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General Information
Symbol
Dmel\tsuEP567
Species
D. melanogaster
Name
FlyBase ID
FBal0128984
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
EP(2)0567, tsu1
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

P{EP} insertion 70bp upstream of the predicted start codon.

P{EP} insertion in the 5' UTR, 72bp upstream of the first translation start site.

Insertion components
P{EP}tsuEP567
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Overexpression of tsuEP567 in the eye under the control of Scer\GAL4GMR.PF does not cause any apparent neurodegeneration in the retina.

Females carrying homozygous germline clones lay eggs which are smaller than wild type and are unfertilised. The actin cytoskeleton (including the ring canals) appears normal in mutant egg chambers and mutant oocytes show the normal anterolateral accumulation of microtubules.

Eggs and embryos derived from females with homozygous follicle cell clones are indistinguishable from wild type. Females containing homozygous germ-line clones lay defective eggs and embryos derived from these eggs fail to hatch.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
NOT Enhancer of
Statement
Reference
Suppressor of
Statement
Reference

tsu[+]/tsuEP567 is a suppressor of visible phenotype of Ras85DV12.sev

NOT Suppressor of
Statement
Reference
Phenotype Manifest In
Enhancer of
Statement
Reference
NOT Enhancer of
Statement
Reference
Suppressor of
Statement
Reference

tsu[+]/tsuEP567 is a suppressor of eye phenotype of Ras85DV12.sev

NOT Suppressor of
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

A tsuEP567 mutant background enhances the moderately rough eye phenotype observed upon expression of mblC.Scer\UAS under the control of Scer\GAL4hs.2sev.

Xenogenetic Interactions
Statement
Reference

tsuEP567 has no effect on the rough eye phenotype caused by expression of Zzzz\CTGi480.Scer\UAS.cGa under the control of Scer\GAL4sev.PU.

Complementation and Rescue Data
Fails to complement
Comments
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer
Comments
Comments

Excision of the P{EP} element can revert the lethal phenotype.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (5)
References (13)