FlyBase Allele Report: Dmel\bol[EP3659]

General Information

Symbol

Dmel\bol^EP3659

Species

D. melanogaster

Name

FlyBase ID

FBal0131477

Feature type

allele

Associated gene

Dmel\bol

Associated Insertion(s)

P{EP}bol^EP3659

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Tseng and Hariharan, 2002, Gene Disruption Project members, 2001-)

Progenitor genotype

Associated Insertion(s)

P{EP}bol^EP3659

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{EP}

misexpression element

Regulatory region(s)

UAS

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3L:9,125,335..9,125,335 [-]

(Zhu et al., 2005, Tseng and Hariharan, 2002, Gene Disruption Project members, 2001-)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible, with Scer\GAL4^en-e16E

(Tseng and Hariharan, 2002)

visible, with Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

visible, with Scer\GAL4^hs.2sev

(Tseng and Hariharan, 2002)

Phenotype Manifest In

eye, with Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

eye, with Scer\GAL4^hs.2sev

(Tseng and Hariharan, 2002)

gamma Kenyon cell | pupal stage, with Scer\GAL4^ey-OK107

(Hoopfer et al., 2008)

gamma Kenyon cell | pupal stage, with Scer\GAL4^Tab2-201Y

(Hoopfer et al., 2008)

Kenyon cell | pupal stage, with Scer\GAL4^ey-OK107

(Hoopfer et al., 2008)

Kenyon cell | pupal stage, with Scer\GAL4^Tab2-201Y

(Hoopfer et al., 2008)

wing blade posterior compartment, with Scer\GAL4^en-e16E

(Tseng and Hariharan, 2002)

Detailed Description

Statement

Reference

Pruning of the axons of gamma kenyon cells during pupal stages is inhibited in bol^EP3659; Scer\GAL4^OK107 and bol^EP3659; Scer\GAL4^Tab2-201Y animals. The unpruned axons persist into adulthood.

(Hoopfer et al., 2008)

Expression of bol^EP3659 under the control of Scer\GAL4^ey.PH results in eyes that are slightly reduced in size. Flies expressing bol^EP3659 under the control of Scer\GAL4^hs.2sev have rough eyes. Flies expressing bol^EP3659 under the control of Scer\GAL4^en-e16E have wings with a smaller posterior compartment due to a reduced number of cells.

(Tseng and Hariharan, 2002)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

Scer\GAL4^GMR.PF/bol^EP3659 is an enhancer of visible phenotype of Scer\GAL4^GMR.PF, btl^λ.UAS, stumps^UAS.Tag:FLAG

(Zhu et al., 2005)

bol^EP3659, Scer\GAL4^GMR.PF is an enhancer of visible phenotype of Cdc42^L89.UAS, Scer\GAL4^GMR.PF