerbated by msn^JF03219

(Bernstein et al., 2016)

is ameliorated by bru2^G5819

(Bernstein et al., 2016)

is ameliorated by ema^HMC03234

(Bernstein et al., 2016)

is ameliorated by glob1^HMS01556

(Nisha and Sarkar, 2021)

is exacerbated by glob1^UAS.cYa

(Nisha and Sarkar, 2021)

is ameliorated by Act5C^G0010

(Fulga et al., 2007)

is exacerbated by Act5C^UAS.GFP

(Fulga et al., 2007)

is ameliorated by tsr^{UAS.Tag:polyHis}

(Fulga et al., 2007)

model of Alzheimer's disease

is ameliorated by Glut1^d05758

(Shulman et al., 2011)

is ameliorated by sli^UAS.cBa

(Shulman et al., 2011)

is exacerbated by sli^GD5822

(Shulman et al., 2011)

is ameliorated by fne^KK108902

(Shulman et al., 2011)

is exacerbated by fne^UAS.cCa

(Shulman et al., 2011)

is exacerbated by β-Spec^dsRNA.UAS

(Shulman et al., 2011)

is exacerbated by Hs6st^{dsRNA.IR.UAS.K}

(Shulman et al., 2011)

is exacerbated by dlg1^GD4689

(Shulman et al., 2011)

model of frontotemporal dementia

is ameliorated by Myc^JF01761

(Pragati et al., 2020)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

This allele represents a human variant implicated in disease.

(Wittmann et al., 2001)

MAPT:p.Val654Met

(FlyBase curators, 2019-)

Variants Synonym(s)

MAPT:p.Val337Met

Associated human disease model(s)

External database links

ClinVar: MAPT_14252

Comments concerning this variant

Phenotypic Data

Phenotypic Class

abnormal cell shape | larval stage, with Scer\GAL4^GMR.PU

(Nisha and Sarkar, 2021)

abnormal cell shape | pupal stage, with Scer\GAL4^GMR.PU

(Nisha and Sarkar, 2021)

abnormal locomotor behavior | adult stage | progressive, with Scer\GAL4^elav.PLu

(Nisha and Sarkar, 2021)

abnormal memory | adult stage, with Scer\GAL4^c739

(Haddadi et al., 2016)

abnormal neuroanatomy, with Scer\GAL4^elav.PU

(Kosmidis et al., 2010)

abnormal neuroanatomy | adult stage, with Scer\GAL4^elav.PLu

(Nisha and Sarkar, 2021)

abnormal neuroanatomy | third instar larval stage, with Scer\GAL4^elav.PU

(Mao et al., 2017)

abnormal size | adult stage, with Scer\GAL4^GMR.PU

(Hsieh et al., 2019)

decreased size | adult stage, with Scer\GAL4^elav.PLu

(Nisha and Sarkar, 2021)

decreased size | adult stage, with Scer\GAL4^GMR.PU

(Nisha and Sarkar, 2021)

increased cell death | larval stage, with Scer\GAL4^GMR.PU

(Nisha and Sarkar, 2021)

short lived, with Scer\GAL4^elav.PLu

(Nisha and Sarkar, 2021)

short lived, with Scer\GAL4^elav-C155

(Haddadi et al., 2016)

visible, with Scer\GAL4^elav.PLu

(Shulman and Feany, 2003)

visible, with Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

visible | adult stage, with Scer\GAL4^GMR.PU

(Nisha and Sarkar, 2021, Hsieh et al., 2019, Shulman et al., 2011)

Phenotype Manifest In

adult brain, with Scer\GAL4^elav.PLu

(Nisha and Sarkar, 2021)

adult brain, with Scer\GAL4^unspecified

(Wittmann et al., 2001)

adult Kenyon cell, with Scer\GAL4^elav.PLu

(Nisha and Sarkar, 2021)

adult mushroom body, with Scer\GAL4^elav.PU

(Kosmidis et al., 2010)

axon | adult stage, with Scer\GAL4^elav.PLu

(Nisha and Sarkar, 2021)

cytoplasmic microtubule | third instar larval stage, with Scer\GAL4^C57

(Mao et al., 2017)

embryonic/larval neuromuscular junction | larval stage, with Scer\GAL4^elav.PU

(Xiong et al., 2013)

embryonic/larval somatic muscle cell | third instar larval stage, with Scer\GAL4^C57

(Mao et al., 2017)

eye, with Scer\GAL4^elav.PLu

(Shulman and Feany, 2003)

eye, with Scer\GAL4^GMR.PF

(Yeh et al., 2010, Mallik and Lakhotia, 2009, Fulga et al., 2007, Khurana et al., 2006, Yang et al., 2005, Shulman and Feany, 2003)

eye, with Scer\GAL4^GMR.PU

(Nisha and Sarkar, 2021, Hsieh et al., 2019)

eye | adult stage, with Scer\GAL4^GMR.PU

(Shulman et al., 2011)

eye | pupal stage, with Scer\GAL4^GMR.PU

(Nisha and Sarkar, 2021)

eye disc, with Scer\GAL4^GMR.PU

(Nisha and Sarkar, 2021)

eye photoreceptor cell, with Scer\GAL4^GMR.PF

(Yang et al., 2005)

eye photoreceptor cell | pupal stage, with Scer\GAL4^GMR.PU

(Nisha and Sarkar, 2021)

interommatidial bristle, with Scer\GAL4^GMR.PU

(Nisha and Sarkar, 2021)

lens, with Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

lobe system of adult mushroom body, with Scer\GAL4^elav.PLu

(Nisha and Sarkar, 2021)

macrochaeta, with Scer\GAL4^Eq

(Yeh et al., 2010)

microtubule, with Scer\GAL4^C57

(Xiong et al., 2013)

mitochondrion | larval stage, with Scer\GAL4^GMR.PU

(Nisha and Sarkar, 2021)

NMJ bouton | increased number | third instar larval stage, with Scer\GAL4^elav.PU

(Mao et al., 2017)

NMJ bouton | larval stage, with Scer\GAL4^elav.PU

(Xiong et al., 2013)

ommatidium, with Scer\GAL4^elav.PLu

(Shulman and Feany, 2003)

ommatidium, with Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

ommatidium, with Scer\GAL4^GMR.PU

(Nisha and Sarkar, 2021)

ommatidium | pupal stage, with Scer\GAL4^GMR.PU

(Nisha and Sarkar, 2021)

rhabdomere of eye photoreceptor cell | adult stage, with Scer\GAL4^GMR.PU

(Nisha and Sarkar, 2021)

rhabdomere of eye photoreceptor cell | pupal stage, with Scer\GAL4^GMR.PU

(Nisha and Sarkar, 2021)

sensory organ cell, with Scer\GAL4^Eq

(Yeh et al., 2010)

Detailed Description

Statement

Reference

The expression of Hsap\MAPT^V337M.UAS under the control of Scer\GAL4^GMR.PU results in pupal and adult eye defects; adults exhibit ommatidial fusion, deformed arrangement of the eye bristle lattice, irregular arrays of ommatidia and rhabdomeres, tissue vacuoles, reduced eye size and roughening of the eye surface; pupae display disruption of the hexagonal lattice of ommatidia and trapezoid arrangement of the rhabdomeres, as well as elongated photoreceptor cells that juxtapose or are fused with photoreceptor cells of neighboring ommatidia. The larval eye discs exhibit distorted cellular morphology, mitochondrial aggregation (MitoTracker) and increased apoptosis.

The expression of Hsap\MAPT^V337M.UAS under the control of Scer\GAL4^elav.PLu causes a progressive decrease in climbing activity, adult brain vacuolization and degeneration of the mushroom body axonal projections, leading to the smaller mushroom body lobes.

(Nisha and Sarkar, 2021)

Expression of Hsap\MAPT^V337M.UAS under the control of Scer\GAL4^GMR.PU results in reduced eye size and a roughened eye surface, compared to controls.

(Hsieh et al., 2019)

Expression of Hsap\MAPT^{V337M.Scer\UAS} under the control of Scer\GAL4^C57 leads to significantly reduced density of perinuclear microtubules (MTs) in third instar larval muscles, with sparser and shorter fibers compared to controls. Scer\GAL4^elav.PU-driven expression results in excess of satellite boutons at larval neuromuscular junctions.

(Mao et al., 2017)

Expression of Hsap\MAPT^{V337M.Scer\UAS} driven pan-neuronally by Scer\GAL4^elav-C155 leads to a significantly shortened lifespan compared to control flies; shortened lifespan is not as severe (significantly longer) than seen with expression of Hsap\MAPT^Scer\UAS.cWa or Hsap\MAPT[R406W.Scer\UAS]. Scer\GAL4^elav-C155>Hsap\MAPT^{V337M.Scer\UAS} flies show significant changes in the activity of antioxidant enzymes.

Expression of Hsap\MAPT^{V337M.Scer\UAS} driven in mushroom bodies by Scer\GAL4^c739 leads to significant impairment in middle-term and long-term olfactory memory compared to controls.

(Haddadi et al., 2016)

Expression of Hsap\MAPT^{V337M.Scer\UAS} under the control of Scer\GAL4^C57 results in microtubule fragmentation and reduced perinuclear microtubule density in the muscles.

Expression of Hsap\MAPT^{V337M.Scer\UAS} under the control of Scer\GAL4^elav.PU results in a significant increase in the number of satellite boutons at the neuromuscular junction (NMJ) and a significant decrease in average NMJ length compared to controls.

(Xiong et al., 2013)

Expression of Hsap\MAPT^{V337M.Scer\UAS} under the control of Scer\GAL4^GMR.PU results in smaller adult eye size and a moderate rough eye phenotype.

(Shulman et al., 2011)

Pan-neuronal expression of Hsap\MAPT^{V337M.Scer\UAS} under the control of Scer\GAL4^elav.PU results in mild mushroom body (MB) defects in approximately half of the brains examined. The deficits consist mainly of an overall reduction in the size of the MBs, but curiously, in most of the affected animals, the effect appears mostly unilateral

(Kosmidis et al., 2010)

Expression of Hsap\MAPT^{V337M.Scer\UAS} in the developing eye under the control of Scer\GAL4^GMR.PF generates a mild rough eye phenotype.

Expression of Hsap\MAPT^{V337M.Scer\UAS} in the developing external sensory organs under the control of Scer\GAL4^Eq1 generates a moderate degree of bristle loss.

(Yeh et al., 2010)

Expression of Hsap\MAPT^{V337M.Scer\UAS} using Scer\GAL4^GMR.PF produces a rough and reduced eye.

(Mallik and Lakhotia, 2009)

Expression of Hsap\MAPT^{V337M.Scer\UAS} in the eye under the control of Scer\GAL4^GMR.PF results in a rough-eye phenotype.

(Fulga et al., 2007, Khurana et al., 2006)

Expression of Hsap\MAPT^{V337M.Scer\UAS}, in the eye under the regulation of Scer\GAL4^GMR.PF results in a reduction in eye size and the loss of photoreceptor neurons.

(Yang et al., 2005)

Flies expressing Hsap\MAPT^{V337M.Scer\UAS} under the control of Scer\GAL4^GMR.PF have a rough eye phenotype. The eye is reduced in size and the regular array of lenses is disrupted. Flies expressing Hsap\MAPT^{V337M.Scer\UAS} under the control of Scer\GAL4^elav.PLu have a rough eye phenotype.

(Shulman and Feany, 2003)

No evidence of large filamentous aggregates (neurofibrillary tangles) is seen in the brains of adults expressing Hsap\MAPT^{V337M.Scer\UAS} under the control of Scer\GAL4^unspecified. The flies show neurodegeneration in the brain.

(Wittmann et al., 2001)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has visible | adult stage phenotype, enhanceable by glob1^UAS.cYa, Scer\GAL4^GMR.PU

(Nisha and Sarkar, 2021)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has decreased size | adult stage phenotype, enhanceable by glob1^UAS.cYa, Scer\GAL4^GMR.PU

(Nisha and Sarkar, 2021)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has visible | adult stage phenotype, enhanceable by sgg^UAS.cBa, Scer\GAL4^GMR.PU

(Nisha and Sarkar, 2021)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has abnormal size | adult stage phenotype, enhanceable by snRNP-U1-70K^HMS00274, Scer\GAL4^GMR.PU

(Hsieh et al., 2019)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has visible | adult stage phenotype, enhanceable by snRNP-U1-70K^HMS00274, Scer\GAL4^GMR.PU

(Hsieh et al., 2019)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has abnormal size | adult stage phenotype, enhanceable by snRNP-U1-70K^GD13212, Scer\GAL4^GMR.PU

(Hsieh et al., 2019)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has visible | adult stage phenotype, enhanceable by snRNP-U1-70K^GD13212, Scer\GAL4^GMR.PU

(Hsieh et al., 2019)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has abnormal size | adult stage phenotype, enhanceable by snRNP-U1-C^HMS00137, Scer\GAL4^GMR.PU

(Hsieh et al., 2019)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has visible | adult stage phenotype, enhanceable by snRNP-U1-C^HMS00137, Scer\GAL4^GMR.PU

(Hsieh et al., 2019)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has abnormal size | adult stage phenotype, enhanceable by snRNP-U1-C^GD11660, Scer\GAL4^GMR.PU

(Hsieh et al., 2019)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has visible | adult stage phenotype, enhanceable by snRNP-U1-C^GD11660, Scer\GAL4^GMR.PU

(Hsieh et al., 2019)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has abnormal size | adult stage phenotype, enhanceable by SmD3^HMS00361, Scer\GAL4^GMR.PU

(Hsieh et al., 2019)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has visible | adult stage phenotype, enhanceable by SmD3^HMS00361, Scer\GAL4^GMR.PU

(Hsieh et al., 2019)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has abnormal size | adult stage phenotype, enhanceable by SmD2^HMC03839, Scer\GAL4^GMR.PU

(Hsieh et al., 2019)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has visible | adult stage phenotype, enhanceable by SmD2^HMC03839, Scer\GAL4^GMR.PU

(Hsieh et al., 2019)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has abnormal size | adult stage phenotype, enhanceable by SmD2^GD7741, Scer\GAL4^GMR.PU

(Hsieh et al., 2019)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has visible | adult stage phenotype, enhanceable by SmD2^GD7741, Scer\GAL4^GMR.PU

(Hsieh et al., 2019)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has abnormal size | adult stage phenotype, enhanceable by SmE^HMS00074, Scer\GAL4^GMR.PU

(Hsieh et al., 2019)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has visible | adult stage phenotype, enhanceable by SmE^HMS00074, Scer\GAL4^GMR.PU

(Hsieh et al., 2019)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has abnormal size | adult stage phenotype, enhanceable by SmE^GD13663, Scer\GAL4^GMR.PU

(Hsieh et al., 2019)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has visible | adult stage phenotype, enhanceable by SmE^GD13663, Scer\GAL4^GMR.PU

(Hsieh et al., 2019)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has abnormal size | adult stage phenotype, enhanceable by SNRPG^GD15460, Scer\GAL4^GMR.PU

(Hsieh et al., 2019)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has visible | adult stage phenotype, enhanceable by SNRPG^GD15460, Scer\GAL4^GMR.PU

(Hsieh et al., 2019)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has abnormal size | adult stage phenotype, enhanceable by SmB^HM05097, Scer\GAL4^GMR.PU

(Hsieh et al., 2019)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has visible | adult stage phenotype, enhanceable by SmB^HM05097, Scer\GAL4^GMR.PU

(Hsieh et al., 2019)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has abnormal size | adult stage phenotype, enhanceable by SmB^KK102021, Scer\GAL4^GMR.PU

(Hsieh et al., 2019)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has visible | adult stage phenotype, enhanceable by SmB^KK102021, Scer\GAL4^GMR.PU

(Hsieh et al., 2019)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has visible | adult stage phenotype, enhanceable by Glut1^GD4552, Scer\GAL4^GMR.PU

(Shulman et al., 2011)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has visible | adult stage phenotype, enhanceable by sli^GD5822, Scer\GAL4^GMR.PU

(Shulman et al., 2011)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has visible | adult stage phenotype, enhanceable by fne^UAS.cCa, Scer\GAL4^GMR.PU

(Shulman et al., 2011)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has visible | adult stage phenotype, enhanceable by β-Spec^dsRNA.UAS, Scer\GAL4^GMR.PU

(Shulman et al., 2011)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has visible | adult stage phenotype, enhanceable by Hs6st^GD3078, Scer\GAL4^GMR.PU

(Shulman et al., 2011)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has visible | adult stage phenotype, enhanceable by dlg1^GD4689, Scer\GAL4^GMR.PU

(Shulman et al., 2011)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, enhanceable by Diap1^j5C8

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, enhanceable by CG7231^EP2510, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, enhanceable by Fem-1^EP2504, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, enhanceable by Cdk5^UAS.Tag:FLAG/Cdk5α^UAS.cMa, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, enhanceable by Atx2^EP3145, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, enhanceable by EP1072^EP1072/Orct2^EP1072, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, enhanceable by EP2190^EP2190, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, enhanceable by Fmr1^EP3517, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, enhanceable by Mmus\Prkaca^mC.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, enhanceable by Pka-C1^UAS.Tag:FLAG, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, enhanceable by aop^EP2500, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, enhanceable by cdi^EP3319, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, enhanceable by chb^EP3403, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, enhanceable by cher^EP3715, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, enhanceable by dally^EP581, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, enhanceable by EP639^EP2437, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, enhanceable by fry^EP326, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, enhanceable by garz^EP2028, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, enhanceable by hep^UAS.cBa, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, enhanceable by wdb^EP3559, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, enhanceable by Tao^EP1455, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, enhanceable by Df(2R)w73-1

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, enhanceable by Diap1^SL

(Shulman and Feany, 2003)

NOT Enhanced by

Statement

Reference

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-enhanceable by Fmr1^Δ50M

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-enhanceable by lncRNA:Hsrω^neo55

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-enhanceable by Prosβ6¹

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-enhanceable by Sc2⁰⁵⁶³⁴

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-enhanceable by Sin3A⁰⁸²⁶⁹

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-enhanceable by aop¹

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-enhanceable by cher^BG02734

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-enhanceable by dally^P16852A

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-enhanceable by par-1^W3

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-enhanceable by stg⁰¹²³⁵

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-enhanceable by twe^k08310

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-enhanceable by Cdk5α^UAS.cMa, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-enhanceable by Cdk5^UAS.Tag:FLAG, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-enhanceable by GstE1^EP2231, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-enhanceable by Hsap\HSPA1L^UAS.cWa, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-enhanceable by Hsc70-4^K71S.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-enhanceable by Nup44A^EP2417, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-enhanceable by Prosβ6^1.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-enhanceable by HDAC1^EP3672, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-enhanceable by Sin3A^EP866, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-enhanceable by Sirt1^EP2300, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-enhanceable by UbcE2H^EP1303, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-enhanceable by cpo^EP3378, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-enhanceable by eff^EP674, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-enhanceable by mub^EP3623, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-enhanceable by pum^EP3461, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-enhanceable by tara^EP3463, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Suppressed by

Statement

Reference

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has visible | adult stage phenotype, suppressible | partially by glob1^HMS01556, Scer\GAL4^GMR.PU

(Nisha and Sarkar, 2021)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has decreased size | adult stage phenotype, suppressible | partially by glob1^HMS01556, Scer\GAL4^GMR.PU

(Nisha and Sarkar, 2021)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has increased cell death | larval stage phenotype, suppressible | partially by glob1^HMS01556, Scer\GAL4^GMR.PU

(Nisha and Sarkar, 2021)

Hsap\MAPT^V337M.UAS, Scer\GAL4^elav.PLu has short lived phenotype, suppressible by glob1^HMS01556, Scer\GAL4^elav.PLu

(Nisha and Sarkar, 2021)

Hsap\MAPT^V337M.UAS, Scer\GAL4^elav.PLu has abnormal neuroanatomy | adult stage phenotype, suppressible | partially by glob1^HMS01556, Scer\GAL4^elav.PLu

(Nisha and Sarkar, 2021)

Hsap\MAPT^V337M.UAS, Scer\GAL4^elav.PLu has decreased size | adult stage phenotype, suppressible | partially by glob1^HMS01556, Scer\GAL4^elav.PLu

(Nisha and Sarkar, 2021)

Hsap\MAPT^V337M.UAS, Scer\GAL4^elav.PLu has abnormal locomotor behavior | adult stage | progressive phenotype, suppressible by glob1^HMS01556, Scer\GAL4^elav.PLu

(Nisha and Sarkar, 2021)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has visible | adult stage phenotype, suppressible | partially by sgg^KK108994, Scer\GAL4^GMR.PU

(Nisha and Sarkar, 2021)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU, sgg^KK108994 has visible | adult stage phenotype, suppressible | partially by glob1^HMS01556, Scer\GAL4^GMR.PU

(Nisha and Sarkar, 2021)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU, sgg^UAS.cBa has visible | adult stage phenotype, suppressible | partially by glob1^HMS01556, Scer\GAL4^GMR.PU

(Nisha and Sarkar, 2021)

Hsap\MAPT^V337M.UAS, Scer\GAL4^elav.PU has abnormal neuroanatomy | third instar larval stage phenotype, suppressible by αTub84B^K40Q/αTub84B^K40Q

(Mao et al., 2017)

Hsap\MAPT^V337M.UAS, Scer\GAL4^elav.PU has abnormal neuroanatomy | third instar larval stage phenotype, suppressible by αTub84B^K40R/αTub84B^K40R

(Mao et al., 2017)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has visible | adult stage phenotype, suppressible | partially by Glut1^d05758, Scer\GAL4^GMR.PU

(Shulman et al., 2011)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has visible | adult stage phenotype, suppressible | partially by sli^UAS.cBa, Scer\GAL4^GMR.PU

(Shulman et al., 2011)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has visible | adult stage phenotype, suppressible | partially by fne^KK108902, Scer\GAL4^GMR.PU

(Shulman et al., 2011)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, suppressible by fry⁰²²⁴⁰

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, suppressible by Diap1^GMR.PH

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, suppressible by Orct2^EP3569, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, suppressible by CG3735^EP2311, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, suppressible by Gbs-70E^EP3518, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, suppressible by par-1^EP899, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, suppressible by par-1^{N1S.UASp.mGFP6}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, suppressible by stg^EP1213, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, suppressible by stg^EP3426, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, suppressible by stg^EP3432, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, suppressible by stg^UAS.cNa, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, suppressible by Diap1^EP3308, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, suppressible by wun^EP2208, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, suppressible by Diap1^UAS.cLa, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, suppressible by twe^EP613, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

NOT suppressed by

Statement

Reference

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-suppressible by stg⁰¹²³⁵

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-suppressible by twe^k08310

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-suppressible by GstE1^EP2231, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-suppressible by Hsap\HSPA1L^UAS.cWa, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-suppressible by Hsc70-4^K71S.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-suppressible by Nup44A^EP2417, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-suppressible by Prosβ6^1.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-suppressible by HDAC1^EP3672, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-suppressible by Sin3A^EP866, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-suppressible by Sirt1^EP2300, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-suppressible by UbcE2H^EP1303, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-suppressible by cpo^EP3378, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-suppressible by eff^EP674, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-suppressible by mub^EP3623, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-suppressible by pum^EP3461, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-suppressible by tara^EP3463, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-suppressible by Cdk5α^UAS.cMa, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-suppressible by Fmr1^Δ50M

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-suppressible by lncRNA:Hsrω^neo55

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-suppressible by Prosβ6¹

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-suppressible by Sc2⁰⁵⁶³⁴

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-suppressible by Sin3A⁰⁸²⁶⁹

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-suppressible by aop¹

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-suppressible by Cdk5^UAS.Tag:FLAG, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-suppressible by cher^BG02734

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-suppressible by dally^P16852A

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has visible phenotype, non-suppressible by par-1^W3

(Shulman and Feany, 2003)

Phenotype Manifest In

Enhanced by

Statement

Reference

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by glob1^UAS.cYa, Scer\GAL4^GMR.PU

(Nisha and Sarkar, 2021)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has ommatidium phenotype, enhanceable by glob1^UAS.cYa, Scer\GAL4^GMR.PU

(Nisha and Sarkar, 2021)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has interommatidial bristle phenotype, enhanceable by glob1^UAS.cYa, Scer\GAL4^GMR.PU

(Nisha and Sarkar, 2021)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has rhabdomere of eye photoreceptor cell | adult stage phenotype, enhanceable by glob1^UAS.cYa, Scer\GAL4^GMR.PU

(Nisha and Sarkar, 2021)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has rhabdomere of eye photoreceptor cell | pupal stage phenotype, enhanceable by glob1^UAS.cYa, Scer\GAL4^GMR.PU

(Nisha and Sarkar, 2021)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has ommatidium | pupal stage phenotype, enhanceable by glob1^UAS.cYa, Scer\GAL4^GMR.PU

(Nisha and Sarkar, 2021)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by sgg^UAS.cBa, Scer\GAL4^GMR.PU

(Nisha and Sarkar, 2021)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by snRNP-U1-70K^HMS00274, Scer\GAL4^GMR.PU

(Hsieh et al., 2019)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by snRNP-U1-70K^GD13212, Scer\GAL4^GMR.PU

(Hsieh et al., 2019)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by snRNP-U1-C^HMS00137, Scer\GAL4^GMR.PU

(Hsieh et al., 2019)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by snRNP-U1-C^GD11660, Scer\GAL4^GMR.PU

(Hsieh et al., 2019)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by SmD3^HMS00361, Scer\GAL4^GMR.PU

(Hsieh et al., 2019)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by SmD2^HMC03839, Scer\GAL4^GMR.PU

(Hsieh et al., 2019)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by SmD2^GD7741, Scer\GAL4^GMR.PU

(Hsieh et al., 2019)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by SmE^HMS00074, Scer\GAL4^GMR.PU

(Hsieh et al., 2019)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by SmE^GD13663, Scer\GAL4^GMR.PU

(Hsieh et al., 2019)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by SNRPG^GD15460, Scer\GAL4^GMR.PU

(Hsieh et al., 2019)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by SmB^HM05097, Scer\GAL4^GMR.PU

(Hsieh et al., 2019)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by SmB^KK102021, Scer\GAL4^GMR.PU

(Hsieh et al., 2019)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has eye | adult stage phenotype, enhanceable by Glut1^GD4552, Scer\GAL4^GMR.PU

(Shulman et al., 2011)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has eye | adult stage phenotype, enhanceable by sli^GD5822, Scer\GAL4^GMR.PU

(Shulman et al., 2011)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has eye | adult stage phenotype, enhanceable by fne^UAS.cCa, Scer\GAL4^GMR.PU

(Shulman et al., 2011)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has eye | adult stage phenotype, enhanceable by β-Spec^dsRNA.UAS, Scer\GAL4^GMR.PU

(Shulman et al., 2011)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has eye | adult stage phenotype, enhanceable by Hs6st^GD3078, Scer\GAL4^GMR.PU

(Shulman et al., 2011)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has eye | adult stage phenotype, enhanceable by dlg1^GD4689, Scer\GAL4^GMR.PU

(Shulman et al., 2011)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, enhanceable by Act5C^UAS.GFP, Scer\GAL4^GMR.PF

(Fulga et al., 2007)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, enhanceable by CycD^UAS.cMa, Scer\GAL4^GMR.PF

(Khurana et al., 2006)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, enhanceable by CycB^UAS.cWa, Scer\GAL4^GMR.PF

(Khurana et al., 2006)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, enhanceable by CycA^UAS.cWa, Scer\GAL4^GMR.PF

(Khurana et al., 2006)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, enhanceable by Rheb^AV4, Scer\GAL4^GMR.PF

(Khurana et al., 2006)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, enhanceable by Atx2^EP3145, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, enhanceable by Atx2^EP3145, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, enhanceable by CG7231^EP2510, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, enhanceable by Fem-1^EP2504, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, enhanceable by Fem-1^EP2504, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, enhanceable by Cdk5^UAS.Tag:FLAG/Cdk5α^UAS.cMa, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, enhanceable by Cdk5^UAS.Tag:FLAG/Cdk5α^UAS.cMa, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, enhanceable by EP1072^EP1072/Orct2^EP1072, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, enhanceable by EP1072^EP1072/Orct2^EP1072, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, enhanceable by EP2190^EP2190, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, enhanceable by EP2190^EP2190, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, enhanceable by Fmr1^EP3517, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, enhanceable by Fmr1^EP3517, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, enhanceable by Mmus\Prkaca^mC.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, enhanceable by Mmus\Prkaca^mC.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, enhanceable by EP639^EP2437, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, enhanceable by Pka-C1^UAS.Tag:FLAG, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, enhanceable by Pka-C1^UAS.Tag:FLAG, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, enhanceable by aop^EP2500, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, enhanceable by aop^EP2500, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, enhanceable by cdi^EP3319, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, enhanceable by cdi^EP3319, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, enhanceable by chb^EP3403, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, enhanceable by EP639^EP2437, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, enhanceable by chb^EP3403, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, enhanceable by cher^EP3715, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, enhanceable by cher^EP3715, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, enhanceable by dally^EP581, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, enhanceable by dally^EP581, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, enhanceable by fry^EP326, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, enhanceable by fry^EP326, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, enhanceable by garz^EP2028, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, enhanceable by garz^EP2028, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, enhanceable by hep^UAS.cBa, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, enhanceable by hep^UAS.cBa, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, enhanceable by wdb^EP3559, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, enhanceable by wdb^EP3559, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, enhanceable by Tao^EP1455, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, enhanceable by Tao^EP1455, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, enhanceable by CG7231^EP2510, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, enhanceable by Df(2R)w73-1

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, enhanceable by Df(2R)w73-1

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, enhanceable by Diap1^SL

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, enhanceable by Diap1^SL

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, enhanceable by Diap1^j5C8

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, enhanceable by Diap1^j5C8

(Shulman and Feany, 2003)

NOT Enhanced by

Statement

Reference

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-enhanceable by lncRNA:Hsrω^EP3037, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Mallik and Lakhotia, 2009)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-enhanceable by lncRNA:Hsrω^EP93D, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Mallik and Lakhotia, 2009)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-enhanceable by Fmr1^Δ50M

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, non-enhanceable by Fmr1^Δ50M

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-enhanceable by lncRNA:Hsrω^neo55

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-enhanceable by Prosβ6¹

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-enhanceable by Sc2⁰⁵⁶³⁴

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-enhanceable by Sin3A⁰⁸²⁶⁹

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-enhanceable by aop¹

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, non-enhanceable by aop¹

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-enhanceable by cher^BG02734

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, non-enhanceable by cher^BG02734

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-enhanceable by dally^P16852A

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, non-enhanceable by dally^P16852A

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-enhanceable by par-1^W3

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, non-enhanceable by par-1^W3

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-enhanceable by stg⁰¹²³⁵

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, non-enhanceable by stg⁰¹²³⁵

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-enhanceable by twe^k08310

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, non-enhanceable by twe^k08310

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-enhanceable by Cdk5α^UAS.cMa, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-enhanceable by Cdk5^UAS.Tag:FLAG, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-enhanceable by GstE1^EP2231, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-enhanceable by Hsap\HSPA1L^UAS.cWa, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-enhanceable by Hsc70-4^K71S.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-enhanceable by Nup44A^EP2417, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-enhanceable by Prosβ6^1.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-enhanceable by HDAC1^EP3672, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-enhanceable by Sin3A^EP866, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-enhanceable by Sirt1^EP2300, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-enhanceable by UbcE2H^EP1303, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-enhanceable by cpo^EP3378, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-enhanceable by eff^EP674, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-enhanceable by mub^EP3623, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-enhanceable by pum^EP3461, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-enhanceable by tara^EP3463, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Suppressed by

Statement

Reference

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has eye phenotype, suppressible | partially by glob1^HMS01556, Scer\GAL4^GMR.PU

(Nisha and Sarkar, 2021)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has ommatidium phenotype, suppressible | partially by glob1^HMS01556, Scer\GAL4^GMR.PU

(Nisha and Sarkar, 2021)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has interommatidial bristle phenotype, suppressible | partially by glob1^HMS01556, Scer\GAL4^GMR.PU

(Nisha and Sarkar, 2021)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has rhabdomere of eye photoreceptor cell | adult stage phenotype, suppressible | partially by glob1^HMS01556, Scer\GAL4^GMR.PU

(Nisha and Sarkar, 2021)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has ommatidium | pupal stage phenotype, suppressible | partially by glob1^HMS01556, Scer\GAL4^GMR.PU

(Nisha and Sarkar, 2021)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has rhabdomere of eye photoreceptor cell | pupal stage phenotype, suppressible | partially by glob1^HMS01556, Scer\GAL4^GMR.PU

(Nisha and Sarkar, 2021)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has eye disc phenotype, suppressible | partially by glob1^HMS01556, Scer\GAL4^GMR.PU

(Nisha and Sarkar, 2021)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has mitochondrion | larval stage phenotype, suppressible | partially by glob1^HMS01556, Scer\GAL4^GMR.PU

(Nisha and Sarkar, 2021)

Hsap\MAPT^V337M.UAS, Scer\GAL4^elav.PLu has adult brain phenotype, suppressible | partially by glob1^HMS01556, Scer\GAL4^elav.PLu

(Nisha and Sarkar, 2021)

Hsap\MAPT^V337M.UAS, Scer\GAL4^elav.PLu has axon | adult stage phenotype, suppressible by glob1^HMS01556, Scer\GAL4^elav.PLu

(Nisha and Sarkar, 2021)

Hsap\MAPT^V337M.UAS, Scer\GAL4^elav.PLu has adult Kenyon cell phenotype, suppressible by glob1^HMS01556, Scer\GAL4^elav.PLu

(Nisha and Sarkar, 2021)

Hsap\MAPT^V337M.UAS, Scer\GAL4^elav.PLu has lobe system of adult mushroom body phenotype, suppressible by glob1^HMS01556, Scer\GAL4^elav.PLu

(Nisha and Sarkar, 2021)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has eye phenotype, suppressible | partially by sgg^KK108994, Scer\GAL4^GMR.PU

(Nisha and Sarkar, 2021)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU, sgg^KK108994 has eye phenotype, suppressible | partially by glob1^HMS01556, Scer\GAL4^GMR.PU

(Nisha and Sarkar, 2021)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU, sgg^UAS.cBa has eye phenotype, suppressible | partially by glob1^HMS01556, Scer\GAL4^GMR.PU

(Nisha and Sarkar, 2021)

Hsap\MAPT^V337M.UAS, Scer\GAL4^C57 has embryonic/larval somatic muscle cell | third instar larval stage phenotype, suppressible by αTub84B^K40Q/αTub84B^K40Q

(Mao et al., 2017)

Hsap\MAPT^V337M.UAS, Scer\GAL4^C57 has cytoplasmic microtubule | third instar larval stage phenotype, suppressible by αTub84B^K40Q/αTub84B^K40Q

(Mao et al., 2017)

Hsap\MAPT^V337M.UAS, Scer\GAL4^elav.PU has NMJ bouton | increased number | third instar larval stage phenotype, suppressible by αTub84B^K40Q/αTub84B^K40Q

(Mao et al., 2017)

Hsap\MAPT^V337M.UAS, Scer\GAL4^C57 has embryonic/larval somatic muscle cell | third instar larval stage phenotype, suppressible | partially by αTub84B^K40R/αTub84B^K40R

(Mao et al., 2017)

Hsap\MAPT^V337M.UAS, Scer\GAL4^C57 has cytoplasmic microtubule | third instar larval stage phenotype, suppressible | partially by αTub84B^K40R/αTub84B^K40R

(Mao et al., 2017)

Hsap\MAPT^V337M.UAS, Scer\GAL4^elav.PU has NMJ bouton | increased number | third instar larval stage phenotype, suppressible by αTub84B^K40R/αTub84B^K40R

(Mao et al., 2017)

Hsap\MAPT^V337M.UAS, Scer\GAL4^C57 has microtubule phenotype, suppressible by HDAC6^KO

(Xiong et al., 2013)

Hsap\MAPT^V337M.UAS, Scer\GAL4^C57 has microtubule phenotype, suppressible by Df(1)ED7294/HDAC6^KO

(Xiong et al., 2013)

Hsap\MAPT^V337M.UAS, Scer\GAL4^elav.PU has embryonic/larval neuromuscular junction | larval stage phenotype, suppressible by HDAC6^KO

(Xiong et al., 2013)

Hsap\MAPT^V337M.UAS, Scer\GAL4^elav.PU has NMJ bouton | larval stage phenotype, suppressible by HDAC6^KO

(Xiong et al., 2013)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has eye | adult stage phenotype, suppressible | partially by Glut1^d05758, Scer\GAL4^GMR.PU

(Shulman et al., 2011)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has eye | adult stage phenotype, suppressible | partially by sli^UAS.cBa, Scer\GAL4^GMR.PU

(Shulman et al., 2011)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PU has eye | adult stage phenotype, suppressible | partially by fne^KK108902, Scer\GAL4^GMR.PU

(Shulman et al., 2011)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, suppressible | partially by Hsrω^{a.Sym.Scer\UAS}/lncRNA:Hsrω^{dsRNA.Sym.UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Mallik and Lakhotia, 2009)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, suppressible by tsr^{UAS.Tag:polyHis}, Scer\GAL4^GMR.PF

(Fulga et al., 2007)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, suppressible by Act5C^G0010/Act5C[+]

(Fulga et al., 2007)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, suppressible by dap^UAS.cdNa/Rbf^UAS.cDa, Scer\GAL4^GMR.PF

(Khurana et al., 2006)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, suppressible by E2f[+]/E2f1⁹¹

(Khurana et al., 2006)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, suppressible by CycA^C8LR1/CycA[+]

(Khurana et al., 2006)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, suppressible by dap^UAS.cdNa/Cdk1^E51Q.UAS, Scer\GAL4^GMR.PF

(Khurana et al., 2006)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, suppressible by S6k⁰⁷⁰⁸⁴/S6k^l-1

(Khurana et al., 2006)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, suppressible by Tor^2L15/Tor^2L7

(Khurana et al., 2006)

Hsap\MAPT^V337M.UAS, Rheb^AV4, Scer\GAL4^GMR.PF has eye phenotype, suppressible by Cdk4³/Cdk4[+]

(Khurana et al., 2006)

Hsap\MAPT^V337M.UAS, Rheb^AV4, Scer\GAL4^GMR.PF has eye phenotype, suppressible by dap^UAS.cdNa/Rbf^UAS.cDa, Scer\GAL4^GMR.PF

(Khurana et al., 2006)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, suppressible by fry⁰²²⁴⁰

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, suppressible by fry⁰²²⁴⁰

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, suppressible by Diap1^GMR.PH

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, suppressible by Diap1^GMR.PH

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, suppressible by Orct2^EP3569, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, suppressible by Orct2^EP3569, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, suppressible by CG3735^EP2311, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, suppressible by CG3735^EP2311, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, suppressible by Gbs-70E^EP3518, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, suppressible by Gbs-70E^EP3518, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, suppressible by par-1^EP899, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, suppressible by par-1^EP899, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, suppressible by par-1^{N1S.UASp.mGFP6}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, suppressible by par-1^{N1S.UASp.mGFP6}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, suppressible by stg^EP1213, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, suppressible by stg^EP1213, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, suppressible by stg^EP3426, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, suppressible by stg^EP3426, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, suppressible by stg^EP3432, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, suppressible by stg^EP3432, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, suppressible by stg^UAS.cNa, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, suppressible by stg^UAS.cNa, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, suppressible by Diap1^EP3308, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, suppressible by Diap1^EP3308, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, suppressible by wun^EP2208, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, suppressible by wun^EP2208, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, suppressible by Diap1^UAS.cLa, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, suppressible by twe^EP613, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

NOT suppressed by

Statement

Reference

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-suppressible by Pi3K92E^UAS.Tag:MYC, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Yang et al., 2005)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye photoreceptor cell phenotype, non-suppressible by Pi3K92E^UAS.Tag:MYC, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Yang et al., 2005)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye photoreceptor cell phenotype, non-suppressible by Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Yang et al., 2005)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-suppressible by Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Yang et al., 2005)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye photoreceptor cell phenotype, non-suppressible by Pten^UAS.cHa, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Yang et al., 2005)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-suppressible by Pten^UAS.cHa, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Yang et al., 2005)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-suppressible by GstE1^EP2231, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-suppressible by twe^k08310

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, non-suppressible by twe^k08310

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-suppressible by Hsap\HSPA1L^UAS.cWa, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-suppressible by Hsc70-4^K71S.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-suppressible by Nup44A^EP2417, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-suppressible by Prosβ6^1.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-suppressible by HDAC1^EP3672, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-suppressible by Sin3A^EP866, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-suppressible by Sirt1^EP2300, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-suppressible by UbcE2H^EP1303, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-suppressible by cpo^EP3378, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-suppressible by eff^EP674, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-suppressible by mub^EP3623, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-suppressible by pum^EP3461, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-suppressible by tara^EP3463, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, non-suppressible by Cdk5α^UAS.cMa, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-suppressible by Fmr1^Δ50M

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, non-suppressible by Fmr1^Δ50M

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-suppressible by lncRNA:Hsrω^neo55

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, non-suppressible by Cdk5^UAS.Tag:FLAG, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-suppressible by Prosβ6¹

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-suppressible by Sc2⁰⁵⁶³⁴

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-suppressible by Sin3A⁰⁸²⁶⁹

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-suppressible by aop¹

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, non-suppressible by aop¹

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-suppressible by cher^BG02734

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, non-suppressible by cher^BG02734

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-suppressible by dally^P16852A

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, non-suppressible by dally^P16852A

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-suppressible by par-1^W3

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, non-suppressible by par-1^W3

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has eye phenotype, non-suppressible by stg⁰¹²³⁵

(Shulman and Feany, 2003)

Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF has ommatidium phenotype, non-suppressible by stg⁰¹²³⁵

(Shulman and Feany, 2003)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

The decreased density of perinuclear microtubules (MTs) in larval muscle cells characteristic for third instar larvae expressing Hsap\MAPT^{V337M.Scer\UAS} (with the Scer\GAL4^C57 driver) as well as the excess of satellite boutons at larval neuromuscular junctions (with the Scer\GAL4^elav.PU driver) is fully suppressed by αTub84B^K40Q homozygosity. Unexpectedly, the microtubule as well as the neuromuscular junction phenotype of Hsap\MAPT^{V337M.Scer\UAS}-expressing larvae can be partially or fully rescued (respectively) by αTub84B^K40R homozygosity too.

(Mao et al., 2017)

HDAC6^KO and HDAC6^KO/Df(1)ED7294 each rescue the defects in perinuclear microtubule density seen in the muscles of animals expressing Hsap\MAPT^{V337M.Scer\UAS} under the control of Scer\GAL4^C57.

HDAC6^KO completely suppresses the increase in the number of satellite boutons at the neuromuscular junction (NMJ) and the decrease in average NMJ length caused by expression of Hsap\MAPT^{V337M.Scer\UAS} under the control of Scer\GAL4^elav.PU.

(Xiong et al., 2013)

The moderate rough eye phenotype and reduced adult eye size characteristic for flies expressing Scer\GAL4^GMR.PU under the control of Hsap\MAPT^{V337M.Scer\UAS} is suppressed by co-expression of any of: Glut1^d05758, sli^Scer\UAS.cBa or fne^KK108902, restoring a near wild-type phenotype, and significantly worsened by co-expression of any of the following: Glut1^GD4552 , sli^GD5822, β-Spec^{dsRNA.Scer\UAS}, Hs6st^GD3078, dlg1^GD4689 (each expressed together with UAS-Dicer2 to enhance RNAi efficiency) or fne^Scer\UAS.cCa, exacerbating the rough appearance.

(Shulman et al., 2011)

Expression of Act5C^{Scer\UAS.T:Avic\GFP} in flies expressing Hsap\MAPT^{V337M.Scer\UAS} in the eye under the control of Scer\GAL4^GMR.PF enhances the rough-eye phenotype.

Expression of tsr^{Scer\UAS.T:Zzzz\His6} in flies expressing Hsap\MAPT^{V337M.Scer\UAS} in the eye under the control of Scer\GAL4^GMR.PF suppresses the rough-eye phenotype.

The rough-eye phenotype observed in flies expressing Hsap\MAPT^{V337M.Scer\UAS} in the eye under the control of Scer\GAL4^GMR.PF is suppressed in a Act5C^G0010/+ background.

(Fulga et al., 2007)

The rough-eye phenotype observed in animals expressing Hsap\MAPT^{V337M.Scer\UAS} under the control of Scer\GAL4^GMR.PF is suppressed by co-expression of dap^{Scer\UAS.cdNa} and Rbf^Scer\UAS.cDa.

The rough-eye phenotype observed in animals expressing Hsap\MAPT^{V337M.Scer\UAS} under the control of Scer\GAL4^GMR.PF is suppressed in a E2f⁹¹/+ background.

The rough-eye phenotype observed in animals expressing Hsap\MAPT^{V337M.Scer\UAS} under the control of Scer\GAL4^GMR.PF is suppressed in a CycA^C8LR1/+ background.

The rough-eye phenotype observed in animals expressing Hsap\MAPT^{V337M.Scer\UAS} under the control of Scer\GAL4^GMR.PF is suppressed by co-expression of dap^{Scer\UAS.cdNa} and cdc2^{E51Q.Scer\UAS}.

The rough-eye phenotype observed in animals expressing Hsap\MAPT^{V337M.Scer\UAS} under the control of Scer\GAL4^GMR.PF is enhanced by co-expression of CycD^Scer\UAS.cMa.

The rough-eye phenotype observed in animals expressing Hsap\MAPT^{V337M.Scer\UAS} under the control of Scer\GAL4^GMR.PF is enhanced by co-expression of CycB^Scer\UAS.cWa.

The rough-eye phenotype observed in animals expressing Hsap\MAPT^{V337M.Scer\UAS} under the control of Scer\GAL4^GMR.PF is enhanced by co-expression of CycA^Scer\UAS.cWa.

The rough-eye phenotype observed in animals expressing Hsap\MAPT^{V337M.Scer\UAS} under the control of Scer\GAL4^GMR.PF is suppressed in a S6k⁰⁷⁰⁸⁴/S6k^l-1 background.

The rough eye phenotype and increased cell death observed in animals expressing Hsap\MAPT^{V337M.Scer\UAS} under the control of Scer\GAL4^GMR.PF is suppressed in a Tor^2L7/Tor^2L15 background.

The rough-eye phenotype observed in animals expressing Hsap\MAPT^{V337M.Scer\UAS} under the control of Scer\GAL4^GMR.PF is enhanced by co-expression of Rheb^AV4. This enhancement is blocked in a Cdk4³/+ background, or by co-expressing dap^{Scer\UAS.cdNa} and Rbf^Scer\UAS.cDa.

(Khurana et al., 2006)

Coexpression of Pi3K92E^{Scer\UAS.T:Hsap\MYC} with Hsap\MAPT^{V337M.Scer\UAS}, under the control of Scer\GAL4^GMR.PF has no effect on the Hsap\MAPT^{V337M.Scer\UAS}-induced toxicity in the eye. Coexpression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} with Hsap\MAPT^{V337M.Scer\UAS}, under the control of Scer\GAL4^GMR.PF has no effect on the Hsap\MAPT^{V337M.Scer\UAS}-induced toxicity in the eye. Coexpression of Pten^Scer\UAS.cHa with Hsap\MAPT^{V337M.Scer\UAS}, under the control of Scer\GAL4^GMR.PF has no effect on the Hsap\MAPT^{V337M.Scer\UAS}-induced toxicity in the eye.