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General Information
Symbol
Dmel\da::twiUAS.cCa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Castanon
FlyBase ID
FBal0127237
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

A copy of the twi coding region is separated from a copy of the da coding region by a 16 amino acid flexible polypeptide linker (G(SGGG)3SGG). This fusion protein is driven by UASt sequences.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

In embryos expressing da::twiScer\UAS.cCa under the control of Scer\GAL4twi.PG the salivary glands often fail to invaginate. In approximately half of embryos of this genotype, one gland does invaginate into the embryo, but fails to progress past the turning point to migrate posteriorly.

When da::twiScer\UAS.cCa is driven by Scer\GAL4twi.PB in the mesoderm, the somatic musculature is greatly reduced, with the remaining muscles showing defects in patterning and size. Other mesodermal tissues, such as visceral muscle are initially unaffected, though mild defects in the later development of these tissues are found.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
da::twiScer\UAS.cCa
da::twiUAS.cCa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Castanon
Secondary FlyBase IDs
    References (2)