Allele Dmel\Graf^{dsRNA.Scer\UAS}

General Information
Symbol	Dmel\Graf^{dsRNA.Scer\UAS}	Species	D. melanogaster
Name		FlyBase ID	FBal0128187
Feature type	allele	Created / Updated	2006-08-20/2006-08-20
Associated gene	Dmel\Graf

Allele class
Mutagen	in vitro construct \| regulatory fusion, in vitro construct \| RNAi
Nature of the Allele
Allele class
Mutagen	in vitro construct \| regulatory fusion (Billuart et al., 2001) in vitro construct \| RNAi (Billuart et al., 2001)
Mapped Features and Mutations
Type Symbol & Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Construct: Scer\UAS regulatory sequences drive expression of two copies of Graf sequence, arranged in an inverted repeat. (Billuart et al., 2001)
Assay mode	In transgenic Drosophila (intraspecific) (Billuart et al., 2001)
Carried in construct	P{UAS-Graf-dsRNA} (Billuart et al., 2001, He et al., 2005)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In

Detailed Description
	Statement Reference Expression of Graf^{dsRNA.Scer\UAS} under the control of Scer\GAL4^αTub84B.PL, Scer\GAL4^T80, Scer\GAL4^ey.PB or Scer\GAL4^OK107 results in no obvious phenotype. (Billuart et al., 2001)
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Enhancer of
Statement Reference Graf^{dsRNA.Scer\UAS}, Scer\GAL4^ap-md544 is an enhancer of wing hair \| supernumerary phenotype of Scer\GAL4^ap-md544, trc^{T453A.Scer\UAS} (He et al., 2005)
Additional Comments
Genetic Interactions
Statement Reference Coexpression of Graf[dsRNA.Scer\UAS] greatly enhances the Scer\GAL4[ap-md544]>trc[T453A.Scer\UAS] multiple wing hair phenotype. (He et al., 2005)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 2 )
Bloomington	6425 y¹ w^; P{UAS-Graf-dsRNA}4 6426 y¹ w^; P{UAS-Graf-dsRNA}5.1
Notes on Origin
Discoverer

Comments
	Transcription from the P{UAS-Graf-dsRNA} construct should produce Graf dsRNA, resulting in dsRNA interference (RNAi) of the Graf gene. (Billuart et al., 2001)
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	Graf^{dsRNA.Scer\UAS}
Name Synonym
Secondary FlyBase IDs

References ( 2 )
Research paper	He et al., 2005, Molec. Biol. Cell 16(2): 689--700 The tricornered Ser/Thr protein kinase is regulated by phosphorylation and interacts with furry during Drosophila wing hair development. [FBrf0184141] Billuart et al., 2001, Cell 107(2): 195--207 Regulating axon branch stability. The role of p190 RhoGAP in repressing a retraction signaling pathway. [FBrf0139610]

Allele Dmel\GrafdsRNA.Scer\UAS

Allele Dmel\Graf^{dsRNA.Scer\UAS}