Allele Dmel\trx^EP3541

General Information
Symbol	Dmel\trx^EP3541	Species	D. melanogaster
Name		FlyBase ID	FBal0128989
Feature type	allele	Associated gene	Dmel\trx

Map ( GBrowse )	Untitled Document
Allele class
Mutagen	P-element activity
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	P-element activity (Gene Disruption Project members, 2001-, Pena-Rangel et al., 2002)
Mutations Mapped to the Genome

Type Location Additional Notes References transposable element insertion site 3R:10,103,928..10,103,928 (Gene Disruption Project members, 2001-, Pena-Rangel et al., 2002, Tie et al., 2009, Park and Song, 2008)
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Caused by insertion	P{EP}trx^EP3541 (Gene Disruption Project members, 2001-, Pena-Rangel et al., 2002, Tie et al., 2009, Park and Song, 2008)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In

Detailed Description
	Statement Reference
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement Reference Scer\GAL4^pnr-MD237/trx^EP3541 is an enhancer of visible phenotype of pnr^MD237 (Pena-Rangel et al., 2002)
Suppressor of
Statement Reference trx^EP3541/Scer\GAL4^GMR.PU is a suppressor of visible phenotype of Scer\GAL4^GMR.PU, lok^Scer\UAS.cPb (Park and Song, 2008)
NOT Suppressor of
Statement Reference trx^EP3541, Scer\GAL4^GMR.PU is a non-suppressor of visible phenotype of N^Scer\UAS.cMa, Scer\GAL4^GMR.PU (Park and Song, 2008)
Phenotype Manifest In
Enhancer of
Statement Reference Scer\GAL4^pnr-MD237/trx^EP3541 is an enhancer of chaeta phenotype of pnr^MD237 (Pena-Rangel et al., 2002)
Suppressor of
Statement Reference trx^EP3541/Scer\GAL4^GMR.PU is a suppressor of eye phenotype of Scer\GAL4^GMR.PU, lok^Scer\UAS.cPb (Park and Song, 2008)
NOT Suppressor of
Statement Reference trx^EP3541, Scer\GAL4^GMR.PU is a non-suppressor of eye phenotype of N^Scer\UAS.cMa, Scer\GAL4^GMR.PU (Park and Song, 2008)
Other
Statement Reference Scer\GAL4^pnr-MD237, pnr^MD237, trx^EP3541 has scutellar bristle \| ectopic phenotype (Pena-Rangel et al., 2002) Scer\GAL4^pnr-MD237, pnr^MD237, trx^EP3541 has scutellum phenotype (Pena-Rangel et al., 2002) Scer\GAL4^pnr-MD237, pnr^MD237/pnr[+], trx^EP3541 has scutellar bristle \| ectopic phenotype (Pena-Rangel et al., 2002) Scer\GAL4^pnr-MD237, pnr^MD237/pnr[+], trx^EP3541 has scutellum phenotype (Pena-Rangel et al., 2002)
Additional Comments
Genetic Interactions
Statement Reference Expression of trx[EP3541] suppresses the rough eye phenotype seen when lok[Scer\UAS.cPb] is expressed under the control of Scer\GAL4[GMR.PU]. Expression of trx[EP3541] does not suppress the rough eye phenotype seen when N[Scer\UAS.cMa] is expressed under the control of Scer\GAL4[GMR.PU]. (Park and Song, 2008) pnr^MD237/+ adults expressing trx^EP3541 under the control of Scer\GAL4^pnr-MD237 have deformed scutellum and ectopic scutellar macrochaetae. (Pena-Rangel et al., 2002)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer
	Selected as: a P{EP} insertion line that modifies the pnr^MD237/+ phenotype when expressed using Scer\GAL4^pnr-MD237. (Pena-Rangel et al., 2002)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	trx^EP3541
Name Synonym
Secondary FlyBase IDs

References ( 4 )
Research paper	Tie et al., 2009, Development 136(18): 3131--3141 CBP-mediated acetylation of histone H3 lysine 27 antagonizes Drosophila Polycomb silencing. [FBrf0208543] Park and Song, 2008, Mol. Cells 26(4): 350--355 Genetic screen for genes involved in Chk2 signaling in Drosophila. [FBrf0207160] Pena-Rangel et al., 2002, Genetics 160(3): 1035--1050 A misexpression study examining dorsal thorax formation in Drosophila melanogaster. [FBrf0147055]
Personal communication to FlyBase	Gene Disruption Project members, 2001-, (Computer file) (Computer file) [FBrf0132177]

Allele Dmel\trxEP3541

Allele Dmel\trx^EP3541