Open Close
General Information
Symbol
Dmel\PoxmUAS.cJa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Jiao
FlyBase ID
FBal0127289
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-Poxm
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of the 2.6kb Poxm P29c1 cDNA.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of PoxmScer\UAS.cJa under the control of Scer\GAL4how-24B results in a severely altered muscle pattern in the embryo, which varies among different segments and embryos. The most striking defects are seen in the dorsal and dorsolateral muscles. Ectopic muscles are generated in most segments in the dorsal region. Ectopic muscles similar in shape and orientation to muscle DA3 are found in the dorsolateral region, which is largely free of muscles in wild-type embryos. Several muscles of abnormal shape are generally seen at the position where muscle DA1 is normally found. Muscles LL1, DO4 and DO5 have aberrant shapes or are missing in some segments. Some of the lateral muscles are abnormally shaped. The ventral muscles remain largely unaffected, although some muscle fibres appear enlarged.

Expression of PoxmScer\UAS.cJa under the control of Scer\GAL4how-24B affects the number of adult muscle precursors in stage 14 embryos; in the lateral mesoderm, in most segments the dorsolateral DLaPs are missing and only one of the two lateral LaPs is present. In the dorsal region, two dorsal DaPs instead of one are present in approximately half of the segments. In the ventral region, the number of ventral VaPs is unaffected.

Pharate adults expressing PoxmScer\UAS.cJa under the control of Scer\GAL4ey.PH show a headless phenotype. Three classes of phenotype are seen; class I pharate adults lack all head structures derived from the eye-antennal discs, class II consists of eyeless flies which lack most head structures and both antennae and class III consists of eyeless animals with large parts of the head missing but one or both antennae present.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Phenotype Manifest In
Suppressed by
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
Pox-mScer\UAS.cJa
PoxmScer\UAS.cJa
PoxmUAS.cJa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Jiao
Secondary FlyBase IDs
    References (2)