FB2025_01 , released February 20, 2025
Allele: Dmel\SdcBG02774
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General Information
Symbol
Dmel\SdcBG02774
Species
D. melanogaster
Name
FlyBase ID
FBal0130611
Feature type
allele
Associated gene
Dmel\Sdc
Associated Insertion(s)
P{GT1}SdcBG02774
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Gene Disruption Project members, 2001-)
Progenitor genotype
Associated Insertion(s)
P{GT1}SdcBG02774
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{GT1}
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Triacylglycerol (TAG) storage is reduced in homozygous flies (males and females).

      Adult female homozygotes have 21% reduced body weight and exhibit reduced protein and glycogen levels compared to controls. Male homozygous flies do not differ from wild type.

      Female flies lay 42% fewer eggs than controls.

      A 22% reduced metabolic rate (reduced CO[[2]] production) is seen in homozygous mutants compared to controls. There is no difference between females and males.

      Male homozygotes exhibit a reduction in waking activity compared to wild type, whereas no difference is seen in females.

      Females and males have a reduced median lifespan compared to controls (46% and 28% respectively).

      Mutants of both sexes are more sensitive to starvation (have an decreased starvation half life) than wild type flies.

      Males and females homozygous flies both sleep longer during the day than wild type flies. Female flies sleep for longer at nighttime whereas males do not differ from wild type.

      (De Luca et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      SdcBG02774
      (De Luca et al., 2010)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)