FlyBase Allele Report: Dmel\Usp15-31[KG04149]

General Information

Symbol

Dmel\Usp15-31^KG04149

Species

D. melanogaster

Name

FlyBase ID

FBal0131524

Feature type

allele

Associated gene

Dmel\Usp15-31

Associated Insertion(s)

P{SUPor-P}Usp15-31^KG04149

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

hypomorphic allele - molecular evidence

Mutagen

P-element activity

Nature of the Allele

Allele class

hypomorphic allele - molecular evidence

(Sinenko, 2017)

Mutagen

P-element activity

(Gene Disruption Project members, 2001-)

Progenitor genotype

Associated Insertion(s)

P{SUPor-P}Usp15-31^KG04149

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{SUPor-P}

insertional mutagenesis tool

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2R:24,744,084..24,744,084 [+]

(Sinenko, 2017, Gene Disruption Project members, 2001-)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

fertile

(Sinenko, 2017)

viable

(Sinenko, 2017)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Usp15-31^KG04149/Usp15-31[+] is a suppressor of visible | adult stage phenotype of Dronc^UAS.cSa, Scer\GAL4^GMR.PFa

(Sinenko, 2017)

Usp15-31^KG04149/Usp15-31[+] is a suppressor of abnormal eye color | adult stage phenotype of Dronc^UAS.cSa, Scer\GAL4^GMR.PFa

(Sinenko, 2017)

Usp15-31^KG04149/Usp15-31[+] is a suppressor | partially of abnormal eye color phenotype of Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PFa

(Sinenko, 2017)

Usp15-31^KG04149/Usp15-31[+] is a suppressor | partially of abnormal size | adult stage phenotype of Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PFa

(Sinenko, 2017)

Usp15-31^KG04149/Usp15-31[+] is a suppressor of visible | adult stage phenotype of grim^GMR.PC

(Sinenko, 2017)

Usp15-31^KG04149/Usp15-31[+] is a suppressor of abnormal eye color phenotype of grim^GMR.PC

(Sinenko, 2017)

Usp15-31^KG04149/Usp15-31[+] is a suppressor of abnormal size | adult stage phenotype of grim^GMR.PC

(Sinenko, 2017)

Usp15-31^KG04149/Usp15-31^KG04149 is a suppressor of visible | adult stage phenotype of grim^GMR.PC

(Sinenko, 2017)

Usp15-31^KG04149/Usp15-31^KG04149 is a suppressor of abnormal eye color phenotype of grim^GMR.PC

(Sinenko, 2017)

Usp15-31^KG04149/Usp15-31^KG04149 is a suppressor of abnormal size | adult stage phenotype of grim^GMR.PC

(Sinenko, 2017)

Usp15-31^KG04149/Usp15-31[+] is a suppressor | partially of visible | adult stage phenotype of Dronc^{S130A.UAS.cSa}, Scer\GAL4^GMR.PFa

(Sinenko, 2017)

Usp15-31^KG04149/Usp15-31[+] is a suppressor | partially of abnormal eye color phenotype of Dronc^{S130A.UAS.cSa}, Scer\GAL4^GMR.PFa

(Sinenko, 2017)

Usp15-31^KG04149/Usp15-31[+] is a suppressor | partially of visible | adult stage phenotype of Dcp-1^UAS.cKa, Scer\GAL4^GMR.PFa

(Sinenko, 2017)

Usp15-31^KG04149/Usp15-31[+] is a suppressor | partially of abnormal eye color phenotype of Dcp-1^UAS.cKa, Scer\GAL4^GMR.PFa

(Sinenko, 2017)

Usp15-31^KG04149/Usp15-31[+] is a suppressor | partially of visible | adult stage phenotype of Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PFa

(Sinenko, 2017)

Phenotype Manifest In

Suppressor of

Statement

Reference

Usp15-31^KG04149/Usp15-31[+] is a suppressor | partially of eye phenotype of Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PFa

(Sinenko, 2017)

Usp15-31^KG04149/Usp15-31[+] is a suppressor of eye phenotype of grim^GMR.PC

(Sinenko, 2017)

Usp15-31^KG04149/Usp15-31[+] is a suppressor of eye phenotype of Dronc^UAS.cSa, Scer\GAL4^GMR.PFa

(Sinenko, 2017)

Usp15-31^KG04149/Usp15-31^KG04149 is a suppressor of eye phenotype of grim^GMR.PC

(Sinenko, 2017)

Usp15-31^KG04149/Usp15-31[+] is a suppressor | partially of eye phenotype of Dronc^{S130A.UAS.cSa}, Scer\GAL4^GMR.PFa

(Sinenko, 2017)

Usp15-31^KG04149/Usp15-31[+] is a suppressor | partially of eye phenotype of Dcp-1^UAS.cKa, Scer\GAL4^GMR.PFa

(Sinenko, 2017)

Additional Comments

Genetic Interactions

Statement

Reference

The photoreceptor depigmentation phenotype characteristic for adult flies expressing Dronc^UAS.cSa or Dronc^{S130A.UAS.cSa} or Dcp-1^UAS.cKa under the control of Scer\GAL4^GMR.PFa is significantly suppressed by combination with a single copy of Usp15-31^KG04149. The eye phenotype (depigmentation and size reduction) induced by Scer\GAL4^GMR.PFa-driven expression of Diap1^{dsRNA.UAS.cLa} is slightly improved by combination with one copy of Usp15-31^KG04149 and either homo- or heterozygosity for Usp15-31^KG04149 also partially rescues the severe eye defects (almost complete depigmentation, rough surface, strong size reduction) characteristic for adult flies carrying two copies of grim^GMR.PC.

(Sinenko, 2017)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

13275

y¹ w^67c23; P{SUPor-P}Usp15-31^KG04149

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

CG30421^KG04149

(Sinenko, 2017)

CG9189^KG04149

DUSP31^KG04149

(Sinenko, 2017)

Usp15-31^KG04149

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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