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General Information
Symbol
Dmel\RhoGAP93BdsRNA.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0128103
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of two copies of RhoGAP93B sequence, arranged in an inverted repeat.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of RhoGAP93BdsRNA.Scer\UAS under the control of Scer\GAL4OK107 results in no obvious phenotype. Expression of RhoGAP93BdsRNA.Scer\UAS under the control of Scer\GAL4ey.PB results in a reduction in the size of the eye.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Enhancer of
Additional Comments
Genetic Interactions
Statement
Reference

In robo5/+, sli1/+ transheterozygous embryos, the medial longitudinal pathway occasionally crosses the midline. The addition of RhoGAP93BdsRNA.Scer\UAS (driven by Scer\GAL4elav.PLu) significantly enhances this phenotype. The subsequent addition of RhoGAP93BScer\UAS.cHa suppresses this enhancement.

When RhoGAP93BdsRNA.Scer\UAS is driven by Scer\GAL4elav.PLu in a fraunspecified background no midline crossing defects are seen. When RhoGAP93BdsRNA.Scer\UAS is driven by Scer\GAL4elav.PLu in a Ptp69D4/Ptp10Dunspecified background no midline crossing defects are seen. When RhoGAP93BdsRNA.Scer\UAS is driven by Scer\GAL4elav.PLu in a Ptp69Dunspecified/Ptp10Dunspecified background no midline crossing defects are seen.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer
Comments
Comments

Transcription from the P{UAS-RhoGAP93B-dsRNA} construct should produce RhoGAP93B dsRNA, resulting in dsRNA interference (RNAi) of the RhoGAP93B gene.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
RhoGAP93BdsRNA.Scer\UAS
RhoGAP93BdsRNA.UAS
Name Synonyms
Secondary FlyBase IDs
    References (3)