FB2025_01 , released February 20, 2025
Allele: Dmel\MoeGMA.UAS.GFP(S65T)
Open Close
General Information
Symbol
Dmel\MoeGMA.UAS.GFP(S65T)
Species
D. melanogaster
Name
FlyBase ID
FBal0130902
Feature type
allele
Associated gene
Dmel\Moe
Associated Insertion(s)
Carried in Construct
P{UAS-GMA}
Also Known As
UAS-GMA, UAS-GFP-gma, UAS-moesin-GFP, UAS-GFP-Moesin, UAS-GMA-GFP, UAS.gma-GFP, Moesin-GFP
Key Links
Transgenic product class
inframe_deletion
(Bloor and Kiehart, 2001)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Bloor and Kiehart, 2001)
Mutagen
in vitro construct
(Bloor and Kiehart, 2001)
Progenitor genotype
Carried in construct
P{UAS-GMA}
Cytology
Description

UASt sequences drive expression of the 137 amino acid actin binding domain of Moe tagged with GFP(S65T).

(Bloor and Kiehart, 2001)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Moe
Tagged with
GFP(S65T)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter or direct label
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      oogenesis & adult stage | female
      follicle cell
      (Dorman et al., 2004)
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Moe
      (Dorman et al., 2004)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Male germline stem cell clones expressing MoeGMA.Scer\UAS.T:Avic\GFP-S65T under the control of Scer\GAL4nos.PS show a considerably higher frequency of symmetric self renewal compared to controls.

      (Salzmann et al., 2013)

      Expression of MoeScer\UAS.T:Avic\GFP-S65T under the control of Scer\GAL4en-e16E has no effect on the distribution of actin in cells.

      (Dutta et al., 2002)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (4)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      MoeGMA.Scer\UAS.T:Avic\GFP-S65T
      MoeGMA.UAS.GFP(S65T)
      MoeScer\UAS.T:Avic\GFP-S65T
      (Pulido Companys et al., 2020)
      Name Synonyms
      Secondary FlyBase IDs
        References (55)