Contains an 11bp deletion, predicted to cause a truncation of the expressed product at R83 near the N terminus of the head domain, causing a frameshift closely followed by a stop codon.
11bp deletion in the myosin head domain, resulting in a frameshift and stop codon.
dGC13 partially suppresses the polarity phenotype of ft8. This is evidenced by comparison of ft8 and dGC13 single mutant clones with ft8, dGC13 double mutant clones in the abdomen. While all (39/39) ft8 clones have a polarity phenotype, only 54% of ft8, dGC13 clones show this phenotype (vs 3% of dGC13 clones). The ft8 single mutant clones exhibit some hairs at an angle greater than 90o relative to the normal orientation, while only 26% of ft8, dGC13 clones had hairs of this angle.
The polarity phenotype of ft8, dGC13 double mutant clones in the eye is similar to that of ft8 single mutant clones (28 vs 32 out of 33 clones including ommatidia rotated more than 90o away from the normal position, respectively.
Expression of either dScer\UAS.T:SV5\V5,T:Zzzz\His6 or dΔN.Scer\UAS.T:SV5\V5 under the control of Scer\GAL4tub.PU restores the viability of dGC13 mutant flies, while expresion of any of the following: dΔMH.Scer\UAS.T:SV5\V5, dΔ1C.Scer\UAS.T:SV5\V5, dΔ2C.Scer\UAS.T:SV5\V5, or dΔ3C.Scer\UAS.T:SV5\V5 does not rescue dGC13 viability.