Allele Dmel\phl^Δ445.hs

General Information
Symbol	Dmel\phl^Δ445.hs	Species	D. melanogaster
Name		FlyBase ID	FBal0127913
Feature type	allele	Associated gene	Dmel\phl

Allele class
Mutagen	in vitro construct - regulatory fusion, in vitro construct - deletion
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct - deletion (Radke et al., 2001) in vitro construct - regulatory fusion (Radke et al., 2001)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Construct: An Hsp70 promoter drives expression of a mutant form of phl that lacks amino acid residues 1 to 445. (Radke et al., 2001)
Carried in construct	P{hs-phl.Δ445} (Radke et al., 2001)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In

Detailed Description
	Statement Reference
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Partially rescues	phl^Δ445.hs partially rescues phl¹¹ (Radke et al., 2001)
Comments	Expression of phl^Δ445.hs in phl¹¹/Y embryos which lack both maternal and zygotic phl function rescues 52% of the embryos so that they resemble embryos which lack maternal but not zygotic phl function (having a "torso" phenotype). 18% of embryos have a composite "imperfect torso phenotype", having denticle belts of reduced width and being twisted, in addition to having the head and tail defects associated with the torso phenotype. 30% of embryos are twisted and have faint cuticles with narrow denticle belts. (Radke et al., 2001)
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	D-raf^Δ445 (Radke et al., 2001) phl^Δ445.hs
Name Synonym
Secondary FlyBase IDs

References ( 1 )
Research paper	Radke et al., 2001, Genetics 159(3): 1031--1044 Drosophila-raf acts to elaborate dorsoventral pattern in the ectoderm of developing embryos. [FBrf0141545]

Allele Dmel\phlΔ445.hs

Allele Dmel\phl^Δ445.hs