Allele Scer\GAL4^dome-PG14

General Information
Symbol	Scer\GAL4^dome-PG14	Species	S. cerevisiae
Name		FlyBase ID	FBal0130657
Feature type	allele	Associated gene	Scer\GAL4

Allele class
Mutagen	Delta2-3
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	Delta2-3 (Bourbon et al., 2002)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Insertion of a P{GawB} element 20bp upstream of the dome transcription start site. (Ghiglione et al., 2002)
Caused by insertion	P{GawB}dome^PG14 (Bourbon et al., 2002, Jung et al., 2005, Mandal et al., 2007, Ghiglione et al., 2002, Flaherty et al., 2009, Jacques et al., 2009, Sinenko et al., 2009, Sinenko et al., 2011, Sinenko et al., 2011, Luo and Sehgal, 2012, Rajan and Perrimon, 2012)
Cytology
Phenotypic Data
Phenotypic Class
	lethal \| heat sensitive, with Stat92E^HMS00035 (Rajan and Perrimon, 2012) locomotor rhythm defective, with dome^{ΔCYT.Scer\UAS} (Luo and Sehgal, 2012) small body \| adult stage, with Stat92E^HMS00035 (Rajan and Perrimon, 2012)
Phenotype Manifest In
	lymph gland derived hemocyte \| third instar larval stage, with arm^{S10.Scer\UAS.T:Hsap\MYC} (Sinenko et al., 2009) lymph gland derived hemocyte \| third instar larval stage, with arm^ΔN.Scer\UAS (Sinenko et al., 2009) lymph gland derived hemocyte \| third instar larval stage, with fz2^{ECD.GPI.Scer\UAS.T:Hsap\MYC} (Sinenko et al., 2009) lymph gland derived hemocyte \| third instar larval stage, with fz^Scer\UAS.N (Sinenko et al., 2009) lymph gland derived hemocyte \| third instar larval stage, with wg^{Scer\UAS.cHa.T:Ivir\HA1} (Sinenko et al., 2009)
Detailed Description
	Statement Reference
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	Scer\GAL4^dome-PG14
Name Synonym
Secondary FlyBase IDs

References ( 11 )
Research paper	Luo and Sehgal, 2012, Cell 148(4): 765--779 Regulation of Circadian Behavioral Output via a MicroRNA-JAK/STAT Circuit. [FBrf0217497] Rajan and Perrimon, 2012, Cell 151(1): 123--137 Drosophila cytokine unpaired 2 regulates physiological homeostasis by remotely controlling insulin secretion. [FBrf0219535] Sinenko et al., 2011, EMBO Rep. 13(1): 83--89 Oxidative stress in the haematopoietic niche regulates the cellular immune response in Drosophila. [FBrf0217071] Flaherty et al., 2009, Dev. Dyn. 238(9): 2235--2253 Genome-wide expression profiling in the Drosophila eye reveals unexpected repression of notch signaling by the JAK/STAT pathway. [FBrf0208590] Jacques et al., 2009, Int. J. Dev. Biol. 53(7): 1013--1022 A novel role of the glial fate determinant glial cells missing in hematopoiesis. [FBrf0208351] Sinenko et al., 2009, Dev. Cell 16(5): 756--763 Dual role of wingless signaling in stem-like hematopoietic precursor maintenance in Drosophila. [FBrf0207962] Mandal et al., 2007, Nature 446(7133): 320--324 A Hedgehog- and Antennapedia-dependent niche maintains Drosophila haematopoietic precursors. [FBrf0194088] Jung et al., 2005, Development 132(11): 2521--2533 The Drosophila lymph gland as a developmental model of hematopoiesis. [FBrf0187467] Bourbon et al., 2002, Mech. Dev. 110(1-2): 71--83 A P-insertion screen identifying novel X-linked essential genes in Drosophila. [FBrf0141645] Ghiglione et al., 2002, Development 129(23): 5437--5447 The Drosophila cytokine receptor Domeless controls border cell migration and epithelial polarization during oogenesis. [FBrf0151938]
Supplementary material	Sinenko et al., 2011, EMBO Rep. 13(1): Supplementary information. [FBrf0219127]

Allele Scer\GAL4dome-PG14

Allele Scer\GAL4^dome-PG14