FB2025_01 , released February 20, 2025
Allele: Dmel\wupAPG31
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General Information
Symbol
Dmel\wupAPG31
Species
D. melanogaster
Name
FlyBase ID
FBal0128960
Feature type
allele
Associated gene
Dmel\wupA
Associated Insertion(s)
P{GawB}wupAPG31
Carried in Construct
Also Known As
PG31
Key Links
Genomic Maps

Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Sahota et al., 2009)
Mutagen
Delta2-3 transposase
(Bourbon et al., 2002)
Progenitor genotype
Associated Insertion(s)
P{GawB}wupAPG31
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{GawB}
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous wupAPG31 mutants show nuclear defects in the syncitial embryo. Nuclei in the anterior region of the wupAPG31 mutant embryos either stop dividing or undergo one division less than nuclei at the posterior end.

      (Sahota et al., 2009)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      NOT suppressed by
      Statement
      Reference

      wupAPG31 has lethal | recessive phenotype, non-suppressible by Dp(1;2)CH322-61E2

      (Casas-Tintó and Ferrús, 2021)

      wupAPG31 has lethal | recessive phenotype, non-suppressible by Dp(1;3)CH322-4P16

      (Casas-Tintó and Ferrús, 2021)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      PG31
      (Casas-Tintó and Ferrús, 2021, Sahota et al., 2009)
      wupAPG31
      Name Synonyms
      Secondary FlyBase IDs
        References (4)