FlyBase Allele Report: Scer\GAL4[elav.Switch.PO]

General Information

Symbol

Scer\GAL4^{elav.Switch.PO}

Species

S. cerevisiae

Name

FlyBase ID

FBal0128065

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

Carried in Construct

P{elav-Switch.O}

Also Known As

Elav-GeneSwitch, elav-GS, ElavGS, Elav-GS-GAL4, ELAV-GeneSwitch-Gal4, GS-elav, ElavGS-Gal4, GS-elav-Gal4, GSelav, elav-Switch

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

in vitro construct - regulatory fusion

(Osterwalder et al., 2001, Osterwalder et al., 2001)

in vitro construct - coding region fusion

(Osterwalder et al., 2001, Osterwalder et al., 2001)

Mutations Mapped to the Genome

Type

Location

Additional Notes

References

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Progenitor genotype

Carried in construct

P{elav-Switch.O}

Cytology

Nature of the lesion

Statement

Reference

A 3.5kb fragment of the elav gene (including the elav promoter and the 5' UTR exons 0 and 1) drives expression of the ligand-inducible GAL4::GS driver.

(Osterwalder et al., 2001)

Allele components

Product class / Tool use(s)

Regulatory region(s)

elav

Encoded product / tool

GAL4::GS

binary expression system - small molecule-regulated driver

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

larval stage

neuron

(Osterwalder et al., 2001)

adult stage

neuron

(Rana et al., 2013, Hwangbo et al., 2004)

Additional Information

Statement

Reference

Drives mifepristone-inducible expression pan-neuronally at larval and adult stages.

(FlyBase Curators, 2017)

Scer\GAL4^{elav.Switch.PO} drives mifepristone-inducible expression pan-neuronally

(Rana et al., 2013)

Expression is driven pan-neuronally.

(Hwangbo et al., 2004)

Marker for

neuron

(Hwangbo et al., 2004, Osterwalder et al., 2001)

Reflects expression of

elav

(Rana et al., 2013, Hwangbo et al., 2004, Osterwalder et al., 2001, Osterwalder et al., 2001)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Phenotypic Data

Phenotypic Class

behavior defective | RU486 conditional, with Mmus\Prkaca^mC.UAS

(Joiner et al., 2006)

behavior defective | RU486 conditional, with Pka-R1^BDK.UAS

(Wu et al., 2009)

cell cycle defective | larval stage, with tll^UAS.cKa

(Kurusu et al., 2009)

cell cycle defective | pupal stage, with tll^UAS.cKa

(Kurusu et al., 2009)

chemical resistant | RU486 conditional, with hep^UAS.cBa

(Wang et al., 2003)

chemical resistant | RU486 conditional, with p53^259H.GUS

(Bauer et al., 2005)

chemical resistant | RU486 conditional, with p53^Ct.GUS

(Bauer et al., 2005)

chemical sensitive | adult stage | RU486 conditional, with mir-310^UAS.pLUC

(Ghezzi et al., 2016)

circadian rhythm defective | RU486 conditional, with nur^{UAS.Tag:FLAG,Tag:HA}

(Toda et al., 2019)

courtship behavior defective | RU486 conditional, with EcR^{dsRNA.UAS.cIa}

(Ishimoto et al., 2009)

decreased cell number | adult stage | progressive | RU486 conditional, with Hsap\MAPT^{K280Q.UAS.2N4R}

(Gorsky et al., 2016)

decreased cell number | adult stage | progressive | RU486 conditional, with Hsap\MAPT^{K280R.UAS.2N4R}

(Gorsky et al., 2016)

decreased cell number | adult stage | progressive | RU486 conditional, with Hsap\MAPT^UAS.2N4R.wt

(Gorsky et al., 2016)

feeding behavior defective | adult stage | RU486 conditional, with fit^UAS.Tag:HA

(Sun et al., 2017)

feeding behavior defective | larval stage | RU486 conditional, with 5-HT2A^JF02157

(Gasque et al., 2013)

hyperactive | RU486 conditional, with Sh^{DN.EKI.UAS.GFP(GL)}

(Mosca et al., 2005)

immune response defective | adult stage | RU486 conditional, with nur^{UAS.Tag:FLAG,Tag:HA}

(Toda et al., 2019)

increased cell death, with rpr^UAS.C

(Khurana et al., 2006)

increased fecundity | female | RU486 conditional, with Gadd45^UASp.cPa

(Plyusnina et al., 2011)

learning defective | adult stage | adult stage | RU486 conditional, with Nrx-1^JF02652

(Dong et al., 2016)

learning defective | adult stage | adult stage | RU486 conditional, with Tsc1^JF01262

(Dong et al., 2016)

learning defective | adult stage | adult stage | RU486 conditional, with Ube3a^JF03406

(Dong et al., 2016)

learning defective | larval stage | RU486 conditional, with Egfr^DN.UAS.cBa

(Rahn et al., 2013)

learning defective | larval stage | RU486 conditional, with spi^s.UAS.EGFP

(Rahn et al., 2013)

learning defective | RU486 conditional, with sra^UAS.Tag:HA

(Chang et al., 2003)

learning defective | third instar larval stage | RU486 conditional, with Krn^KK107190

(Rahn et al., 2013)

learning defective | third instar larval stage | RU486 conditional, with spi^KK105786

(Rahn et al., 2013)

learning defective | third instar larval stage | RU486 conditional, with vn^KK108432

(Rahn et al., 2013)

lethal | RU486 conditional, with Ctet\tetX^TNT-LC.UAS

(Osterwalder et al., 2001)

lethal | RU486 conditional, with Hsap\UCP3^UAS.cHa

(Humphrey et al., 2009)

lethal - all die before end of embryonic stage, with Hsap\TARDBP^{M.UAS.Tag:FLAG}

(Miguel et al., 2011)

lethal - all die before end of embryonic stage, with Hsap\TARDBP^mutNES.UAS

(Miguel et al., 2011)

lethal - all die before end of embryonic stage, with Hsap\TARDBP^mutNLS.UAS

(Miguel et al., 2011)

lethal - all die before end of pupal stage | RU486 conditional, with ewg^UAS.cHa

(Haussmann et al., 2008)

locomotor behavior defective | adult stage, with Hsap\APP^{Arctic.UAS.Tag:SS(nec)}

(Piper et al., 2014, Sofola-Adesakin et al., 2014)

locomotor behavior defective | adult stage, with Hsap\ATXN3^70Q.UAS

(Sowa et al., 2018)

locomotor behavior defective | adult stage, with Zzzz\UGGAA^S.UAS

(Ishiguro et al., 2017)

locomotor behavior defective | adult stage | progressive | RU486 conditional, with Hsap\APP^{Arctic.UAS.Tag:SS(nec)}

(Sofola et al., 2010)

locomotor behavior defective | adult stage | progressive | RU486 conditional, with Hsap\ATXN3^70Q.UAS

(Reinhardt et al., 2012)

locomotor behavior defective | adult stage | progressive | RU486 conditional, with Hsap\MAPT^{K280Q.UAS.2N4R}

(Gorsky et al., 2016)

locomotor behavior defective | adult stage | progressive | RU486 conditional, with Hsap\MAPT^{K280R.UAS.2N4R}

(Gorsky et al., 2016)

locomotor behavior defective | adult stage | progressive | RU486 conditional, with Hsap\MAPT^UAS.2N4R.wt

(Gorsky et al., 2016)

locomotor behavior defective | adult stage | RU486 conditional, with Atg17^HMS01611

(Kim et al., 2013)

locomotor behavior defective | adult stage | RU486 conditional, with for^P1.UAS

(Kanao et al., 2012)

locomotor behavior defective | adult stage | RU486 conditional, with Hsap\APP^{Aβ40.UAS.Tag:SS(nec).cBa}, Hsap\APP^{Aβ42.UAS.Tag:SS(nec).cBa}

(Burnouf et al., 2015)

locomotor behavior defective | adult stage | RU486 conditional, with Hsap\APP^{Aβ40.UAS.Tag:SS(nec).cBa}, Hsap\APP^{Aβ43.UAS.Tag:SS(nec).cBa}

(Burnouf et al., 2015)

locomotor behavior defective | adult stage | RU486 conditional, with Hsap\APP^{Aβ42.UAS.Tag:SS(nec).cBa}

(Burnouf et al., 2015)

locomotor behavior defective | adult stage | RU486 conditional, with Hsap\APP^{Aβ42.UAS.Tag:SS(nec).cBa}, Hsap\APP^{Aβ43.UAS.Tag:SS(nec).cBa}

(Burnouf et al., 2015)

locomotor behavior defective | adult stage | RU486 conditional, with Hsap\APP^{Aβ43.UAS.Tag:SS(nec).cBa}

(Burnouf et al., 2015)

locomotor behavior defective | adult stage | RU486 conditional, with Hsap\ATXN7^{102Q.T.UAS.Tag:NLS(SV40-largeT)}

(Latouche et al., 2007)

locomotor behavior defective | adult stage | RU486 conditional, with Hsap\TARDBP^UAS.cEa

(Kim et al., 2014)

locomotor behavior defective | adult stage | RU486 conditional, with Mgat1^{dsRNA.h-h.UAS}

(Sarkar et al., 2010)

locomotor behavior defective | adult stage | RU486 conditional, with Mgat1^{dsRNA.t-t.UAS}

(Sarkar et al., 2010)

locomotor behavior defective | female limited, with park^UAS.cGa

(Rana et al., 2013)

locomotor behavior defective | RU486 conditional, with Hsap\APP^{Arctic.UAS.Tag:SS(nec)}

(Rogers et al., 2012)

locomotor behavior defective | RU486 conditional, with Hsap\FUS^{R521C.UAS.Tag:HA}

(Lanson et al., 2011)

locomotor behavior defective | RU486 conditional, with Hsap\FUS^UAS.Tag:HA

(Lanson et al., 2011)

locomotor behavior defective | RU486 conditional, with nur^{UAS.Tag:FLAG,Tag:HA}

(Toda et al., 2019)

locomotor rhythm defective, with cyc^DN.UAS

(Xu et al., 2008)

locomotor rhythm defective | RU486 conditional, with Gadd45^UASp.cPa

(Plyusnina et al., 2011)

locomotor rhythm defective | RU486 conditional, with hop^Tum.UAS

(Luo and Sehgal, 2012)

locomotor rhythm defective | RU486 conditional, with mir-279^UAS.L

(Luo and Sehgal, 2012)

locomotor rhythm defective | RU486 conditional, with mir-279^UAS.S

(Luo and Sehgal, 2012)

locomotor rhythm defective | RU486 conditional, with upd1^UAS.cUa

(Luo and Sehgal, 2012)

long lived, with RpIIIC160^GD4257

(Filer et al., 2017)

long lived | :conditional | RU486 conditional, with nur^{UAS.Tag:FLAG,Tag:HA}

(Toda et al., 2019)

long lived | female | RU486 conditional, with CG18809^GD9655

(Copeland et al., 2009)

long lived | female | RU486 conditional, with mir-let7^UAS.cCa

(Gendron and Pletcher, 2017)

long lived | female | RU486 conditional, with ND-20^GD13310

(Copeland et al., 2009)

long lived | female | RU486 conditional, with ND-SGDH^GD3876

(Copeland et al., 2009)

long lived | female limited, with park^UAS.cGa

(Rana et al., 2013)

long lived | RU486 conditional, with AhcyL1^HM05009

(Parkhitko et al., 2016)

long lived | RU486 conditional, with Atg1^UAS.cSa

(Ling and Salvaterra, 2011)

long lived | RU486 conditional, with Eip71CD^UAS.cCa

(Chung et al., 2010)

long lived | RU486 conditional, with Gadd45^UASp.cPa

(Plyusnina et al., 2011)

long lived | RU486 conditional, with Hsap\UCP2^UAS.cFa

(Fridell et al., 2005)

long lived | RU486 conditional, with Hsap\UCP3^UAS.cHa

(Humphrey et al., 2009)

long lived | RU486 conditional, with Mgat1^UAS.cSa

(Sarkar et al., 2010)

long lived | RU486 conditional, with p53^259H.GUS

(Bauer et al., 2005)

long lived | RU486 conditional, with p53^Ct.GUS

(Bauer et al., 2005)

long lived | RU486 conditional, with Scer\NDI1^UAS.cBa

(Bahadorani et al., 2010)

long lived | RU486 conditional, with Sirt1^EP2300

(Rogina and Helfand, 2004)

long lived | RU486 conditional, with teq^GD4757

(Huang et al., 2015)

memory defective, with hiw^ΔRING.UAS

(Huang et al., 2012)

memory defective | adult stage | RU486 conditional, with klg^GD14314

(Matsuno et al., 2015)

memory defective | adult stage | RU486 conditional, with Nrx-1^JF02652

(Dong et al., 2016)

memory defective | adult stage | RU486 conditional, with Tsc1^JF01262

(Dong et al., 2016)

memory defective | adult stage | RU486 conditional, with Ube3a^JF03406

(Dong et al., 2016)

memory defective | RU486 conditional, with EcR^{dsRNA.UAS.cIa}

(Ishimoto et al., 2009)

memory defective | RU486 conditional, with Nmdar1^N631Q.UAS

(Miyashita et al., 2012)

neuroanatomy defective, with hiw^UAS.Tag:TAP

(Wu et al., 2005)

neuroanatomy defective, with hiw^{ΔRING.UAS.Tag:TAP}

(Wu et al., 2005)

neuroanatomy defective | adult stage | RU486 conditional, with gbb^UAS.cUa

(Nahm et al., 2013)

neuroanatomy defective | adult stage | RU486 conditional, with tkv^CA.UAS

(Nahm et al., 2013)

neuroanatomy defective | larval stage | RU486 conditional, with ewg^UAS.cHa

(Haussmann et al., 2008)

neuroanatomy defective | larval stage | RU486 conditional, with p38b^JF03341

(Klinedinst et al., 2013)

neuroanatomy defective | larval stage | RU486 conditional, with wnd^GD13786

(Klinedinst et al., 2013)

neuroanatomy defective | larval stage | RU486 conditional, with wnd^JF02675

(Klinedinst et al., 2013)

neuroanatomy defective | RU486 conditional, with Lar^cyto.UAS

(Kaufmann et al., 2002)

neuroanatomy defective | RU486 conditional, with stai^{dsRNA.UAS.WIZ}

(Graf et al., 2011)

neuroanatomy defective | RU486 conditional, with stai^UAS.cBa

(Graf et al., 2011)

neuroanatomy defective | third instar larval stage, with Rac1^UAS.Tag:MYC

(Ball et al., 2010)

neuroanatomy defective | third instar larval stage | RU486 conditional, with Rab3^{N134I.UAS.cCa}

(Chen et al., 2015)

neuroanatomy defective | third instar larval stage | RU486 conditional, with Rab3^Q80L.UAS

(Chen et al., 2015)

neuroanatomy defective | third instar larval stage | RU486 conditional, with Rab3^T35N.UAS

(Chen et al., 2015)

neurophysiology defective, with brp^UAS.GFP

(Tsurudome et al., 2010)

neurophysiology defective | progressive | RU486 conditional, with Hsap\APP^{Arctic.UAS.Tag:SS(nec)}

(Sofola et al., 2010)

neurophysiology defective | RU486 conditional, with Sh^{DN.EKI.UAS.GFP(GL)}

(Mosca et al., 2005)

oxidative stress response defective | adult stage | RU486 conditional, with Mgat1^UAS.cSa

(Sarkar et al., 2010)

paralytic | adult stage | :heat sensitive | RU486 conditional, with Disc\RFP^{mCherry.ppk29.3'UTR.UAS}

(Zheng et al., 2014)

paralytic | adult stage | :heat sensitive | RU486 conditional, with ppk29^3'UTR.UAS

(Zheng et al., 2014)

partially lethal - majority live | male | RU486 conditional, with BacA\p35^UAS.cHa

(Shen et al., 2009)

short lived, with Hsap\APP^{Arctic.UAS.Tag:SS(nec)}

(Sofola-Adesakin et al., 2014)

short lived, with Hsap\ATXN3^70Q.UAS

(Sowa et al., 2018)

short lived | :RU486 conditional | heat sensitive, with Hsap\MAPT^UAS.2N4R.wt

(Gorsky et al., 2016)

short lived | drug conditional, with SdhC^I71E.UAS

(Tsuda et al., 2007)

short lived | female | RU486 conditional, with mir-125^UAS.cCa

(Gendron and Pletcher, 2017)

short lived | male | RU486 conditional, with mir-let7^UAS.cCa

(Gendron and Pletcher, 2017)

short lived | RU486 conditional, with Ahcy^HMC03222

(Parkhitko et al., 2016)

short lived | RU486 conditional, with BacA\p35^UAS.cHa

(Shen et al., 2009)

short lived | RU486 conditional, with for^P1.UAS

(Kanao et al., 2012)

short lived | RU486 conditional, with Hsap\APP^{Arctic.UAS.Tag:SS(nec)}

(Rogers et al., 2012, Sofola et al., 2010)

short lived | RU486 conditional, with Hsap\APP^{Aβ1-42.arctic.UAS.Tag:SS(nec)}

(Burnouf et al., 2016)

short lived | RU486 conditional, with Hsap\APP^{Aβ40.UAS.Tag:SS(nec).cBa}, Hsap\APP^{Aβ42.UAS.Tag:SS(nec).cBa}

(Burnouf et al., 2015)

short lived | RU486 conditional, with Hsap\APP^{Aβ40.UAS.Tag:SS(nec).cBa}, Hsap\APP^{Aβ43.UAS.Tag:SS(nec).cBa}

(Burnouf et al., 2015)

short lived | RU486 conditional, with Hsap\APP^{Aβ42.UAS.Tag:SS(nec).cBa}

(Burnouf et al., 2015)

short lived | RU486 conditional, with Hsap\APP^{Aβ42.UAS.Tag:SS(nec).cBa}, Hsap\APP^{Aβ43.UAS.Tag:SS(nec).cBa}

(Burnouf et al., 2015)

short lived | RU486 conditional, with Hsap\APP^{Aβ42.UAS.Tag:SS(rPENK)}

(Ling and Salvaterra, 2011)

short lived | RU486 conditional, with Hsap\APP^{Aβ43.UAS.Tag:SS(nec).cBa}

(Burnouf et al., 2015)

short lived | RU486 conditional, with Hsap\ATXN1^82Q.UAS

(Reinhardt et al., 2012)

short lived | RU486 conditional, with Hsap\ATXN3^70Q.UAS

(Reinhardt et al., 2012)

short lived | RU486 conditional, with Hsap\ATXN3^fl.SCA3.UAS

(Ristic et al., 2018)

short lived | RU486 conditional, with Hsap\ATXN3^Q80.HNHH.UAS

(Ristic et al., 2018)

short lived | RU486 conditional, with Hsap\ATXN3^{tr.Q78.UAS.Tag:HA}

(Martin-Lanneree et al., 2006)

short lived | RU486 conditional, with Hsap\ATXN7^{10Q.T.UAS.Tag:NLS(SV40-largeT)}

(Latouche et al., 2007)

short lived | RU486 conditional, with Hsap\ATXN7^{102Q.T.UAS.Tag:NLS(SV40-largeT)}

(Latouche et al., 2007)

short lived | RU486 conditional, with Hsap\FUS^{R521C.UAS.Tag:HA}

(Lanson et al., 2011)

short lived | RU486 conditional, with Hsap\FUS^{UAS.cMa.Tag:HA}

(Miguel et al., 2012)

short lived | RU486 conditional, with Hsap\FUS^UAS.Tag:HA

(Lanson et al., 2011)

short lived | RU486 conditional, with Hsap\MAPT^{K280Q.UAS.2N4R}

(Gorsky et al., 2016)

short lived | RU486 conditional, with Hsap\MAPT^{K280R.UAS.2N4R}

(Gorsky et al., 2016)

short lived | RU486 conditional, with Hsap\TARDBP^{M.UAS.Tag:FLAG}

(Miguel et al., 2011)

short lived | RU486 conditional, with Hsap\TARDBP^mutNES.UAS

(Miguel et al., 2011)

short lived | RU486 conditional, with Hsap\TARDBP^mutNLS.UAS

(Miguel et al., 2011)

short lived | RU486 conditional, with Hsap\TARDBP^UAS.cHa

(Zhan et al., 2013)

short lived | RU486 conditional, with Hsap\UCP3^UAS.cHa

(Humphrey et al., 2009)

short lived | RU486 conditional, with Mgat1^{dsRNA.h-h.UAS}

(Sarkar et al., 2010)

short lived | RU486 conditional, with Mgat1^{dsRNA.t-t.UAS}

(Sarkar et al., 2010)

short lived | RU486 conditional, with Pten^UAS.cGb

(Ford et al., 2007)

short lived | RU486 conditional, with Zzzz\GGGGCC^36.UAS

(Mizielinska et al., 2014)

short lived | RU486 conditional, with Zzzz\GGGGCC^103.UAS

(Mizielinska et al., 2014)

short lived | RU486 conditional, with Zzzz\poly-GA^PO-100.UAS

(Mizielinska et al., 2014)

short lived | RU486 conditional, with Zzzz\poly-GR^PO-100.UAS

(Mizielinska et al., 2014)

short lived | RU486 conditional, with Zzzz\poly-PR^PO-100.UAS

(Mizielinska et al., 2014)

short lived | RU486 conditional, with Zzzz\UGGAA^S.UAS

(Ishiguro et al., 2017)

size defective | third instar larval stage, with Rac1^UAS.Tag:MYC

(Ball et al., 2010)

sleep defective | adult stage | :nutrition conditional | RU486 conditional, with trsn^GD1918

(Murakami et al., 2016)

sleep defective | adult stage | :nutrition conditional | RU486 conditional, with trsn^KK108391

(Murakami et al., 2016)

sleep defective | adult stage | progressive | RU486 conditional, with Hsap\APP^{Aβ42.UAS.Tag:SS(rPENK)}

(Gerstner et al., 2017)

sleep defective | adult stage | RU486 conditional, with Ca-α1T^GD3252

(Jeong et al., 2015)

sleep defective | RU486 conditional, with Cul3^NIG.11861R, Dcr-2^UAS.cDa

(Pfeiffenberger and Allada, 2012)

sleep defective | RU486 conditional, with inc^KK108908

(Pfeiffenberger and Allada, 2012)

sleep defective | RU486 conditional, with nur^{UAS.Tag:FLAG,Tag:HA}

(Toda et al., 2019)

sleep defective | RU486 conditional, with Sik3^S563A.UAS

(Funato et al., 2016)

sleep defective | RU486 conditional, with wake^UAS.cLa

(Liu et al., 2014)

some die during embryonic stage, with Hsap\TARDBP^{M.UAS.Tag:FLAG}

(Miguel et al., 2011)

some die during embryonic stage, with Hsap\TARDBP^mutNES.UAS

(Miguel et al., 2011)

some die during embryonic stage, with Hsap\TARDBP^mutNLS.UAS

(Miguel et al., 2011)

some die during pupal stage | RU486 conditional, with ewg^UAS.cHa

(Haussmann et al., 2008)

starvation stress response defective, with park^UAS.cGa

(Rana et al., 2013)

starvation stress response defective | adult stage | RU486 conditional, with trsn^GD1918

(Murakami et al., 2016)

starvation stress response defective | adult stage | RU486 conditional, with trsn^KK108391

(Murakami et al., 2016)

stress response defective | RU486 conditional, with Hsap\UCP2^UAS.cFa

(Fridell et al., 2005)

thermotaxis behavior defective | RU486 conditional, with Mmus\Prkaca^mC.UAS

(Hong et al., 2008)

thermotaxis behavior defective | RU486 conditional, with Pka-R1^BDK.UAS

(Hong et al., 2008)

uncoordinated | RU486 conditional, with Sh^{DN.EKI.UAS.GFP(GL)}

(Mosca et al., 2005)

viable, with Ctet\tetX^TNT-LC.UAS

(Osterwalder et al., 2001)

viable, with Hsap\UCP3^UAS.cHa

(Humphrey et al., 2009)

viable | RU486 conditional, with Sh^{DN.EKI.UAS.GFP(GL)}

(Mosca et al., 2005)

wound healing defective, with bsk^DN.UAS

(Soares et al., 2014)

wound healing defective, with hep^CA.UAS

(Soares et al., 2014)

Phenotype Manifest In

adult brain, with rpr^UAS.C

(Khurana et al., 2006)

adult brain | RU486 conditional, with gbb^UAS.cUa

(Nahm et al., 2013)

adult brain | RU486 conditional, with tkv^CA.UAS

(Nahm et al., 2013)

bouton | RU486 conditional, with stai^{dsRNA.UAS.WIZ}

(Graf et al., 2011)

bouton | RU486 conditional, with stai^UAS.cBa

(Graf et al., 2011)

bouton | supernumerary | RU486 conditional, with Lar^cyto.UAS

(Kaufmann et al., 2002)

brain, with kuk^UASp.cBa

(Brandt et al., 2008)

brain, with Lam^UAS.cGa

(Brandt et al., 2008)

brain | larval stage, with tll^UAS.cKa

(Kurusu et al., 2009)

brain | pupal stage, with tll^UAS.cKa

(Kurusu et al., 2009)

embryonic/larval neuromuscular junction, with hiw^{HindIII.UAS.Tag:polyHis,Tag:MYC}

(Tian et al., 2011)

embryonic/larval neuromuscular junction, with hiw^{HindIII.UAS.Tag:polyHis,Tag:MYC}, hiw^ND8

(Tian et al., 2011)

embryonic/larval neuromuscular junction, with hiw^ND8/hiw^{HindIII.UAS.Tag:polyHis,Tag:MYC}

(Tian et al., 2011)

embryonic/larval neuromuscular junction, with hiw^ND8/hiw^{ΔN.UAS.Tag:TAP}

(Tian et al., 2011)

embryonic/larval neuromuscular junction, with hiw^ND8/hiw^{ΔPHR.UAS.Tag:TAP}

(Tian et al., 2011)

embryonic/larval neuromuscular junction, with hiw^ND8/hiw^{ΔRCC1.UAS.Tag:TAP}

(Tian et al., 2011)

embryonic/larval neuromuscular junction, with hiw^{ΔN.UAS.Tag:TAP}

(Tian et al., 2011)

embryonic/larval neuromuscular junction, with hiw^{ΔN.UAS.Tag:TAP}, hiw^ND8

(Tian et al., 2011)

embryonic/larval neuromuscular junction, with hiw^{ΔPHR.UAS.Tag:TAP}

(Tian et al., 2011)

embryonic/larval neuromuscular junction, with hiw^{ΔPHR.UAS.Tag:TAP}, hiw^ND8

(Tian et al., 2011)

embryonic/larval neuromuscular junction, with hiw^{ΔRCC1.UAS.Tag:TAP}

(Tian et al., 2011)

embryonic/larval neuromuscular junction, with hiw^{ΔRCC1.UAS.Tag:TAP}, hiw^ND8

(Tian et al., 2011)

embryonic/larval neuromuscular junction | RU486 conditional, with ewg^UAS.cHa

(Haussmann et al., 2008)

embryonic/larval neuromuscular junction | third instar larval stage, with Rac1^UAS.Tag:MYC

(Ball et al., 2010)

embryonic/larval neuromuscular junction | third instar larval stage | RU486 conditional, with Rab3^{N134I.UAS.cCa}

(Chen et al., 2015)

embryonic/larval neuromuscular junction | third instar larval stage | RU486 conditional, with Rab3^Q80L.UAS

(Chen et al., 2015)

embryonic/larval neuromuscular junction | third instar larval stage | RU486 conditional, with Rab3^T35N.UAS

(Chen et al., 2015)

mitochondrion | female limited, with park^UAS.cGa

(Rana et al., 2013)

mitochondrion | RU486 conditional, with Hsap\UCP2^UAS.cFa

(Fridell et al., 2005)

neuromuscular junction, with hiw^UAS.Tag:TAP

(Wu et al., 2005)

neuromuscular junction, with hiw^{ΔRING.UAS.Tag:TAP}

(Wu et al., 2005)

neuromuscular junction | RU486 conditional, with Lar^cyto.UAS

(Kaufmann et al., 2002)

neuromuscular junction | RU486 conditional, with stai^{dsRNA.UAS.WIZ}

(Graf et al., 2011)

NMJ bouton, with hiw^{HindIII.UAS.Tag:polyHis,Tag:MYC}

(Tian et al., 2011)

NMJ bouton, with hiw^{HindIII.UAS.Tag:polyHis,Tag:MYC}, hiw^ND8

(Tian et al., 2011)

NMJ bouton, with hiw^ND8/hiw^{HindIII.UAS.Tag:polyHis,Tag:MYC}

(Tian et al., 2011)

NMJ bouton, with hiw^ND8/hiw^{ΔN.UAS.Tag:TAP}

(Tian et al., 2011)

NMJ bouton, with hiw^ND8/hiw^{ΔPHR.UAS.Tag:TAP}

(Tian et al., 2011)

NMJ bouton, with hiw^ND8/hiw^{ΔRCC1.UAS.Tag:TAP}

(Tian et al., 2011)

NMJ bouton, with hiw^{ΔN.UAS.Tag:TAP}

(Tian et al., 2011)

NMJ bouton, with hiw^{ΔN.UAS.Tag:TAP}, hiw^ND8

(Tian et al., 2011)

NMJ bouton, with hiw^{ΔPHR.UAS.Tag:TAP}

(Tian et al., 2011)

NMJ bouton, with hiw^{ΔPHR.UAS.Tag:TAP}, hiw^ND8

(Tian et al., 2011)

NMJ bouton, with hiw^{ΔRCC1.UAS.Tag:TAP}

(Tian et al., 2011)

NMJ bouton, with hiw^{ΔRCC1.UAS.Tag:TAP}, hiw^ND8

(Tian et al., 2011)

NMJ bouton | larval stage | RU486 conditional, with p38b^JF03341

(Klinedinst et al., 2013)

NMJ bouton | larval stage | RU486 conditional, with wnd^GD13786

(Klinedinst et al., 2013)

NMJ bouton | larval stage | RU486 conditional, with wnd^JF02675

(Klinedinst et al., 2013)

NMJ bouton | RU486 conditional, with ewg^UAS.cHa

(Haussmann et al., 2008)

nucleus | adult stage, with kuk^UASp.cBa

(Brandt et al., 2008)

nucleus | adult stage, with Lam^UAS.cGa

(Brandt et al., 2008)

photoreceptor cell | RU486 conditional, with Hsap\APP^{Aβ42.UAS.Tag:SS(nec).cBa}

(Burnouf et al., 2015)

photoreceptor cell | RU486 conditional, with Hsap\APP^{Aβ43.UAS.Tag:SS(nec).cBa}

(Burnouf et al., 2015)

rhabdomere of eye photoreceptor cell | progressive | RU486 conditional, with Hsap\MAPT^{K280Q.UAS.2N4R}

(Gorsky et al., 2016)

rhabdomere of eye photoreceptor cell | progressive | RU486 conditional, with Hsap\MAPT^{K280R.UAS.2N4R}

(Gorsky et al., 2016)

rhabdomere of eye photoreceptor cell | progressive | RU486 conditional, with Hsap\MAPT^UAS.2N4R.wt

(Gorsky et al., 2016)

synapse, with hiw^{HindIII.UAS.Tag:polyHis,Tag:MYC}

(Tian et al., 2011)

synapse, with hiw^{HindIII.UAS.Tag:polyHis,Tag:MYC}, hiw^ND8

(Tian et al., 2011)

synapse, with hiw^ND8/hiw^{HindIII.UAS.Tag:polyHis,Tag:MYC}

(Tian et al., 2011)

synapse, with hiw^ND8/hiw^{ΔN.UAS.Tag:TAP}

(Tian et al., 2011)

synapse, with hiw^ND8/hiw^{ΔPHR.UAS.Tag:TAP}

(Tian et al., 2011)

synapse, with hiw^ND8/hiw^{ΔRCC1.UAS.Tag:TAP}

(Tian et al., 2011)

synapse, with hiw^UAS.Tag:TAP

(Wu et al., 2005)

synapse, with hiw^{ΔN.UAS.Tag:TAP}

(Tian et al., 2011)

synapse, with hiw^{ΔN.UAS.Tag:TAP}, hiw^ND8

(Tian et al., 2011)

synapse, with hiw^{ΔPHR.UAS.Tag:TAP}

(Tian et al., 2011)

synapse, with hiw^{ΔPHR.UAS.Tag:TAP}, hiw^ND8

(Tian et al., 2011)

synapse, with hiw^{ΔRCC1.UAS.Tag:TAP}

(Tian et al., 2011)

synapse, with hiw^{ΔRCC1.UAS.Tag:TAP}, hiw^ND8

(Tian et al., 2011)

synapse, with hiw^{ΔRING.UAS.Tag:TAP}

(Wu et al., 2005)

synapse | RU486 conditional, with stai^{dsRNA.UAS.WIZ}

(Graf et al., 2011)

synapse | RU486 conditional, with stai^UAS.cBa

(Graf et al., 2011)

terminal bouton, with hiw^UAS.Tag:TAP

(Wu et al., 2005)

terminal bouton, with hiw^{ΔRING.UAS.Tag:TAP}

(Wu et al., 2005)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Hsap\ATXN3^70Q.UAS, Scer\GAL4^{elav.Switch.PO} has short lived phenotype, enhanceable by emb^JF01311, Scer\GAL4^{elav.Switch.PO}

(Sowa et al., 2018)

Hsap\TARDBP^UAS.cEa, Scer\GAL4^{elav.Switch.PO} has locomotor behavior defective | adult stage | RU486 conditional phenotype, enhanceable by Hsap\ATXN2^32Q.UAS, Scer\GAL4^{elav.Switch.PO}

(Kim et al., 2014)

Hsap\TARDBP^UAS.cEa, Scer\GAL4^{elav.Switch.PO} has locomotor behavior defective | adult stage | RU486 conditional phenotype, enhanceable by PPP1R15^HMS00811, Scer\GAL4^{elav.Switch.PO}

(Kim et al., 2014)

Scer\GAL4^{elav.Switch.PO}, for^P1.UAS, foxo^UAS.cPa has locomotor behavior defective | adult stage | RU486 conditional phenotype, enhanceable | RU486 conditional by Lrrk^I1915T.UAS, Scer\GAL4^{elav.Switch.PO}

(Kanao et al., 2012)

Scer\GAL4^{elav.Switch.PO}, for^P1.UAS, foxo^UAS.cPa has neuroanatomy defective | adult stage | RU486 conditional phenotype, enhanceable | RU486 conditional by Lrrk^I1915T.UAS, Scer\GAL4^{elav.Switch.PO}

(Kanao et al., 2012)

Hsap\ATXN7^{102Q.T.UAS.Tag:NLS(SV40-largeT)}, Scer\GAL4^{elav.Switch.PO} has short lived | RU486 conditional phenotype, enhanceable by Diap1^j5C8

(Latouche et al., 2007)

Hsap\ATXN7^{102Q.T.UAS.Tag:NLS(SV40-largeT)}, Scer\GAL4^{elav.Switch.PO} has short lived | RU486 conditional phenotype, enhanceable by nej^EP950

(Latouche et al., 2007)

Hsap\ATXN7^{102Q.T.UAS.Tag:NLS(SV40-largeT)}, Scer\GAL4^{elav.Switch.PO} has short lived | RU486 conditional phenotype, enhanceable by HDAC1^EP3672, Scer\GAL4^{elav.Switch.PO}

(Latouche et al., 2007)

Hsap\ATXN7^{102Q.T.UAS.Tag:NLS(SV40-largeT)}, Scer\GAL4^{elav.Switch.PO} has short lived | RU486 conditional phenotype, enhanceable by mub^EP3623, Scer\GAL4^{elav.Switch.PO}

(Latouche et al., 2007)

NOT Enhanced by

Statement

Reference

Hsap\ATXN3^70Q.UAS, Scer\GAL4^{elav.Switch.PO} has short lived phenotype, non-enhanceable by cdm^JF01428, Scer\GAL4^{elav.Switch.PO}

(Sowa et al., 2018)

Hsap\ATXN3^70Q.UAS, Scer\GAL4^{elav.Switch.PO} has short lived phenotype, non-enhanceable by Kap-α3^UASp.cMa, Scer\GAL4^{elav.Switch.PO}

(Sowa et al., 2018)

Hsap\ATXN3^70Q.UAS, Scer\GAL4^{elav.Switch.PO} has locomotor behavior defective | adult stage phenotype, non-enhanceable by cdm^GS17666, Scer\GAL4^{elav.Switch.PO}

(Sowa et al., 2018)

Hsap\ATXN3^70Q.UAS, Scer\GAL4^{elav.Switch.PO} has locomotor behavior defective | adult stage phenotype, non-enhanceable by emb^JF01311, Scer\GAL4^{elav.Switch.PO}

(Sowa et al., 2018)

Hsap\ATXN3^70Q.UAS, Scer\GAL4^{elav.Switch.PO} has locomotor behavior defective | adult stage phenotype, non-enhanceable by Kap-α3^UASp.cMa, Scer\GAL4^{elav.Switch.PO}

(Sowa et al., 2018)

Hsap\APP^{Aβ1-42.arctic.UAS.Tag:SS(nec)}, Scer\GAL4^{elav.Switch.PO} has short lived | RU486 conditional phenotype, non-enhanceable by tau^KO/tau^KO

(Burnouf et al., 2016)

Hsap\TARDBP^UAS.cEa, Scer\GAL4^{elav.Switch.PO} has locomotor behavior defective | adult stage | RU486 conditional phenotype, non-enhanceable by Hsap\ATXN2^{32Q.ΔPAM2.UAS.Tag:MYC}, Scer\GAL4^{elav.Switch.PO}

(Kim et al., 2014)

Suppressed by

Statement

Reference

Hsap\ATXN3^70Q.UAS, Scer\GAL4^{elav.Switch.PO} has short lived phenotype, suppressible | partially by emb^EY08770, Scer\GAL4^{elav.Switch.PO}

(Sowa et al., 2018)

Hsap\ATXN3^70Q.UAS, Scer\GAL4^{elav.Switch.PO} has short lived phenotype, suppressible | partially by Kap-α3^JF02686, Scer\GAL4^{elav.Switch.PO}

(Sowa et al., 2018)

Hsap\ATXN3^70Q.UAS, Scer\GAL4^{elav.Switch.PO} has short lived phenotype, suppressible | partially by Kap-α3^KK101268, Scer\GAL4^{elav.Switch.PO}

(Sowa et al., 2018)

Hsap\ATXN3^70Q.UAS, Scer\GAL4^{elav.Switch.PO} has locomotor behavior defective | adult stage phenotype, suppressible | partially by emb^EY08770, Scer\GAL4^{elav.Switch.PO}

(Sowa et al., 2018)

Hsap\ATXN3^70Q.UAS, Scer\GAL4^{elav.Switch.PO} has locomotor behavior defective | adult stage phenotype, suppressible by Kap-α3^JF02686, Scer\GAL4^{elav.Switch.PO}

(Sowa et al., 2018)

Hsap\TARDBP^UAS.cEa, Scer\GAL4^{elav.Switch.PO} has locomotor behavior defective | adult stage | RU486 conditional phenotype, suppressible by pAbp^JF03104, Scer\GAL4^{elav.Switch.PO}

(Kim et al., 2014)

Hsap\TARDBP^UAS.cEa, Scer\GAL4^{elav.Switch.PO} has locomotor behavior defective | adult stage | RU486 conditional phenotype, suppressible | partially by PEK^GL00030, Scer\GAL4^{elav.Switch.PO}

(Kim et al., 2014)

Hsap\TARDBP^UAS.cEa, Scer\GAL4^{elav.Switch.PO} has locomotor behavior defective | adult stage | RU486 conditional phenotype, suppressible | partially by Rox8^HMS00472, Scer\GAL4^{elav.Switch.PO}

(Kim et al., 2014)

Scer\GAL4^{elav.Switch.PO}, for^P1.UAS has short lived | RU486 conditional phenotype, suppressible | partially by foxo²¹/foxo[+]

(Kanao et al., 2012)

Scer\GAL4^{elav.Switch.PO}, for^P1.UAS has locomotor behavior defective | adult stage | RU486 conditional phenotype, suppressible | partially by foxo²¹/foxo[+]

(Kanao et al., 2012)

Hsap\FUS^{UAS.cMa.Tag:HA}, Scer\GAL4^{elav.Switch.PO} has short lived | RU486 conditional phenotype, suppressible | RU486 conditional by Hsap\HSPA1L^UAS.cWa, Scer\GAL4^{elav.Switch.PO}

(Miguel et al., 2012)

Rac1^UAS.Tag:MYC, Scer\GAL4^{elav.Switch.PO} has neuroanatomy defective | third instar larval stage phenotype, suppressible by Mad^k00237/Mad¹

(Ball et al., 2010)

Lrrk^I1915T.UAS, Scer\GAL4^{elav.Switch.PO}, foxo^UAS.cKb has neuroanatomy defective | adult stage | RU486 conditional phenotype, suppressible by W[+]/hid¹

(Kanao et al., 2010)

Hsap\APP^{Arctic.UAS.Tag:SS(nec)}, Scer\GAL4^{elav.Switch.PO} has locomotor behavior defective | adult stage | progressive | RU486 conditional phenotype, suppressible by tau^MR22/tau^EP3203

(Sofola et al., 2010)

Hsap\APP^{Arctic.UAS.Tag:SS(nec)}, Scer\GAL4^{elav.Switch.PO} has short lived | RU486 conditional phenotype, suppressible | partially by sgg^S9E.UAS, Scer\GAL4^{elav.Switch.PO}

(Sofola et al., 2010)

Hsap\APP^{Arctic.UAS.Tag:SS(nec)}, Scer\GAL4^{elav.Switch.PO} has locomotor behavior defective | adult stage | progressive | RU486 conditional phenotype, suppressible by sgg^S9E.UAS, Scer\GAL4^{elav.Switch.PO}

(Sofola et al., 2010)

Scer\GAL4^{elav.Switch.PO}, brp^UAS.GFP has neurophysiology defective phenotype, suppressible by Df(2R)Exel6285/+

(Tsurudome et al., 2010)

Scer\GAL4^{elav.Switch.PO}, tll^UAS.cKa has cell cycle defective | larval stage phenotype, suppressible by Scer\GAL4^{elav.Switch.PO}/pros^UAS.cMa

(Kurusu et al., 2009)

Scer\GAL4^{elav.Switch.PO}, pros^UAS.cMa has cell cycle defective | larval stage phenotype, suppressible by Scer\GAL4^{elav.Switch.PO}, pros^UAS.cMa

(Kurusu et al., 2009)

Hsap\ATXN7^{102Q.T.UAS.Tag:NLS(SV40-largeT)}, Scer\GAL4^{elav.Switch.PO} has short lived | RU486 conditional phenotype, suppressible by Uba1^UY3010, Scer\GAL4^{elav.Switch.PO}

(Latouche et al., 2007)

Hsap\ATXN7^{102Q.T.UAS.Tag:NLS(SV40-largeT)}, Scer\GAL4^{elav.Switch.PO} has short lived | RU486 conditional phenotype, suppressible by Rpn11^BG01694

(Latouche et al., 2007)

Hsap\ATXN7^{102Q.T.UAS.Tag:NLS(SV40-largeT)}, Scer\GAL4^{elav.Switch.PO} has short lived | RU486 conditional phenotype, suppressible by Diap1^UY1156, Scer\GAL4^{elav.Switch.PO}

(Latouche et al., 2007)

Hsap\ATXN7^{102Q.T.UAS.Tag:NLS(SV40-largeT)}, Scer\GAL4^{elav.Switch.PO} has short lived | RU486 conditional phenotype, suppressible by Diap1^EY00710, Scer\GAL4^{elav.Switch.PO}

(Latouche et al., 2007)

Hsap\ATXN7^{102Q.T.UAS.Tag:NLS(SV40-largeT)}, Scer\GAL4^{elav.Switch.PO} has short lived | RU486 conditional phenotype, suppressible by ced-6^KG03411a

(Latouche et al., 2007)

Hsap\ATXN7^{102Q.T.UAS.Tag:NLS(SV40-largeT)}, Scer\GAL4^{elav.Switch.PO} has short lived | RU486 conditional phenotype, suppressible by Hsc70-3^UAS.cEa, Scer\GAL4^{elav.Switch.PO}

(Latouche et al., 2007)

Hsap\ATXN7^{102Q.T.UAS.Tag:NLS(SV40-largeT)}, Scer\GAL4^{elav.Switch.PO} has short lived | RU486 conditional phenotype, suppressible by Taf10^KG07031

(Latouche et al., 2007)

Hsap\ATXN7^{102Q.T.UAS.Tag:NLS(SV40-largeT)}, Scer\GAL4^{elav.Switch.PO} has short lived | RU486 conditional phenotype, suppressible by Nipped-A^NC116

(Latouche et al., 2007)

Hsap\ATXN7^{102Q.T.UAS.Tag:NLS(SV40-largeT)}, Scer\GAL4^{elav.Switch.PO} has short lived | RU486 conditional phenotype, suppressible by Atx2⁰⁶⁴⁹⁰

(Latouche et al., 2007)

Hsap\ATXN3^{tr.Q78.UAS.Tag:HA}, Scer\GAL4^{elav.Switch.PO} has short lived | RU486 conditional phenotype, suppressible | partially by Mlf^UAS.cFa, Scer\GAL4^{elav.Switch.PO}

(Martin-Lanneree et al., 2006)

Hsap\ATXN3^{tr.Q78.UAS.Tag:HA}, Scer\GAL4^{elav.Switch.PO} has short lived | RU486 conditional phenotype, suppressible | partially by Mlf^UAS.cKa, Scer\GAL4^{elav.Switch.PO}

(Martin-Lanneree et al., 2006)

Scer\GAL4^{elav.Switch.PO}, Sh^{SDN.Scer\UAS.T:Avic\GFP-GL}/Sh^{DN.EKI.UAS.GFP(GL)} has uncoordinated | RU486 conditional phenotype, suppressible by mle^nap-ts1

(Mosca et al., 2005)

Scer\GAL4^{elav.Switch.PO}, Sh^{SDN.Scer\UAS.T:Avic\GFP-GL}/Sh^{DN.EKI.UAS.GFP(GL)} has hyperactive | RU486 conditional phenotype, suppressible by mle^nap-ts1

(Mosca et al., 2005)

NOT suppressed by

Statement

Reference

Scer\GAL4^{elav.Switch.PO}, nur^{UAS.Tag:FLAG,Tag:HA} has sleep defective | RU486 conditional phenotype, non-suppressible by Hsap\KCNJ2^lexAop.EGFP/Ecol\lexA^GMR23E10

(Toda et al., 2019)

Hsap\ATXN3^70Q.UAS, Scer\GAL4^{elav.Switch.PO} has short lived phenotype, non-suppressible by cdm^GS17666, Scer\GAL4^{elav.Switch.PO}

(Sowa et al., 2018)

Hsap\ATXN3^70Q.UAS, Scer\GAL4^{elav.Switch.PO} has locomotor behavior defective | adult stage phenotype, non-suppressible by cdm^JF01428, Scer\GAL4^{elav.Switch.PO}

(Sowa et al., 2018)

Hsap\APP^{Aβ1-42.arctic.UAS.Tag:SS(nec)}, Scer\GAL4^{elav.Switch.PO} has short lived | RU486 conditional phenotype, non-suppressible by tau^KO/tau^KO

(Burnouf et al., 2016)

Hsap\ATXN3^{tr.Q78.UAS.Tag:HA}, Scer\GAL4^{elav.Switch.PO} has short lived | RU486 conditional phenotype, non-suppressible by Mlf[+]/Mlf^ΔC1

(Martin-Lanneree et al., 2006)

Hsap\ATXN3^{tr.Q78.UAS.Tag:HA}, Scer\GAL4^{elav.Switch.PO} has short lived | RU486 conditional phenotype, non-suppressible by Mlf^Δ5-3/Mlf[+]

(Martin-Lanneree et al., 2006)

Enhancer of

Statement

Reference

emb^JF01311, Scer\GAL4^{elav.Switch.PO} is an enhancer of short lived phenotype of Hsap\ATXN3^70Q.UAS, Scer\GAL4^{elav.Switch.PO}

(Sowa et al., 2018)

Hsap\ATXN2^32Q.UAS, Scer\GAL4^{elav.Switch.PO} is an enhancer of locomotor behavior defective | adult stage | RU486 conditional phenotype of Hsap\TARDBP^UAS.cEa, Scer\GAL4^{elav.Switch.PO}

(Kim et al., 2014)

PPP1R15^HMS00811, Scer\GAL4^{elav.Switch.PO} is an enhancer of locomotor behavior defective | adult stage | RU486 conditional phenotype of Hsap\TARDBP^UAS.cEa, Scer\GAL4^{elav.Switch.PO}

(Kim et al., 2014)

Lrrk^I1915T.UAS, Scer\GAL4^{elav.Switch.PO} is an enhancer | RU486 conditional of locomotor behavior defective | adult stage | RU486 conditional phenotype of Scer\GAL4^{elav.Switch.PO}, for^P1.UAS, foxo^UAS.cPa

(Kanao et al., 2012)

Lrrk^I1915T.UAS, Scer\GAL4^{elav.Switch.PO} is an enhancer | RU486 conditional of neuroanatomy defective | adult stage | RU486 conditional phenotype of Scer\GAL4^{elav.Switch.PO}, for^P1.UAS, foxo^UAS.cPa

(Kanao et al., 2012)

Scer\GAL4^{elav.Switch.PO}/dnc^UAS.cCa is an enhancer of neurophysiology defective | recessive | third instar larval stage phenotype of Ent2^P124

(Knight et al., 2010)

HDAC1^EP3672, Scer\GAL4^{elav.Switch.PO} is an enhancer of short lived | RU486 conditional phenotype of Hsap\ATXN7^{102Q.T.UAS.Tag:NLS(SV40-largeT)}, Scer\GAL4^{elav.Switch.PO}

(Latouche et al., 2007)

mub^EP3623, Scer\GAL4^{elav.Switch.PO} is an enhancer of short lived | RU486 conditional phenotype of Hsap\ATXN7^{102Q.T.UAS.Tag:NLS(SV40-largeT)}, Scer\GAL4^{elav.Switch.PO}

(Latouche et al., 2007)

NOT Enhancer of

Statement

Reference

cdm^JF01428, Scer\GAL4^{elav.Switch.PO} is a non-enhancer of short lived phenotype of Hsap\ATXN3^70Q.UAS, Scer\GAL4^{elav.Switch.PO}

(Sowa et al., 2018)

Kap-α3^UASp.cMa, Scer\GAL4^{elav.Switch.PO} is a non-enhancer of short lived phenotype of Hsap\ATXN3^70Q.UAS, Scer\GAL4^{elav.Switch.PO}

(Sowa et al., 2018)

cdm^GS17666, Scer\GAL4^{elav.Switch.PO} is a non-enhancer of locomotor behavior defective | adult stage phenotype of Hsap\ATXN3^70Q.UAS, Scer\GAL4^{elav.Switch.PO}

(Sowa et al., 2018)

emb^JF01311, Scer\GAL4^{elav.Switch.PO} is a non-enhancer of locomotor behavior defective | adult stage phenotype of Hsap\ATXN3^70Q.UAS, Scer\GAL4^{elav.Switch.PO}

(Sowa et al., 2018)

Kap-α3^UASp.cMa, Scer\GAL4^{elav.Switch.PO} is a non-enhancer of locomotor behavior defective | adult stage phenotype of Hsap\ATXN3^70Q.UAS, Scer\GAL4^{elav.Switch.PO}

(Sowa et al., 2018)

Hsap\ATXN2^{32Q.ΔPAM2.UAS.Tag:MYC}, Scer\GAL4^{elav.Switch.PO} is a non-enhancer of locomotor behavior defective | adult stage | RU486 conditional phenotype of Hsap\TARDBP^UAS.cEa, Scer\GAL4^{elav.Switch.PO}

(Kim et al., 2014)

Suppressor of

Statement

Reference

emb^EY08770, Scer\GAL4^{elav.Switch.PO} is a suppressor | partially of short lived phenotype of Hsap\ATXN3^70Q.UAS, Scer\GAL4^{elav.Switch.PO}

(Sowa et al., 2018)

Kap-α3^JF02686, Scer\GAL4^{elav.Switch.PO} is a suppressor | partially of short lived phenotype of Hsap\ATXN3^70Q.UAS, Scer\GAL4^{elav.Switch.PO}

(Sowa et al., 2018)

Kap-α3^KK101268, Scer\GAL4^{elav.Switch.PO} is a suppressor | partially of short lived phenotype of Hsap\ATXN3^70Q.UAS, Scer\GAL4^{elav.Switch.PO}

(Sowa et al., 2018)

emb^EY08770, Scer\GAL4^{elav.Switch.PO} is a suppressor | partially of locomotor behavior defective | adult stage phenotype of Hsap\ATXN3^70Q.UAS, Scer\GAL4^{elav.Switch.PO}

(Sowa et al., 2018)

Kap-α3^JF02686, Scer\GAL4^{elav.Switch.PO} is a suppressor of locomotor behavior defective | adult stage phenotype of Hsap\ATXN3^70Q.UAS, Scer\GAL4^{elav.Switch.PO}

(Sowa et al., 2018)

Scer\GAL4^{elav.Switch.PO}/Rac1^V12.UAS is a suppressor | RU486 conditional of learning defective | adult stage phenotype of Fmr1^5-HA-1014

(Dong et al., 2016)

pAbp^JF03104, Scer\GAL4^{elav.Switch.PO} is a suppressor of locomotor behavior defective | adult stage | RU486 conditional phenotype of Hsap\TARDBP^UAS.cEa, Scer\GAL4^{elav.Switch.PO}

(Kim et al., 2014)

PEK^GL00030, Scer\GAL4^{elav.Switch.PO} is a suppressor | partially of locomotor behavior defective | adult stage | RU486 conditional phenotype of Hsap\TARDBP^UAS.cEa, Scer\GAL4^{elav.Switch.PO}

(Kim et al., 2014)

Rox8^HMS00472, Scer\GAL4^{elav.Switch.PO} is a suppressor | partially of locomotor behavior defective | adult stage | RU486 conditional phenotype of Hsap\TARDBP^UAS.cEa, Scer\GAL4^{elav.Switch.PO}

(Kim et al., 2014)

Hsap\HSPA1L^UAS.cWa, Scer\GAL4^{elav.Switch.PO} is a suppressor | RU486 conditional of short lived | RU486 conditional phenotype of Hsap\FUS^{UAS.cMa.Tag:HA}, Scer\GAL4^{elav.Switch.PO}

(Miguel et al., 2012)

Scer\GAL4^{elav.Switch.PO}/Hsap\SPAST^UAS.Venus is a suppressor | partially of eclosion defective phenotype of spas^5.75

(Du et al., 2010)

Scer\GAL4^{elav.Switch.PO}, Hsap\SPAST^{R388.UAS.Venus}, Hsap\SPAST^UAS.Venus is a suppressor | partially of eclosion defective phenotype of spas^5.75

(Du et al., 2010)

Scer\GAL4^{elav.Switch.PO}, Hsap\SPAST^{R388.UAS.Venus}, Hsap\SPAST^UAS.Venus is a suppressor | partially of locomotor behavior defective | adult stage phenotype of spas^5.75

(Du et al., 2010)

Scer\GAL4^{elav.Switch.PO}/Hsap\SPAST^{R388.UAS.Venus} is a suppressor | partially of eclosion defective phenotype of spas^5.75

(Du et al., 2010)

Scer\GAL4^{elav.Switch.PO}/Hsap\SPAST^R431STOP.UAS is a suppressor | partially of eclosion defective phenotype of spas^5.75

(Du et al., 2010)

Scer\GAL4^{elav.Switch.PO}, Hsap\SPAST^{L44.UAS.T:Avic\GFP-CFP}, Hsap\SPAST^UAS.Venus is a suppressor | partially of eclosion defective phenotype of spas^5.75

(Du et al., 2010)

Scer\GAL4^{elav.Switch.PO}, Hsap\SPAST^{L44.UAS.T:Avic\GFP-CFP}, Hsap\SPAST^UAS.Venus is a suppressor | partially of locomotor behavior defective | adult stage phenotype of spas^5.75

(Du et al., 2010)

Scer\GAL4^{elav.Switch.PO}/Hsap\SPAST^{L44.UAS.T:Avic\GFP-CFP} is a suppressor | partially of eclosion defective phenotype of spas^5.75

(Du et al., 2010)

Scer\GAL4^{elav.Switch.PO}, Hsap\SPAST^{L44.UAS.T:Avic\GFP-CFP}, Hsap\SPAST^{R388.UAS.Venus} is a suppressor | partially of eclosion defective phenotype of spas^5.75

(Du et al., 2010)

Scer\GAL4^{elav.Switch.PO}/Hsap\SPAST^Q45.UAS is a suppressor | partially of eclosion defective phenotype of spas^5.75

(Du et al., 2010)

Scer\GAL4^{elav.Switch.PO}, Hsap\SPAST^{R388.UAS.Venus}, Hsap\SPAST^Q45.UAS is a suppressor | partially of eclosion defective phenotype of spas^5.75

(Du et al., 2010)

sgg^S9E.UAS, Scer\GAL4^{elav.Switch.PO} is a suppressor | partially of short lived | RU486 conditional phenotype of Hsap\APP^{Arctic.UAS.Tag:SS(nec)}, Scer\GAL4^{elav.Switch.PO}

(Sofola et al., 2010)

sgg^S9E.UAS, Scer\GAL4^{elav.Switch.PO} is a suppressor of locomotor behavior defective | adult stage | progressive | RU486 conditional phenotype of Hsap\APP^{Arctic.UAS.Tag:SS(nec)}, Scer\GAL4^{elav.Switch.PO}

(Sofola et al., 2010)

Scer\GAL4^{elav.Switch.PO}/pros^UAS.cMa is a suppressor of cell cycle defective | larval stage phenotype of Scer\GAL4^{elav.Switch.PO}, tll^UAS.cKa

(Kurusu et al., 2009)

Scer\GAL4^{elav.Switch.PO}, pros^UAS.cMa is a suppressor of cell cycle defective | larval stage phenotype of Scer\GAL4^{elav.Switch.PO}, pros^UAS.cMa

(Kurusu et al., 2009)

Uba1^UY3010, Scer\GAL4^{elav.Switch.PO} is a suppressor of short lived | RU486 conditional phenotype of Hsap\ATXN7^{102Q.T.UAS.Tag:NLS(SV40-largeT)}, Scer\GAL4^{elav.Switch.PO}

(Latouche et al., 2007)

Diap1^UY1156, Scer\GAL4^{elav.Switch.PO} is a suppressor of short lived | RU486 conditional phenotype of Hsap\ATXN7^{102Q.T.UAS.Tag:NLS(SV40-largeT)}, Scer\GAL4^{elav.Switch.PO}

(Latouche et al., 2007)

Diap1^EY00710, Scer\GAL4^{elav.Switch.PO} is a suppressor of short lived | RU486 conditional phenotype of Hsap\ATXN7^{102Q.T.UAS.Tag:NLS(SV40-largeT)}, Scer\GAL4^{elav.Switch.PO}

(Latouche et al., 2007)

Hsc70-3^UAS.cEa, Scer\GAL4^{elav.Switch.PO} is a suppressor of short lived | RU486 conditional phenotype of Hsap\ATXN7^{102Q.T.UAS.Tag:NLS(SV40-largeT)}, Scer\GAL4^{elav.Switch.PO}

(Latouche et al., 2007)

Mlf^UAS.cFa, Scer\GAL4^{elav.Switch.PO} is a suppressor | partially of short lived | RU486 conditional phenotype of Hsap\ATXN3^{tr.Q78.UAS.Tag:HA}, Scer\GAL4^{elav.Switch.PO}

(Martin-Lanneree et al., 2006)

Mlf^UAS.cKa, Scer\GAL4^{elav.Switch.PO} is a suppressor | partially of short lived | RU486 conditional phenotype of Hsap\ATXN3^{tr.Q78.UAS.Tag:HA}, Scer\GAL4^{elav.Switch.PO}

(Martin-Lanneree et al., 2006)

Scer\GAL4^{elav.Switch.PO}/esg^EP2009 is a suppressor | RU486 conditional | partially of bang sensitive phenotype of eas²

(Hekmat-Scafe et al., 2005)

NOT Suppressor of

Statement

Reference

cdm^GS17666, Scer\GAL4^{elav.Switch.PO} is a non-suppressor of short lived phenotype of Hsap\ATXN3^70Q.UAS, Scer\GAL4^{elav.Switch.PO}

(Sowa et al., 2018)

cdm^JF01428, Scer\GAL4^{elav.Switch.PO} is a non-suppressor of locomotor behavior defective | adult stage phenotype of Hsap\ATXN3^70Q.UAS, Scer\GAL4^{elav.Switch.PO}

(Sowa et al., 2018)

Scer\GAL4^{elav.Switch.PO}/Rac1^N17.UAS is a non-suppressor of learning defective | adult stage phenotype of Fmr1^5-HA-1014

(Dong et al., 2016)

Scer\GAL4^{elav.Switch.PO}, Hsap\SPAST^{L44.UAS.T:Avic\GFP-CFP}, Hsap\SPAST^{R388.UAS.Venus} is a non-suppressor of locomotor behavior defective | adult stage phenotype of spas^5.75

(Du et al., 2010)

Phenotype Manifest In

Enhanced by

Statement

Reference

Scer\GAL4^{elav.Switch.PO}, for^P1.UAS, foxo^UAS.cPa has eye | RU486 conditional phenotype, enhanceable | RU486 conditional by Lrrk^I1915T.UAS, Scer\GAL4^{elav.Switch.PO}

(Kanao et al., 2012)

Suppressed by

Statement

Reference

Scer\GAL4^{elav.Switch.PO}, hiw^{ΔN.UAS.Tag:TAP} has synapse phenotype, suppressible by Rae1^UAS.EGFP, Scer\GAL4^{elav.Switch.PO}

(Tian et al., 2011)

Scer\GAL4^{elav.Switch.PO}, hiw^{ΔN.UAS.Tag:TAP} has NMJ bouton phenotype, suppressible by Rae1^UAS.EGFP, Scer\GAL4^{elav.Switch.PO}

(Tian et al., 2011)

Scer\GAL4^{elav.Switch.PO}, hiw^{ΔN.UAS.Tag:TAP} has embryonic/larval neuromuscular junction phenotype, suppressible by Rae1^UAS.EGFP, Scer\GAL4^{elav.Switch.PO}

(Tian et al., 2011)

Lrrk^I1915T.UAS, Scer\GAL4^{elav.Switch.PO}, foxo^UAS.cKb has dopaminergic neuron | RU486 conditional phenotype, suppressible by W[+]/hid¹

(Kanao et al., 2010)

Lrrk^I1915T.UAS, Scer\GAL4^{elav.Switch.PO}, foxo^UAS.cKb has dopaminergic PPL1 neuron | RU486 conditional phenotype, suppressible by W[+]/hid¹

(Kanao et al., 2010)

Scer\GAL4^{elav.Switch.PO}, tll^UAS.cKa has brain | larval stage phenotype, suppressible by Scer\GAL4^{elav.Switch.PO}/pros^UAS.cMa

(Kurusu et al., 2009)

Scer\GAL4^{elav.Switch.PO}, pros^UAS.cMa has brain | larval stage phenotype, suppressible by Scer\GAL4^{elav.Switch.PO}, pros^UAS.cMa

(Kurusu et al., 2009)

Enhancer of

Statement

Reference

Lrrk^I1915T.UAS, Scer\GAL4^{elav.Switch.PO} is an enhancer | RU486 conditional of eye | RU486 conditional phenotype of Scer\GAL4^{elav.Switch.PO}, for^P1.UAS, foxo^UAS.cPa

(Kanao et al., 2012)

Scer\GAL4^{elav.Switch.PO}/dnc^UAS.cCa is an enhancer of synapse phenotype of Ent2^P124

(Knight et al., 2010)

Suppressor of

Statement

Reference

Scer\GAL4^{elav.Switch.PO}/Hsap\ACSL4^{UAS.L.Tag:MYC} is a suppressor of synapse phenotype of Acsl⁰⁵⁸⁴⁷/Acsl^KO

(Liu et al., 2011)

Rae1^UAS.EGFP, Scer\GAL4^{elav.Switch.PO} is a suppressor of synapse phenotype of Scer\GAL4^{elav.Switch.PO}, hiw^{ΔN.UAS.Tag:TAP}

(Tian et al., 2011)

Rae1^UAS.EGFP, Scer\GAL4^{elav.Switch.PO} is a suppressor of NMJ bouton phenotype of Scer\GAL4^{elav.Switch.PO}, hiw^{ΔN.UAS.Tag:TAP}

(Tian et al., 2011)

Rae1^UAS.EGFP, Scer\GAL4^{elav.Switch.PO} is a suppressor of embryonic/larval neuromuscular junction phenotype of Scer\GAL4^{elav.Switch.PO}, hiw^{ΔN.UAS.Tag:TAP}

(Tian et al., 2011)

Scer\GAL4^{elav.Switch.PO}/Hsap\SPAST^UAS.Venus is a suppressor | partially of NMJ bouton | supernumerary | larval stage phenotype of spas^5.75

(Du et al., 2010)

Scer\GAL4^{elav.Switch.PO}/Hsap\SPAST^UAS.Venus is a suppressor | partially of microtubule | larval stage phenotype of spas^5.75

(Du et al., 2010)

Scer\GAL4^{elav.Switch.PO}, Hsap\SPAST^{R388.UAS.Venus}, Hsap\SPAST^UAS.Venus is a suppressor | partially of NMJ bouton | supernumerary | larval stage phenotype of spas^5.75

(Du et al., 2010)

Scer\GAL4^{elav.Switch.PO}, Hsap\SPAST^{L44.UAS.T:Avic\GFP-CFP}, Hsap\SPAST^UAS.Venus is a suppressor | partially of NMJ bouton | supernumerary | larval stage phenotype of spas^5.75

(Du et al., 2010)

Scer\GAL4^{elav.Switch.PO}, Hsap\SPAST^{L44.UAS.T:Avic\GFP-CFP}, Hsap\SPAST^UAS.Venus is a suppressor | partially of microtubule | larval stage phenotype of spas^5.75

(Du et al., 2010)

Scer\GAL4^{elav.Switch.PO}/Hsap\SPAST^Q45.UAS is a suppressor of NMJ bouton | supernumerary | larval stage phenotype of spas^5.75

(Du et al., 2010)

Scer\GAL4^{elav.Switch.PO}/Hsap\SPAST^Q45.UAS is a suppressor | partially of microtubule | larval stage phenotype of spas^5.75

(Du et al., 2010)

Scer\GAL4^{elav.Switch.PO}, Hsap\SPAST^{R388.UAS.Venus}, Hsap\SPAST^Q45.UAS is a suppressor | partially of NMJ bouton | supernumerary | larval stage phenotype of spas^5.75

(Du et al., 2010)

Scer\GAL4^{elav.Switch.PO}, Hsap\SPAST^{R388.UAS.Venus}, Hsap\SPAST^Q45.UAS is a suppressor | partially of microtubule | larval stage phenotype of spas^5.75

(Du et al., 2010)

Scer\GAL4^{elav.Switch.PO}/pros^UAS.cMa is a suppressor of brain | larval stage phenotype of Scer\GAL4^{elav.Switch.PO}, tll^UAS.cKa

(Kurusu et al., 2009)

Scer\GAL4^{elav.Switch.PO}, pros^UAS.cMa is a suppressor of brain | larval stage phenotype of Scer\GAL4^{elav.Switch.PO}, pros^UAS.cMa

(Kurusu et al., 2009)

NOT Suppressor of

Statement

Reference

Scer\GAL4^{elav.Switch.PO}, Hsap\SPAST^{R388.UAS.Venus}, Hsap\SPAST^UAS.Venus is a non-suppressor of microtubule | larval stage phenotype of spas^5.75

(Du et al., 2010)

Scer\GAL4^{elav.Switch.PO}, Hsap\SPAST^{L44.UAS.T:Avic\GFP-CFP}, Hsap\SPAST^{R388.UAS.Venus} is a non-suppressor of NMJ bouton | supernumerary | larval stage phenotype of spas^5.75

(Du et al., 2010)

Scer\GAL4^{elav.Switch.PO}, Hsap\SPAST^{L44.UAS.T:Avic\GFP-CFP}, Hsap\SPAST^{R388.UAS.Venus} is a non-suppressor of microtubule | larval stage phenotype of spas^5.75

(Du et al., 2010)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Scer\GAL4^{elav.Switch.PO}/Lsm12a^UAS.Tag:FLAG rescues Lsm12a^Δ6

(Lee et al., 2017)

Scer\GAL4^{elav.Switch.PO}/Prosap^UAS.Tag:MYC rescues Prosap^8k

(Wu et al., 2017)

Scer\GAL4^{elav.Switch.PO}, hiw^ND9 rescues hiw^ND9

(Huang et al., 2012)

Scer\GAL4^{elav.Switch.PO}/hiw^UAS.fl rescues hiw^ND9

(Huang et al., 2012)

Scer\GAL4^{elav.Switch.PO}/trio^UAS.cBa rescues trio^6A/trio^S137203

(Ball et al., 2010)

Scer\GAL4^{elav.Switch.PO}/rut^UAS.cZa rescues rut²⁰⁸⁰

(Donlea et al., 2009)

Scer\GAL4^{elav.Switch.PO}/dnc^UAS.cCa rescues dnc¹

(van Swinderen et al., 2009)

Scer\GAL4^{elav.Switch.PO}/dnc^UAS.cCa rescues dnc¹

(van Swinderen, 2007)

Scer\GAL4^{elav.Switch.PO}/hiw^UAS.W.EGFP rescues hiw^ND8

(Wu et al., 2005)

Scer\GAL4^{elav.Switch.PO}/spas^UAS.cSa rescues spas^5.75

(Sherwood et al., 2004)

Scer\GAL4^{elav.Switch.PO}/sbb^UAS.cYa rescues sbb⁰³⁴³²

(Suster et al., 2004)

Partially rescues

Scer\GAL4^{elav.Switch.PO}, tara^s132 partially rescues tara^s132

(Afonso et al., 2015)

Scer\GAL4^{elav.Switch.PO}/qvr^UAS.cWa partially rescues qvr^EY04063

(Chen et al., 2015)

Scer\GAL4^{elav.Switch.PO}/TBPH^UAS.Tag:FLAG partially rescues TBPH^Δ23

(Romano et al., 2014)

Scer\GAL4^{elav.Switch.PO}/Smn^UAS.Tag:FLAG partially rescues Smn^X7

(Imlach et al., 2012)

Scer\GAL4^{elav.Switch.PO}/spas^UAS.CFP partially rescues spas^5.75

(Du et al., 2010)

Scer\GAL4^{elav.Switch.PO}/Mgat1^UAS.cSa partially rescues Mgat1¹

(Sarkar et al., 2010)

Fails to rescue

Scer\GAL4^{elav.Switch.PO}/TBPH^{F-L150-152.UAS} fails to rescue TBPH^Δ23

(Romano et al., 2014)

Scer\GAL4^{elav.Switch.PO}/hiw^ΔRING.UAS fails to rescue hiw^ND9

(Huang et al., 2012)

Scer\GAL4^{elav.Switch.PO}/chico^UAS.cNa fails to rescue chico¹

(Naganos et al., 2012)

Scer\GAL4^{elav.Switch.PO}/Fmr1^UAS.cZa fails to rescue Fmr1^Δ50M

(Gatto and Broadie, 2009)

Comments

Images (0)

Mutant

Wild-type

Stocks (3)

Bloomington

43642

y¹ w^*; P{elav-Switch.O}GSG301

56756

w^*; P{UAS-APP695-N-myc}TW6, P{UAS-BACE1.Exel}1b; P{elav-Switch.O}GSG301

56755

w^*; P{UAS-BACE1.Exel}7b, P{UAS-APP.695.Exel}1, P{elav-Switch.O}GSG301/TM3, Sb¹

Notes on Origin

Discoverer

Comments

The "GeneSwitch" Scer\GAL4 protein produced by Scer\GAL4^{elav.Switch.PO} allows conditional expression of UAS transgenes, dependant on the presence of the activator RU486 (RU486 is thought to activate the protein produced by Scer\GAL4^{elav.Switch.PO} from a transcriptionally inactive to a transcriptionally active form). Expression of UAS transgenes by the Scer\GAL4^{elav.Switch.PO} protein is dose-dependent on RU486 concentration, with low background in the absence of RU486.

(Osterwalder et al., 2001)

The Scer\GAL4^{elav.Switch.PO} driver is leaky during the larval stages (driving expression of a UAS transgene in the absence of RU486).

(Poirier et al., 2008)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Scer\GAL4^{elav.Switch.PO}

Name Synonyms

Secondary FlyBase IDs

References (163)

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