FB2025_01 , released February 20, 2025
Allele: Dmel\Vha68-2EP2364
Open Close
General Information
Symbol
Dmel\Vha68-2EP2364
Species
D. melanogaster
Name
FlyBase ID
FBal0130533
Feature type
allele
Associated gene
Dmel\Vha68-2
Associated Insertion(s)
P{EP}Vha68-2EP2364
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Gene Disruption Project members, 2001-)
Progenitor genotype
Associated Insertion(s)
P{EP}Vha68-2EP2364
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{EP}
Regulatory region(s)
UAS
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      exacerbates  amyotrophic lateral sclerosis type 15
      modeled by Ubqn1
      (Şentürk et al., 2019)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Vha68-2EP2364 heterozygotes are viable.

      (Şentürk et al., 2019)

      Induction of Vha68-2EP2364 homozygous whole-eye clones in the third instar larva leads to the absence of eyes in adults.

      (Zhao et al., 2018)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      Vha68-2[+]/Vha68-2EP2364 is an enhancer of increased mortality during development phenotype of Ubqn1

      (Şentürk et al., 2019)
      Suppressor of
      Statement
      Reference

      maskUAS.cZa, Vha68-2[+], Vha68-2EP2364, Scer\GAL4how-24B is a suppressor | partially of lethal - all die before end of P-stage | heat sensitive phenotype of Prosβ61.B.UAS, Scer\GAL4how-24B

      (Zhu et al., 2017)

      Vha68-2[+]/Vha68-2EP2364, Scer\GAL4GMR.PU is a suppressor | partially of visible | heat sensitive phenotype of Ivir\M2UAS.cAa, Scer\GAL4GMR.PU

      (Adamson et al., 2011)
      Other
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      maskUAS.cZa, Vha68-2[+], Vha68-2EP2364, Scer\GAL4how-24B is a suppressor | partially of pupal thorax | heat sensitive phenotype of Prosβ61.B.UAS, Scer\GAL4how-24B

      (Zhu et al., 2017)

      Vha68-2[+]/Vha68-2EP2364, Scer\GAL4GMR.PU is a suppressor | partially of eye | heat sensitive phenotype of Ivir\M2UAS.cAa, Scer\GAL4GMR.PU

      (Adamson et al., 2011)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Vha68-2EP2364
      (Şentürk et al., 2019)
      vha68-2EP2364
      (Zhao et al., 2018, Adamson et al., 2011)
      Name Synonyms
      Secondary FlyBase IDs
        References (5)