FlyBase Allele Report: Dmel\kibra[EP747]

General Information

Symbol

Dmel\kibra^EP747

Species

D. melanogaster

Name

FlyBase ID

FBal0131390

Feature type

allele

Associated gene

Dmel\kibra

Associated Insertion(s)

P{EP}kibra^EP747

Carried in Construct

Also Known As

CG7552^EP747

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Pena-Rangel et al., 2002, Tseng and Hariharan, 2002, Gene Disruption Project members, 2001-)

Progenitor genotype

Associated Insertion(s)

P{EP}kibra^EP747

Cytology

Description

Insertion in the 5' UTR.

(Genevet et al., 2010)

Allele components

Component

Use(s)

Inserted element

P{EP}

misexpression element

Regulatory region(s)

UAS

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3R:14,723,840..14,723,840 [-]

(Genevet et al., 2010, Genevet et al., 2010, Pena-Rangel et al., 2002, Tseng and Hariharan, 2002, Gene Disruption Project members, 2001-)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible, with Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

visible, with Scer\GAL4^GMR.PF

(Genevet et al., 2010)

Phenotype Manifest In

eye, with Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

eye, with Scer\GAL4^GMR.PF

(Genevet et al., 2010)

Detailed Description

Statement

Reference

Expression of CG33967^EP747 under the control of Scer\GAL4^ey.PH results in eyes that are somewhat reduced in size. Flies expressing CG33967^EP747 under the control of Scer\GAL4^hs.2sev have wild-type eyes. Flies expressing CG33967^EP747 under the control of Scer\GAL4^en-e16E have wild-type wings.

(Tseng and Hariharan, 2002)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Scer\GAL4^GMR.PF, kibra^EP747 has visible phenotype, suppressible | partially by hpo^5.1/hpo[+]

(Genevet et al., 2010)

NOT suppressed by

Statement

Reference

Scer\GAL4^ey.PH, kibra^EP747 has visible phenotype, non-suppressible by CycE^UAS.cLa, Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

Enhancer of

Statement

Reference

kibra^EP747/Scer\GAL4^pnr-MD237 is an enhancer of visible phenotype of pnr^MD237

(Pena-Rangel et al., 2002)

Suppressor of

Statement

Reference

kibra^EP747/Scer\GAL4^Tub.PU is a suppressor of visible | somatic clone phenotype of ex^e1

(Genevet et al., 2010)

NOT Suppressor of

Statement

Reference

kibra^EP747/Scer\GAL4^GMR.PF is a non-suppressor of visible phenotype of Scer\GAL4^GMR.PF, yki^UAS.cHa

(Genevet et al., 2010)

Other

Statement

Reference

Scer\GAL4^pnr-MD237, kibra^EP747, pnr^MD237/pnr[+] has lethal | pupal stage phenotype

(Pena-Rangel et al., 2002)

Scer\GAL4^pnr-MD237, kibra^EP747, pnr^MD237 has lethal | pupal stage phenotype

(Pena-Rangel et al., 2002)

Phenotype Manifest In

Suppressed by

Statement

Reference

Scer\GAL4^GMR.PF, kibra^EP747 has eye phenotype, suppressible | partially by hpo^5.1/hpo[+]

(Genevet et al., 2010)

NOT suppressed by

Statement

Reference

Scer\GAL4^ey.PH, kibra^EP747 has eye phenotype, non-suppressible by CycE^UAS.cLa, Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

Enhancer of

Statement

Reference

kibra^EP747/Scer\GAL4^pnr-MD237 is an enhancer of adult thorax phenotype of pnr^MD237

(Pena-Rangel et al., 2002)

Suppressor of

Statement

Reference

kibra^EP747/Scer\GAL4^Tub.PU is a suppressor of eye | somatic clone phenotype of ex^e1

(Genevet et al., 2010)

NOT Suppressor of

Statement

Reference

kibra^EP747/Scer\GAL4^GMR.PF is a non-suppressor of eye phenotype of Scer\GAL4^GMR.PF, yki^UAS.cHa

(Genevet et al., 2010)

Additional Comments

Genetic Interactions

Statement

Reference

Co-expression of CycE^Scer\UAS.cLa does not suppress the small eye phenotype caused by expression of CG33967^EP747 under the control of Scer\GAL4^ey.PH.

(Tseng and Hariharan, 2002)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Selected as: a P{EP} insertion line that modifies the pnr^MD237/+ phenotype when expressed using Scer\GAL4^pnr-MD237.

(Pena-Rangel et al., 2002)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

CG33967^EP747

CG7552^EP747

(Pena-Rangel et al., 2002, Tseng and Hariharan, 2002)

kibra^EP747

(Genevet et al., 2010)

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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