|Name||Saccharomyces cerevisiae UAS construct a of Jiao||FlyBase ID||FBal0127289|
|Feature type||allele||Associated gene||Dmel\Poxm|
|Mutagen||in vitro construct - regulatory fusion|
What does this section display?
This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).
What does this section not display?
This section does not currently display links that were removed or gene model changes.
Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
|All updates||Click here to see a list of all updates to this record from FB2010_08 and on.|
|Nature of the Allele|
|Mutations Mapped to the Genome|
|Associated Sequence Data|
|Nature of the lesion|
|Carried in construct|
|Phenotype Manifest In|
Expression of Poxm[Scer\UAS.cJa] under the control of Scer\GAL4[how-24B] results in a severely altered muscle pattern in the embryo, which varies among different segments and embryos. The most striking defects are seen in the dorsal and dorsolateral muscles. Ectopic muscles are generated in most segments in the dorsal region. Ectopic muscles similar in shape and orientation to muscle DA3 are found in the dorsolateral region, which is largely free of muscles in wild-type embryos. Several muscles of abnormal shape are generally seen at the position where muscle DA1 is normally found. Muscles LL1, DO4 and DO5 have aberrant shapes or are missing in some segments. Some of the lateral muscles are abnormally shaped. The ventral muscles remain largely unaffected, although some muscle fibres appear enlarged. Expression of Poxm[Scer\UAS.cJa] under the control of Scer\GAL4[how-24B] affects the number of adult muscle precursors in stage 14 embryos; in the lateral mesoderm, in most segments the dorsolateral DLaPs are missing and only one of the two lateral LaPs is present. In the dorsal region, two dorsal DaPs instead of one are present in approximately half of the segments. In the ventral region, the number of ventral VaPs is unaffected.
Pharate adults expressing PoxmScer\UAS.cJa under the control of Scer\GAL4ey.PH show a headless phenotype. Three classes of phenotype are seen; class I pharate adults lack all head structures derived from the eye-antennal discs, class II consists of eyeless flies which lack most head structures and both antennae and class III consists of eyeless animals with large parts of the head missing but one or both antennae present.
PoxmScer\UAS.cJa, Scer\GAL4ey.PH has visible phenotype, suppressible | partially by dmScer\UAS.cZa, Scer\GAL4ey.PH
|Phenotype Manifest In|
PoxmScer\UAS.cJa, Scer\GAL4ey.PH has adult head phenotype, suppressible | partially by dmScer\UAS.cZa, Scer\GAL4ey.PH
|Complementation & Rescue Data|
|Stocks ( 0 )|
|Notes on Origin|
|External Crossreferences & Linkouts|
|Synonyms & Secondary IDs ( 3 )|
Saccharomyces cerevisiae UAS construct a of Jiao
|Secondary FlyBase IDs|
|References ( 2 )|