Allele Dmel\Myd88^EP2535

General Information
Symbol	Dmel\Myd88^EP2535	Species	D. melanogaster
Name		FlyBase ID	FBal0130898
Feature type	allele	Associated gene	Dmel\Myd88

Map ( GBrowse )	Untitled Document
Allele class
Mutagen	P-element activity
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	P-element activity (Gene Disruption Project members, 2001-, Pena-Rangel et al., 2002, Charatsi et al., 2003)
Mutations Mapped to the Genome

Type Location Additional Notes References transposable element insertion site 2R:5,196,072..5,196,072 (Gene Disruption Project members, 2001-, Charatsi et al., 2003, Pena-Rangel et al., 2002, Tauszig-Delamasure et al., 2002)
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Insertion in the 5' untranslated region. (Tauszig-Delamasure et al., 2002)
Caused by insertion	P{EP}Myd88^EP2535 (Gene Disruption Project members, 2001-, Charatsi et al., 2003, Pena-Rangel et al., 2002, Tauszig-Delamasure et al., 2002)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In

Detailed Description
	Statement Reference
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement Reference Myd88^EP2535/Scer\GAL4^pnr-MD237 is an enhancer of visible phenotype of pnr^MD237 (Pena-Rangel et al., 2002)
Phenotype Manifest In
Enhancer of
Statement Reference Myd88^EP2535/Scer\GAL4^pnr-MD237 is an enhancer of chaeta phenotype of pnr^MD237 (Pena-Rangel et al., 2002)
Other
Statement Reference Myd88^EP2535, Scer\GAL4^pnr-MD237, pnr^MD237/pnr[+] has macrochaeta phenotype (Pena-Rangel et al., 2002) Myd88^EP2535, Scer\GAL4^pnr-MD237, pnr^MD237 has macrochaeta phenotype (Pena-Rangel et al., 2002)
Additional Comments
Genetic Interactions
Statement Reference pnr^MD237/+ adults expressing Myd88^EP2535 under the control of Scer\GAL4^pnr-MD237 have deformed macrochaetae. (Pena-Rangel et al., 2002)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer
	Selected as: a P{EP} insertion line that modifies the pnr^MD237/+ phenotype when expressed using Scer\GAL4^pnr-MD237. (Pena-Rangel et al., 2002)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	Myd88^EP2535
Name Synonym
Secondary FlyBase IDs

References ( 4 )
Research paper	Charatsi et al., 2003, Mech. Dev. 120(2): 219--226 Krapfen/dMyd88 is required for the establishment of dorsoventral pattern in the Drosophila embryo. [FBrf0155935] Pena-Rangel et al., 2002, Genetics 160(3): 1035--1050 A misexpression study examining dorsal thorax formation in Drosophila melanogaster. [FBrf0147055] Tauszig-Delamasure et al., 2002, Nat. Immunol. 3(1): 91--97 Drosophila MyD88 is required for the response to fungal and Gram-positive bacterial infections. [FBrf0141679]
Personal communication to FlyBase	Gene Disruption Project members, 2001-, (Computer file) (Computer file) [FBrf0132177]

Allele Dmel\Myd88EP2535

Allele Dmel\Myd88^EP2535