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General Information
Symbol
Dmel\SmBBG02775
Species
D. melanogaster
Name
FlyBase ID
FBal0130597
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Insertion components
P{GT1}SmBBG02775
Product class / Tool use(s)
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

Expression of SmBScer\UAS.P\T.cAa under the control of Scer\GAL4tub.PU rescues the lethality of SmBBG02775/SmBSH0509 with an efficiency of 61%.

Expression of SmBR1-7.Scer\UAS.P\T under the control of Scer\GAL4tub.PU rescues the lethality of SmBBG02775/SmBSH0509 with an efficiency of 32%. However, all the rescued flies are completely agametic. Although germ cells can migrate through the midgut epithelium in these embryos, they are unable to coalesce with the gonadal mesoderm.

Expression of SmBR1-7K.Scer\UAS.P\T under the control of Scer\GAL4tub.PU rescues the lethality of SmBBG02775/SmBSH0509 with an efficiency of 28%. However, all the rescued flies are completely agametic. Although germ cells can migrate through the midgut epithelium in these embryos, they are unable to coalesce with the gonadal mesoderm.

Expression of SmBR4-7.Scer\UAS.P\T under the control of Scer\GAL4tub.PU rescues the lethality of SmBBG02775/SmBSH0509 with an efficiency of 37%. Rescued females have smaller ovaries than normal and contain mostly previtellogenic egg chambers. Most egg chambers that have reached the end of previtellogenic development show signs of degeneration, including a condensed nuclear morphology. Embryos derived from the few eggs laid by the rescued females build a normal layer of blastoderm cells, but fail to form pole cells.

Expression of SmBR4-7K.Scer\UAS.P\T under the control of Scer\GAL4tub.PU rescues the lethality of SmBBG02775/SmBSH0509 with an efficiency of 30%. Rescued females have smaller ovaries than normal and contain mostly previtellogenic egg chambers. Most egg chambers that have reached the end of previtellogenic development show signs of degeneration, including a condensed nuclear morphology.

Expression of SmBR1-3K.Scer\UAS.P\T under the control of Scer\GAL4tub.PU rescues the lethality of SmBBG02775/SmBSH0509 with an efficiency of 27%. The rescued animals have no gametes.

Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer

Separable from: a second-site lethal mutation.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (4)