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General Information
Symbol
Scer\GAL4elav.Switch.PO
Species
S. cerevisiae
Name
FlyBase ID
FBal0128065
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
Elav-GeneSwitch, elav-GS, ElavGS, Elav-GS-GAL4, ELAV-GeneSwitch-Gal4, GS-elav, ElavGS-Gal4, GS-elav-Gal4, GSelav, elav-Switch
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference
A 3.5kb fragment of the elav gene (including the elav promoter and the 5' UTR exons 0 and 1) drives expression of the ligand-inducible GAL4::GS driver.
Allele components
Product class / Tool use(s)
Regulatory region(s)
Expression Data
Reporter Expression
distribution deduced from reporter (Gal4 UAS)
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Information
Statement
Reference
Drives mifepristone-inducible expression pan-neuronally at larval and adult stages.
Scer\GAL4elav.Switch.PO drives mifepristone-inducible expression pan-neuronally
Expression is driven pan-neuronally.
 
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference
NOT Enhanced by
Suppressed by
Statement
Reference
Scer\GAL4elav.Switch.PO, forP1.UAS has short lived | RU486 conditional phenotype, suppressible | partially by foxo21/foxo[+]
Scer\GAL4elav.Switch.PO, forP1.UAS has locomotor behavior defective | adult stage | RU486 conditional phenotype, suppressible | partially by foxo21/foxo[+]
NOT suppressed by
Enhancer of
Statement
Reference
NOT Enhancer of
Suppressor of
Statement
Reference
NOT Suppressor of
Phenotype Manifest In
Enhanced by
Statement
Reference
Suppressed by
Enhancer of
Suppressor of
Statement
Reference
NOT Suppressor of
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (3)
Notes on Origin
Discoverer
Comments
Comments
The "GeneSwitch" Scer\GAL4 protein produced by Scer\GAL4elav.Switch.PO allows conditional expression of UAS transgenes, dependant on the presence of the activator RU486 (RU486 is thought to activate the protein produced by Scer\GAL4elav.Switch.PO from a transcriptionally inactive to a transcriptionally active form). Expression of UAS transgenes by the Scer\GAL4elav.Switch.PO protein is dose-dependent on RU486 concentration, with low background in the absence of RU486.
The Scer\GAL4elav.Switch.PO driver is leaky during the larval stages (driving expression of a UAS transgene in the absence of RU486).
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Scer\GAL4elav.Switch.PO
Name Synonyms
Secondary FlyBase IDs
    References (162)